| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120093 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.117268 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.09224 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0659774 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0652353 |
| PCBP2 | poly(rC) binding protein 2 | 0.0631835 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.05914 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0540015 |
| PTMA | prothymosin, alpha | 0.0512238 |
| ENO1 | enolase 1, (alpha) | 0.0511267 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0510571 |
| MYOF | myoferlin | 0.0470706 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0460113 |
| FNIP1 | folliculin interacting protein 1 | 0.0455587 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0450603 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.044965 |
| PKM | pyruvate kinase, muscle | 0.0442452 |
| YEATS2 | YEATS domain containing 2 | 0.0438404 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0428494 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0421666 |
| XPO1 | exportin 1 | 0.0420788 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0415193 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0412652 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0412544 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0404957 |
| FMNL2 | formin-like 2 | 0.0404376 |
| POTEF | POTE ankyrin domain family, member F | 0.040362 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0398345 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0387878 |
| ZNF292 | zinc finger protein 292 | 0.038179 |
| EXOC4 | exocyst complex component 4 | 0.0376556 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0363713 |
| DOCK11 | dedicator of cytokinesis 11 | 0.036167 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0356566 |
| CDK19 | cyclin-dependent kinase 19 | 0.0356405 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.03443 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0343428 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340821 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.03328 |
| ATXN2 | ataxin 2 | 0.0331481 |
| CADM2 | cell adhesion molecule 2 | 0.0330053 |
| CENPF | centromere protein F, 350/400kDa | 0.032778 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0326545 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0323927 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0321089 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0320611 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0319613 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0318855 |
| DPYD | dihydropyrimidine dehydrogenase | 0.031611 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0313254 |
| HELZ | helicase with zinc finger | 0.0311263 |
| EGFR | epidermal growth factor receptor | 0.0310222 |
| WASF2 | WAS protein family, member 2 | 0.0308571 |
| CD109 | CD109 molecule | 0.0307609 |
| PRELID2 | PRELI domain containing 2 | 0.0305439 |
| MSN | moesin | 0.0304337 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0303541 |
| EFNA5 | ephrin-A5 | 0.0302371 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0302306 |
| SET | SET nuclear proto-oncogene | 0.0301666 |
| GOLGA4 | golgin A4 | 0.0301236 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0298705 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0298361 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0296065 |
| MCL1 | myeloid cell leukemia 1 | 0.0293459 |
| ZNF148 | zinc finger protein 148 | 0.0292772 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0292423 |
| MAP4 | microtubule-associated protein 4 | 0.0291266 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.029074 |
| NDRG1 | N-myc downstream regulated 1 | 0.028891 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0287446 |
| RPL3 | ribosomal protein L3 | 0.0285442 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0283516 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0279414 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0277066 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0271173 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0265334 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0263454 |
| TPM3 | tropomyosin 3 | 0.0262154 |
| PLEC | plectin | 0.0261562 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0261491 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0259286 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0256701 |
| PLK2 | polo-like kinase 2 | 0.0256031 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0253595 |
| DENND1A | DENN/MADD domain containing 1A | 0.0251572 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0248295 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0246933 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0245651 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.024437 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0244203 |
| PTK2 | protein tyrosine kinase 2 | 0.0243908 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.02438 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0242165 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0240769 |
| MYO10 | myosin X | 0.0238998 |
| SETD5 | SET domain containing 5 | 0.0238654 |
| TNS3 | tensin 3 | 0.0238176 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.02365 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0235578 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.325043 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.148854 |
| MT2A | metallothionein 2A | -0.116561 |
| TXNRD1 | thioredoxin reductase 1 | -0.109714 |
| TP63 | tumor protein p63 | -0.100829 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0790098 |
| TMSB10 | thymosin beta 10 | -0.0784882 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0761368 |
| CD44 | CD44 molecule (Indian blood group) | -0.0712181 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0643374 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0617657 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.052747 |
| RIGI | RNA sensor RIG-I | -0.0523498 |
| MT1X | metallothionein 1X | -0.0497122 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0482091 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0478572 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0478345 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0469663 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0468579 |
| ACTG1 | actin gamma 1 | -0.0468189 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0412834 |
| KLF6 | Kruppel-like factor 6 | -0.0402234 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0400818 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0389233 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0379324 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0373747 |
| MT1E | metallothionein 1E | -0.0365758 |
| EGR1 | early growth response 1 | -0.036388 |
| AHNAK | AHNAK nucleoprotein | -0.0356363 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0352358 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0335289 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0332045 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0330597 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0329333 |
| PLSCR1 | phospholipid scramblase 1 | -0.032794 |
| RGS4 | regulator of G-protein signaling 4 | -0.0324549 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0323489 |
| SP100 | SP100 nuclear antigen | -0.0320326 |
| EMP1 | epithelial membrane protein 1 | -0.0315859 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.031364 |
| RUNX1 | runt-related transcription factor 1 | -0.0300102 |
| RPL12 | ribosomal protein L12 | -0.0299737 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0298644 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0296773 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0289258 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0285888 |
| HLA-B | major histocompatibility complex, class I, B | -0.0280192 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0276951 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0275586 |
| OSMR | oncostatin M receptor | -0.0273522 |
| TMEM41B | transmembrane protein 41B | -0.0263259 |
| YBX3 | Y box binding protein 3 | -0.0262518 |
| BMERB1 | bMERB domain containing 1 | -0.0259568 |
| EREG | epiregulin | -0.0258837 |
| ZNF217 | zinc finger protein 217 | -0.025799 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0253289 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0249615 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0243148 |
| HPCAL1 | hippocalcin-like 1 | -0.0242029 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0239994 |
| USP12 | ubiquitin specific peptidase 12 | -0.0235482 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0233491 |
| SGMS2 | sphingomyelin synthase 2 | -0.0233455 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0233137 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.022937 |
| PDE10A | phosphodiesterase 10A | -0.0228233 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0225035 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0224802 |
| FBXO11 | F-box protein 11 | -0.0221038 |
| JUN | jun proto-oncogene | -0.0220249 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0219619 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0211877 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0210852 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0206731 |
| FERMT1 | fermitin family member 1 | -0.0203801 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0202229 |
| ARF1 | ADP-ribosylation factor 1 | -0.0200591 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0194807 |
| SDC4 | syndecan 4 | -0.019457 |
| RPL4 | ribosomal protein L4 | -0.0193066 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0192987 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0192004 |
| MB21D2 | Mab-21 domain containing 2 | -0.0191304 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0188724 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0188654 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0186993 |
| RPL38 | ribosomal protein L38 | -0.0186082 |
| RPLP1 | ribosomal protein, large, P1 | -0.0185717 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.018534 |
| VMP1 | vacuole membrane protein 1 | -0.0182963 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0182404 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0180818 |
| SRGN | serglycin | -0.0180445 |
| ZNF267 | zinc finger protein 267 | -0.017978 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0177868 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0177195 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0170468 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.017017 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0170153 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0169771 |
