| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | 0.143674 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.107678 |
| CMIP | c-Maf inducing protein | 0.10761 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0896539 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0770602 |
| SVIL | supervillin | 0.0680863 |
| ACTG1 | actin gamma 1 | 0.0663682 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0633665 |
| GRAMD1B | GRAM domain containing 1B | 0.0568097 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0562719 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0535135 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0531913 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0530296 |
| EGFR | epidermal growth factor receptor | 0.0528116 |
| TXNRD1 | thioredoxin reductase 1 | 0.0513081 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0495312 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0494146 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0492587 |
| HDAC9 | histone deacetylase 9 | 0.0490425 |
| VIM | vimentin | 0.0488519 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0488121 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0481492 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0477076 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0474568 |
| PYGL | phosphorylase, glycogen, liver | 0.046984 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0467536 |
| LDHA | lactate dehydrogenase A | 0.0467251 |
| FMNL2 | formin-like 2 | 0.0439905 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0435935 |
| ACTN1 | actinin, alpha 1 | 0.0427245 |
| AHNAK | AHNAK nucleoprotein | 0.0411976 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0403915 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0399708 |
| S100A6 | S100 calcium binding protein A6 | 0.039725 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0396274 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0392627 |
| PLEC | plectin | 0.0390821 |
| RPL3 | ribosomal protein L3 | 0.0388245 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0387256 |
| APP | amyloid beta (A4) precursor protein | 0.0381209 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0368476 |
| RASAL2 | RAS protein activator like 2 | 0.036836 |
| MYOF | myoferlin | 0.0367924 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.036168 |
| TPM4 | tropomyosin 4 | 0.0360039 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0354443 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0354017 |
| USP34 | ubiquitin specific peptidase 34 | 0.0350776 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0349541 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0348556 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0344558 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0344168 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0343006 |
| CUX1 | cut-like homeobox 1 | 0.0335873 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0335245 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0331045 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0325161 |
| FLNB | filamin B, beta | 0.0324957 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0321754 |
| OSMR | oncostatin M receptor | 0.0314567 |
| PTK2 | protein tyrosine kinase 2 | 0.0307149 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0305793 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.030114 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0296932 |
| UTRN | utrophin | 0.0295979 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0293447 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0288968 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0287688 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0287135 |
| WDR43 | WD repeat domain 43 | 0.0286097 |
| CYTH1 | cytohesin 1 | 0.028056 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0279106 |
| VCL | vinculin | 0.027711 |
| DST | dystonin | 0.0274932 |
| PDE8A | phosphodiesterase 8A | 0.0273899 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.027034 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0269175 |
| HLA-C | major histocompatibility complex, class I, C | 0.0269112 |
| SMAD3 | SMAD family member 3 | 0.0263521 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0260025 |
| NTN4 | netrin 4 | 0.0257472 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0256507 |
| SNX14 | sorting nexin 14 | 0.0255324 |
| FLNA | filamin A, alpha | 0.0253961 |
| CAVIN1 | caveolae associated protein 1 | 0.0252875 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0250836 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025037 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0249864 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0245367 |
| KYNU | kynureninase | 0.0244478 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0244278 |
| HDGF | hepatoma-derived growth factor | 0.0243924 |
| CFDP1 | craniofacial development protein 1 | 0.0241185 |
| ERBIN | erbb2 interacting protein | 0.0238234 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0237877 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0237436 |
| GLIS3 | GLIS family zinc finger 3 | 0.0236039 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.0235281 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0234999 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0232351 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.227045 |
| FTL | ferritin, light polypeptide | -0.171141 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131378 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.12446 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.106464 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0873286 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0720104 |
| TMSB10 | thymosin beta 10 | -0.0717806 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0712394 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0690114 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.058829 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0542594 |
| RPL19 | ribosomal protein L19 | -0.0533873 |
| RPLP0 | ribosomal protein, large, P0 | -0.044568 |
| CCNL1 | cyclin L1 | -0.042269 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0392411 |
| HMGB1 | high mobility group box 1 | -0.036016 |
| PTMA | prothymosin, alpha | -0.0352027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0349553 |
| YBX1 | Y box binding protein 1 | -0.0331066 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0329255 |
| USP3 | ubiquitin specific peptidase 3 | -0.0320436 |
| HMGA1 | high mobility group AT-hook 1 | -0.0314902 |
| PFN1 | profilin 1 | -0.0314059 |
| MT1X | metallothionein 1X | -0.031239 |
| RPS19 | ribosomal protein S19 | -0.0307289 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0298353 |
| RPS6 | ribosomal protein S6 | -0.0292301 |
| RPL23 | ribosomal protein L23 | -0.0284051 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273957 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0266966 |
| FGG | fibrinogen gamma chain | -0.0257805 |
| RBM39 | RNA binding motif protein 39 | -0.0254879 |
| CLU | clusterin | -0.0242218 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0241744 |
| TMEM87A | transmembrane protein 87A | -0.0236313 |
| FUS | FUS RNA binding protein | -0.0234912 |
| LDHB | lactate dehydrogenase B | -0.0231116 |
| RPS23 | ribosomal protein S23 | -0.0228499 |
| ANXA1 | annexin A1 | -0.0227716 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0225836 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0222126 |
| IFRD1 | interferon-related developmental regulator 1 | -0.022011 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0208276 |
| RPS5 | ribosomal protein S5 | -0.0200228 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0199821 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.019916 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0198999 |
| RPL23A | ribosomal protein L23a | -0.0196847 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0196137 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0195781 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0192653 |
| WWOX | WW domain containing oxidoreductase | -0.0191236 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0186189 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0185812 |
| RPS8 | ribosomal protein S8 | -0.0182904 |
| SERF2 | small EDRK-rich factor 2 | -0.0180985 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0180429 |
| MORF4L1 | mortality factor 4 like 1 | -0.0179505 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0178873 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0178448 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0172671 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0172183 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0170549 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0168648 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0168568 |
| TCIM | transcriptional and immune response regulator | -0.0164845 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0164522 |
| RPL32 | ribosomal protein L32 | -0.0164311 |
| RPS21 | ribosomal protein S21 | -0.0163723 |
| RPL28 | ribosomal protein L28 | -0.0163295 |
| ECT2 | epithelial cell transforming 2 | -0.0161216 |
| S100A11 | S100 calcium binding protein A11 | -0.0160297 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0159477 |
| ZNF292 | zinc finger protein 292 | -0.0157857 |
| RBM25 | RNA binding motif protein 25 | -0.0156214 |
| RPL36 | ribosomal protein L36 | -0.0155335 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0152066 |
| RPL8 | ribosomal protein L8 | -0.0151445 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.015035 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | -0.0149562 |
| CCNK | cyclin K | -0.0148795 |
| RPS29 | ribosomal protein S29 | -0.0147678 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0147186 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0146674 |
| S100A10 | S100 calcium binding protein A10 | -0.0145602 |
| TNPO1 | transportin 1 | -0.0145013 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0141719 |
| TUBA1B | tubulin, alpha 1b | -0.0139947 |
| RPS20 | ribosomal protein S20 | -0.0137501 |
| GOLM2 | golgi membrane protein 2 | -0.0137344 |
| FOXJ3 | forkhead box J3 | -0.0136036 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0135449 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0134291 |
| POU2F1 | POU class 2 homeobox 1 | -0.0134205 |
| FGA | fibrinogen alpha chain | -0.013418 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0133787 |
| CPNE8 | copine VIII | -0.0133707 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0133098 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.0131956 |
