| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.340714 |
| PLEC | plectin | 0.119941 |
| LOC112694756 | uncharaterized LOC112694756 | 0.110881 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.101407 |
| ARRDC3 | arrestin domain containing 3 | 0.0838995 |
| FAM13A | family with sequence similarity 13, member A | 0.0793088 |
| NDRG1 | N-myc downstream regulated 1 | 0.0792214 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0714362 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0702062 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0680078 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0672066 |
| HDLBP | high density lipoprotein binding protein | 0.0615674 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0607154 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0606203 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0584507 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0579442 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0537882 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0501801 |
| LAMB3 | laminin, beta 3 | 0.0499548 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0492456 |
| EGFR | epidermal growth factor receptor | 0.0454037 |
| ANXA2 | annexin A2 | 0.0451963 |
| MYOF | myoferlin | 0.0444019 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0438403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0433288 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0427457 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0410707 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.040589 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0401084 |
| CTBP2 | C-terminal binding protein 2 | 0.0393054 |
| WDR45B | WD repeat domain 45B | 0.0377936 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0371815 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0366334 |
| GRAMD1B | GRAM domain containing 1B | 0.0362944 |
| FNBP1L | formin binding protein 1-like | 0.0361339 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0354013 |
| H1-0 | H1.0 linker histone | 0.0344681 |
| HELZ | helicase with zinc finger | 0.0342732 |
| IGF1R | insulin-like growth factor 1 receptor | 0.033842 |
| TES | testin LIM domain protein | 0.0333505 |
| SCEL | sciellin | 0.0317425 |
| MORF4L2 | mortality factor 4 like 2 | 0.0315021 |
| USP3 | ubiquitin specific peptidase 3 | 0.031455 |
| HBP1 | HMG-box transcription factor 1 | 0.0314274 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0313695 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0312619 |
| TMEM165 | transmembrane protein 165 | 0.031183 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0310216 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.030739 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0306025 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0300516 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0300078 |
| ACTG1 | actin gamma 1 | 0.029729 |
| TPD52 | tumor protein D52 | 0.0297024 |
| XPO1 | exportin 1 | 0.0294486 |
| CD163L1 | CD163 molecule-like 1 | 0.0292834 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0291068 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0290071 |
| LMO7 | LIM domain 7 | 0.0289812 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.028401 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0273489 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.027182 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0269834 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0269644 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0269515 |
| PYGL | phosphorylase, glycogen, liver | 0.0268071 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0266641 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0265575 |
| CCNY | cyclin Y | 0.0263259 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0260799 |
| NCKAP1 | NCK-associated protein 1 | 0.0260793 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0257811 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0257523 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.02567 |
| YTHDC1 | YTH domain containing 1 | 0.0252141 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.025058 |
| OGA | O-GlcNAcase | 0.0248993 |
| STAG2 | stromal antigen 2 | 0.0248155 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0247319 |
| ANXA5 | annexin A5 | 0.0246961 |
| PDE8A | phosphodiesterase 8A | 0.024419 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0243532 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242229 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.023683 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233426 |
| ECT2 | epithelial cell transforming 2 | 0.02314 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0230197 |
| ATP13A3 | ATPase type 13A3 | 0.0227991 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.022753 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0227174 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0227162 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.022713 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0227049 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0223992 |
| UVRAG | UV radiation resistance associated | 0.0223838 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0222434 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0221473 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0220952 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0220473 |
