| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.141357 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.111627 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.109813 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.068001 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0665911 |
| PCDHB16 | protocadherin beta 16 | 0.0585597 |
| PKP2 | plakophilin 2 | 0.0574192 |
| RPS12 | ribosomal protein S12 | 0.0542509 |
| RPS2 | ribosomal protein S2 | 0.0536864 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0502502 |
| PRELID2 | PRELI domain containing 2 | 0.0484876 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0470787 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0438293 |
| RPLP0 | ribosomal protein, large, P0 | 0.0422943 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0408266 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0395772 |
| MLEC | malectin | 0.0393875 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0384363 |
| FOXO1 | forkhead box O1 | 0.0383742 |
| TXNRD1 | thioredoxin reductase 1 | 0.0380989 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0379306 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0367795 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0365253 |
| MKI67 | marker of proliferation Ki-67 | 0.0359606 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0358516 |
| CCPG1 | cell cycle progression 1 | 0.03384 |
| GDF15 | growth differentiation factor 15 | 0.0333547 |
| RPL12 | ribosomal protein L12 | 0.0332199 |
| TMF1 | TATA element modulatory factor 1 | 0.0318983 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0317014 |
| SHROOM3 | shroom family member 3 | 0.0313529 |
| ANXA2 | annexin A2 | 0.0311643 |
| RPL7 | ribosomal protein L7 | 0.0297059 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0296818 |
| RACK1 | receptor for activated C kinase 1 | 0.0291546 |
| RPL13A | ribosomal protein L13a | 0.0289472 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0288017 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0286509 |
| TRIM2 | tripartite motif containing 2 | 0.028216 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0281198 |
| PTEN | phosphatase and tensin homolog | 0.0280036 |
| PHF3 | PHD finger protein 3 | 0.0279569 |
| RPL21 | ribosomal protein L21 | 0.0278302 |
| MYOF | myoferlin | 0.0277009 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0275872 |
| FBXO32 | F-box protein 32 | 0.0275558 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0270628 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.0268645 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0267257 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0261398 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0257994 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0256843 |
| CDK19 | cyclin-dependent kinase 19 | 0.025464 |
| RPS7 | ribosomal protein S7 | 0.0252754 |
| HMGB2 | high mobility group box 2 | 0.0251218 |
| CENPF | centromere protein F, 350/400kDa | 0.0248452 |
| GOLGA4 | golgin A4 | 0.0247227 |
| EREG | epiregulin | 0.0245577 |
| KIF16B | kinesin family member 16B | 0.024252 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0241894 |
| INSIG1 | insulin induced gene 1 | 0.0237386 |
| CANX | calnexin | 0.0237194 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0236572 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0236538 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0233066 |
| RPS27L | ribosomal protein S27-like | 0.0233024 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232756 |
| SEC24D | SEC24 family member D | 0.0230476 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0228065 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0222751 |
| ATXN1 | ataxin 1 | 0.0222088 |
| ABHD17C | abhydrolase domain containing 17C | 0.0218834 |
| RNF43 | ring finger protein 43 | 0.0214469 |
| CLTC | clathrin, heavy chain (Hc) | 0.020717 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0206223 |
| TRIM31 | tripartite motif containing 31 | 0.0204533 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0204225 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0204204 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0200685 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0200604 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0199845 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0196367 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0196328 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0195324 |
| SLC38A1 | solute carrier family 38, member 1 | 0.019508 |
| TC2N | tandem C2 domains, nuclear | 0.0194455 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 0.0192611 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0192132 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0192013 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0191278 |
| MYO6 | myosin VI | 0.0190121 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0189448 |
| GPHN | gephyrin | 0.0187222 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0184783 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0183755 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.018218 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0180597 |
| HM13 | histocompatibility (minor) 13 | 0.0179274 |
