| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.169847 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.15181 |
| FN1 | fibronectin 1 | 0.118314 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.105115 |
| TF | transferrin | 0.0912466 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0884914 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0814059 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0759083 |
| PCBP2 | poly(rC) binding protein 2 | 0.0728469 |
| DSPP | dentin sialophosphoprotein | 0.0704424 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0664728 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0664478 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0645538 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0639587 |
| VEGFA | vascular endothelial growth factor A | 0.0617731 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0588844 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0571316 |
| KIF1B | kinesin family member 1B | 0.0533843 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0519238 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0504653 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.049794 |
| RPL3 | ribosomal protein L3 | 0.049169 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.048664 |
| RPL11 | ribosomal protein L11 | 0.0480992 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0458782 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0457803 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0457204 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0455502 |
| AFDN | afadin, adherens junction formation factor | 0.044239 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0430199 |
| PEG10 | paternally expressed 10 | 0.0428535 |
| HELZ | helicase with zinc finger | 0.0427558 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0423213 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0421435 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0413355 |
| CPE | carboxypeptidase E | 0.0412021 |
| KIF5B | kinesin family member 5B | 0.0405642 |
| FMNL2 | formin-like 2 | 0.0399542 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0395244 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0394895 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0389295 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.038252 |
| ANO6 | anoctamin 6 | 0.0382458 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.036823 |
| CADM1 | cell adhesion molecule 1 | 0.0365065 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0356929 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0355312 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0354855 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.035197 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0349858 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0349615 |
| RBM39 | RNA binding motif protein 39 | 0.0348207 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.0347489 |
| TRIM26 | tripartite motif containing 26 | 0.0347266 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0344876 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0337133 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0335879 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0334532 |
| INSIG2 | insulin induced gene 2 | 0.0327872 |
| VMP1 | vacuole membrane protein 1 | 0.0324973 |
| HLF | hepatic leukemia factor | 0.0323965 |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.0319438 |
| LDHA | lactate dehydrogenase A | 0.0318374 |
| OLA1 | Obg-like ATPase 1 | 0.0317063 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0313886 |
| TNS1 | tensin 1 | 0.0312375 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0311015 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0307354 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0304987 |
| A2M | alpha-2-macroglobulin | 0.0304693 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0302074 |
| MATR3 | matrin 3 | 0.0299851 |
| AHSG | alpha-2-HS-glycoprotein | 0.0298417 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0294103 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0291476 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0286413 |
| YBX1 | Y box binding protein 1 | 0.0283339 |
| MYO1B | myosin IB | 0.0282611 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0281989 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0279089 |
| QKI | QKI, KH domain containing, RNA binding | 0.0277039 |
| NFIA | nuclear factor I/A | 0.0276011 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0275048 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0274084 |
| TGOLN2 | trans-golgi network protein 2 | 0.0274067 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0271545 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0270924 |
| PRELID2 | PRELI domain containing 2 | 0.0269527 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0266585 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0262116 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0261775 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0261206 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0260714 |
| NCKAP1 | NCK-associated protein 1 | 0.0259918 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0259772 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0258429 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.025592 |
| KIZ | kizuna centrosomal protein | 0.0253366 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0251769 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0251137 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.21164 |
| TMSB10 | thymosin beta 10 | -0.137843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.111972 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.105678 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.105131 |
| MT2A | metallothionein 2A | -0.0919285 |
| APOA2 | apolipoprotein A-II | -0.0848578 |
| FRMD5 | FERM domain containing 5 | -0.0847157 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0823753 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0785079 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0763941 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0721461 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0706149 |
| GPC6 | glypican 6 | -0.069773 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0610937 |
| EHBP1 | EH domain binding protein 1 | -0.0591893 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0586979 |
| VCL | vinculin | -0.0569678 |
| RPS19 | ribosomal protein S19 | -0.055633 |
| RIGI | RNA sensor RIG-I | -0.0536833 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0528498 |
| ASPH | aspartate beta-hydroxylase | -0.0504499 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0503337 |
| RPS24 | ribosomal protein S24 | -0.0493409 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.048683 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0482793 |
| FOXP1 | forkhead box P1 | -0.0477027 |
| ACTN4 | actinin, alpha 4 | -0.0458475 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0442912 |
| RPS8 | ribosomal protein S8 | -0.0435178 |
| PTCHD4 | patched domain containing 4 | -0.0430677 |
| MX2 | MX dynamin-like GTPase 2 | -0.0421278 |
| H1-0 | H1.0 linker histone | -0.0387188 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0383334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0378165 |
| ATXN1 | ataxin 1 | -0.0370238 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0364255 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0362106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0356133 |
| FERMT1 | fermitin family member 1 | -0.0354392 |
| RPL36 | ribosomal protein L36 | -0.035396 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0350496 |
| PGK1 | phosphoglycerate kinase 1 | -0.0345466 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.034539 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.033935 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0337755 |
| KRT8 | keratin 8, type II | -0.0325727 |
| SP100 | SP100 nuclear antigen | -0.0322563 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0320784 |
| PDLIM5 | PDZ and LIM domain 5 | -0.031889 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.03162 |
| ITGAV | integrin, alpha V | -0.0313117 |
| RPL31 | ribosomal protein L31 | -0.031298 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0311956 |
| RPS27A | ribosomal protein S27a | -0.0310071 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0307941 |
| S100A9 | S100 calcium binding protein A9 | -0.0306505 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0305003 |
| RAB7A | RAB7A, member RAS oncogene family | -0.030162 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0299284 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0299178 |
| RPL23 | ribosomal protein L23 | -0.0295341 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0294046 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0284477 |
| EGR1 | early growth response 1 | -0.0284009 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0282816 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0281635 |
| MAP1B | microtubule-associated protein 1B | -0.0279123 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0273952 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0272732 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0272343 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0271763 |
| RPL35A | ribosomal protein L35a | -0.0268172 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0265318 |
| RSU1 | Ras suppressor protein 1 | -0.0265165 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0262911 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0262767 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0261994 |
| PCNX4 | pecanex 4 | -0.0261595 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0258429 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0256758 |
| RPS21 | ribosomal protein S21 | -0.0256727 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0254989 |
| SMYD3 | SET and MYND domain containing 3 | -0.02544 |
| RPL9 | ribosomal protein L9 | -0.0253853 |
| FTL | ferritin, light polypeptide | -0.0252638 |
| CP | ceruloplasmin (ferroxidase) | -0.0252634 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0251761 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0250206 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.02487 |
| KRT19 | keratin 19, type I | -0.0248394 |
| MT1X | metallothionein 1X | -0.0242267 |
| UBXN4 | UBX domain protein 4 | -0.0241796 |
| RPL12 | ribosomal protein L12 | -0.0239242 |
| RPLP2 | ribosomal protein, large, P2 | -0.0237854 |
| GPC3 | glypican 3 | -0.0237682 |
| OSMR | oncostatin M receptor | -0.0234062 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.023084 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0230461 |
| CCDC91 | coiled-coil domain containing 91 | -0.0230434 |
