| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.160062 |
| NDRG1 | N-myc downstream regulated 1 | 0.111631 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.103194 |
| FAT1 | FAT atypical cadherin 1 | 0.0932341 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0885913 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0837763 |
| ITGA6 | integrin, alpha 6 | 0.0835366 |
| ANXA2 | annexin A2 | 0.0817842 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0808468 |
| TXNIP | thioredoxin interacting protein | 0.0800507 |
| FLNB | filamin B, beta | 0.0780565 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0768734 |
| DSPP | dentin sialophosphoprotein | 0.0739904 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0723523 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0693066 |
| TNS4 | tensin 4 | 0.0641659 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0619318 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0614219 |
| EZR | ezrin | 0.0604131 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.060409 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0535788 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0530092 |
| INSIG1 | insulin induced gene 1 | 0.0491067 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0480568 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0458293 |
| FNBP1L | formin binding protein 1-like | 0.0454953 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0448872 |
| KRT18 | keratin 18, type I | 0.044747 |
| PIGR | polymeric immunoglobulin receptor | 0.0441821 |
| RPL3 | ribosomal protein L3 | 0.0440577 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0439091 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0433428 |
| MLEC | malectin | 0.0422561 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.041583 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0413585 |
| MED13L | mediator complex subunit 13-like | 0.0404777 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0402894 |
| FDPS | farnesyl diphosphate synthase | 0.0402518 |
| VEGFA | vascular endothelial growth factor A | 0.0399782 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0397238 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.039582 |
| FAM13A | family with sequence similarity 13, member A | 0.0395287 |
| CALR | calreticulin | 0.0393994 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0390978 |
| TPM3 | tropomyosin 3 | 0.0388333 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0387419 |
| WDR45B | WD repeat domain 45B | 0.0386437 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.038629 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378965 |
| RNF145 | ring finger protein 145 | 0.0358021 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.035742 |
| PCBP2 | poly(rC) binding protein 2 | 0.0353027 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0346195 |
| CCNY | cyclin Y | 0.0345575 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0345545 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0345125 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0343612 |
| NUP58 | nucleoporin 58 | 0.0343194 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0342311 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0337975 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0324801 |
| FOSL1 | FOS-like antigen 1 | 0.0323745 |
| ABHD2 | abhydrolase domain containing 2 | 0.0321968 |
| ENO1 | enolase 1, (alpha) | 0.0318947 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0311983 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0311327 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.030847 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.030784 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0303572 |
| EPHA2 | EPH receptor A2 | 0.0303494 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0299814 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0296199 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.029216 |
| EPCAM | epithelial cell adhesion molecule | 0.0290377 |
| YTHDC1 | YTH domain containing 1 | 0.0284857 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0280488 |
| TMF1 | TATA element modulatory factor 1 | 0.0280387 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.027902 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0277268 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0273903 |
| TFG | TRK-fused gene | 0.0273117 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0268981 |
| ARLN | allregulin | 0.0264316 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0261794 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0261472 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0260934 |
| AFDN | afadin, adherens junction formation factor | 0.02603 |
| EMP1 | epithelial membrane protein 1 | 0.025955 |
| MCL1 | myeloid cell leukemia 1 | 0.0259356 |
| LAMB3 | laminin, beta 3 | 0.0258804 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0257728 |
| YBX1 | Y box binding protein 1 | 0.0254945 |
| KIF5B | kinesin family member 5B | 0.0254584 |
| RPL21 | ribosomal protein L21 | 0.0249652 |
| ITGB4 | integrin, beta 4 | 0.0249146 |
| CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | 0.0248768 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0247941 |
| DNM2 | dynamin 2 | 0.0247626 |
| RTN4 | reticulon 4 | 0.02476 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 0.0246378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.158636 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.153526 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.133413 |
| PTMA | prothymosin, alpha | -0.1168 |
| TMSB10 | thymosin beta 10 | -0.11388 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.103098 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0805991 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0805278 |
| RPS24 | ribosomal protein S24 | -0.0713459 |
| NPSR1 | neuropeptide S receptor 1 | -0.0641933 |
| MYO1E | myosin IE | -0.0628876 |
| RPLP1 | ribosomal protein, large, P1 | -0.0525245 |
| H1-0 | H1.0 linker histone | -0.0517819 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0450386 |
| KRT8 | keratin 8, type II | -0.0447844 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0440849 |
| RPLP2 | ribosomal protein, large, P2 | -0.0406722 |
| FHIT | fragile histidine triad | -0.0397992 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0387163 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0386671 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0383361 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0379271 |
| RPS6 | ribosomal protein S6 | -0.037305 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0370148 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0364568 |
| RPS21 | ribosomal protein S21 | -0.0348285 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0347798 |
| FOXP1 | forkhead box P1 | -0.0339789 |
| HMGB1 | high mobility group box 1 | -0.0327685 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0311139 |
| MT2A | metallothionein 2A | -0.0311091 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0308667 |
| RPS27A | ribosomal protein S27a | -0.0306966 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.029656 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0294502 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0291504 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0290111 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.028768 |
| ACTG1 | actin gamma 1 | -0.0287387 |
| DIAPH2 | diaphanous-related formin 2 | -0.027978 |
| RPS8 | ribosomal protein S8 | -0.0278772 |
| FUS | FUS RNA binding protein | -0.0278366 |
| GPHN | gephyrin | -0.0276924 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.027438 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0266571 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0260241 |
| TCF12 | transcription factor 12 | -0.0259763 |
| MYO1D | myosin ID | -0.0253632 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.025267 |
| RAD51B | RAD51 paralog B | -0.0250237 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0247663 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0246542 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0246433 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0243443 |
| RPL38 | ribosomal protein L38 | -0.0237665 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0236891 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.023575 |
| ABLIM1 | actin binding LIM protein 1 | -0.0235035 |
| SERINC5 | serine incorporator 5 | -0.0230723 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0229257 |
| IER3 | immediate early response 3 | -0.0228389 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0227713 |
| EXOC4 | exocyst complex component 4 | -0.0227518 |
| SMYD3 | SET and MYND domain containing 3 | -0.0227277 |
| RPL6 | ribosomal protein L6 | -0.0227114 |
| FRMD5 | FERM domain containing 5 | -0.0226405 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0221798 |
| RAB10 | RAB10, member RAS oncogene family | -0.0220635 |
| GDF15 | growth differentiation factor 15 | -0.0220606 |
| RPS23 | ribosomal protein S23 | -0.0219997 |
| RPL9 | ribosomal protein L9 | -0.0218774 |
| POF1B | premature ovarian failure, 1B | -0.02175 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0213546 |
| H3-3B | H3.3 histone B | -0.0212345 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0206608 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0204522 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0203159 |
| NEBL | nebulette | -0.020257 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0198317 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0197589 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0197352 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0196809 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0196621 |
| SBF2 | SET binding factor 2 | -0.019609 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0192936 |
| CCDC91 | coiled-coil domain containing 91 | -0.0192374 |
| EREG | epiregulin | -0.0191486 |
| MECOM | MDS1 and EVI1 complex locus | -0.0190655 |
| RPS19 | ribosomal protein S19 | -0.0190282 |
| FOXP2 | forkhead box P2 | -0.018959 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0189235 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0189014 |
| RPL35A | ribosomal protein L35a | -0.0186035 |
| RPS25 | ribosomal protein S25 | -0.0185674 |
| COMMD10 | COMM domain containing 10 | -0.0184202 |
| RPL8 | ribosomal protein L8 | -0.018173 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0181106 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0180345 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0179232 |
| RRBP1 | ribosome binding protein 1 | -0.0177965 |