| GOLM2 | golgi membrane protein 2 | 0.0176235 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0175105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.112383 |
| RPLP1 | ribosomal protein, large, P1 | -0.109814 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104362 |
| EZR | ezrin | -0.0973662 |
| TMSB10 | thymosin beta 10 | -0.0944123 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.088014 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0822009 |
| LDHA | lactate dehydrogenase A | -0.0816641 |
| RPS21 | ribosomal protein S21 | -0.0768584 |
| HLA-B | major histocompatibility complex, class I, B | -0.0747961 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0724131 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0722457 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0699458 |
| PTMA | prothymosin, alpha | -0.0685544 |
| RPS13 | ribosomal protein S13 | -0.0674807 |
| RPL35A | ribosomal protein L35a | -0.0642744 |
| FRMD5 | FERM domain containing 5 | -0.0639871 |
| KRT18 | keratin 18, type I | -0.0615961 |
| DIAPH1 | diaphanous-related formin 1 | -0.0591994 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0583625 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0575808 |
| RPLP2 | ribosomal protein, large, P2 | -0.0562203 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0556164 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0551848 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0539517 |
| DSPP | dentin sialophosphoprotein | -0.053932 |
| DSG3 | desmoglein 3 | -0.05172 |
| RPL38 | ribosomal protein L38 | -0.0515947 |
| MSI2 | musashi RNA-binding protein 2 | -0.0486879 |
| PERP | PERP, TP53 apoptosis effector | -0.0486048 |
| RBM25 | RNA binding motif protein 25 | -0.0485291 |
| SVIL | supervillin | -0.048149 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0480759 |
| RPS6 | ribosomal protein S6 | -0.0475948 |
| FBXO11 | F-box protein 11 | -0.0475457 |
| KRT8 | keratin 8, type II | -0.047273 |
| CUX1 | cut-like homeobox 1 | -0.0471525 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0465548 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0465052 |
| LMO7 | LIM domain 7 | -0.0454212 |
| POTEF | POTE ankyrin domain family, member F | -0.0453994 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0447003 |
| ANXA11 | annexin A11 | -0.0445553 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0441497 |
| RPL31 | ribosomal protein L31 | -0.0441449 |
| RPL36 | ribosomal protein L36 | -0.0437485 |
| RPL34 | ribosomal protein L34 | -0.0425135 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0421572 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0418498 |
| RPS23 | ribosomal protein S23 | -0.0405331 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0394819 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0394783 |
| RPL8 | ribosomal protein L8 | -0.0391675 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0390621 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0389223 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0387841 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.038359 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0383095 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0379879 |
| MCU | mitochondrial calcium uniporter | -0.0377896 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0376859 |
| TPM1 | tropomyosin 1 (alpha) | -0.037247 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0362809 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0362073 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0357144 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0355037 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0354996 |
| RPS14 | ribosomal protein S14 | -0.0353671 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0352802 |
| RPL36A | ribosomal protein L36a | -0.0347674 |
| S100A11 | S100 calcium binding protein A11 | -0.0345029 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0344647 |
| TPM4 | tropomyosin 4 | -0.0343006 |
| RNF213 | ring finger protein 213 | -0.0341656 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0341516 |
| SLMAP | sarcolemma associated protein | -0.0339168 |
| RPL28 | ribosomal protein L28 | -0.0338275 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0336498 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0334736 |
| ACTN4 | actinin, alpha 4 | -0.0333075 |
| RPL32 | ribosomal protein L32 | -0.0332179 |
| LAMA4 | laminin, alpha 4 | -0.0329417 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0329189 |
| TJP1 | tight junction protein 1 | -0.032889 |
| NPSR1 | neuropeptide S receptor 1 | -0.0327584 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0327332 |
| MYO5B | myosin VB | -0.0322705 |
| MX1 | MX dynamin-like GTPase 1 | -0.0320761 |
| RPS8 | ribosomal protein S8 | -0.0320373 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0318352 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0313312 |
| S100A6 | S100 calcium binding protein A6 | -0.0310194 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0307995 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0304132 |
| FOXO3 | forkhead box O3 | -0.0302207 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.029838 |
| FMNL2 | formin-like 2 | -0.0297033 |
| RPL37A | ribosomal protein L37a | -0.029575 |
| SP100 | SP100 nuclear antigen | -0.029513 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.029224 |