| TLK1 | tousled-like kinase 1 | 0.0219746 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.201069 |
| RPS3 | ribosomal protein S3 | -0.0985152 |
| LAMC2 | laminin, gamma 2 | -0.0821536 |
| TMSB10 | thymosin beta 10 | -0.0815087 |
| UBC | ubiquitin C | -0.0722081 |
| RPS27A | ribosomal protein S27a | -0.0717453 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0686741 |
| RPL37A | ribosomal protein L37a | -0.0615101 |
| RPS12 | ribosomal protein S12 | -0.0582701 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0553256 |
| MT2A | metallothionein 2A | -0.0507236 |
| RPS6 | ribosomal protein S6 | -0.0483871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0476173 |
| CCNL1 | cyclin L1 | -0.0459732 |
| RPS8 | ribosomal protein S8 | -0.0447764 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0424353 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0410827 |
| EGR1 | early growth response 1 | -0.0408843 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0383236 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0368801 |
| RPS24 | ribosomal protein S24 | -0.0355947 |
| RPS17 | ribosomal protein S17 | -0.035581 |
| RPL31 | ribosomal protein L31 | -0.0352552 |
| RPS27 | ribosomal protein S27 | -0.0351652 |
| SEC61G | Sec61 gamma subunit | -0.0350663 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0343252 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0332252 |
| HLA-B | major histocompatibility complex, class I, B | -0.0330863 |
| RPL5 | ribosomal protein L5 | -0.032006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0313428 |
| FTL | ferritin, light polypeptide | -0.0299945 |
| RPS29 | ribosomal protein S29 | -0.0297604 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0296846 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0287709 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0282715 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0279941 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0276598 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.027595 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0271711 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0271563 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0270546 |
| FRY | furry homolog (Drosophila) | -0.0268635 |
| KIAA1217 | KIAA1217 | -0.0261334 |
| RPLP2 | ribosomal protein, large, P2 | -0.0260912 |
| OSMR | oncostatin M receptor | -0.0260726 |
| RPS14 | ribosomal protein S14 | -0.0259994 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0256628 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0254073 |
| PAPOLA | poly(A) polymerase alpha | -0.025401 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0253247 |
| WDR26 | WD repeat domain 26 | -0.0252835 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.024931 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0248166 |
| RPL26 | ribosomal protein L26 | -0.0246584 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0243092 |
| RPL37 | ribosomal protein L37 | -0.0242192 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0236767 |
| RPS23 | ribosomal protein S23 | -0.0234875 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0229502 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0228797 |
| RPS2 | ribosomal protein S2 | -0.0228747 |
| TOP1 | topoisomerase (DNA) I | -0.0228236 |
| RPS19 | ribosomal protein S19 | -0.0228084 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0227114 |
| CST3 | cystatin C | -0.0226015 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0225981 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0225553 |
| IFI44L | interferon-induced protein 44-like | -0.0224164 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0223965 |
| RPL19 | ribosomal protein L19 | -0.0222648 |
| PNN | pinin, desmosome associated protein | -0.0222548 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0221626 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.021917 |
| RPL9 | ribosomal protein L9 | -0.021901 |
| PMP22 | peripheral myelin protein 22 | -0.0218623 |
| HM13 | histocompatibility (minor) 13 | -0.0213223 |
| AREG | amphiregulin | -0.0212738 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0212407 |
| CCDC91 | coiled-coil domain containing 91 | -0.0210562 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0209692 |
| S100P | S100 calcium binding protein P | -0.0207944 |
| RPL36A | ribosomal protein L36a | -0.0202086 |
| HDAC9 | histone deacetylase 9 | -0.0202028 |
| B2M | beta-2-microglobulin | -0.0201607 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0200744 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0200706 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.020061 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0198966 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.019791 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0195544 |
| RPS25 | ribosomal protein S25 | -0.0194306 |
| TMEM87A | transmembrane protein 87A | -0.0193874 |
| S100A11 | S100 calcium binding protein A11 | -0.0189625 |
| ASPH | aspartate beta-hydroxylase | -0.018853 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0187861 |
| SLTM | SAFB-like, transcription modulator | -0.0185378 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0183621 |
| PLAUR | plasminogen activator, urokinase receptor | -0.018336 |
| SYAP1 | synapse associated protein 1 | -0.0181272 |
| RPL12 | ribosomal protein L12 | -0.0180352 |
