| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.100433 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0890996 |
| GOLGA4 | golgin A4 | 0.0859011 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.084888 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0810786 |
| ZNF292 | zinc finger protein 292 | 0.0807108 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.080118 |
| DST | dystonin | 0.0781258 |
| NF1 | neurofibromin 1 | 0.0751707 |
| ANXA2 | annexin A2 | 0.0734482 |
| ENO1 | enolase 1, (alpha) | 0.0677017 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0668899 |
| RPL12 | ribosomal protein L12 | 0.0667808 |
| SETX | senataxin | 0.0663916 |
| RPS16 | ribosomal protein S16 | 0.0647643 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0638715 |
| APP | amyloid beta (A4) precursor protein | 0.0638046 |
| DENND1A | DENN/MADD domain containing 1A | 0.0635885 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0629627 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0629208 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0620841 |
| SERINC5 | serine incorporator 5 | 0.0608061 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0607538 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0596696 |
| MT2A | metallothionein 2A | 0.0572951 |
| RAD51B | RAD51 paralog B | 0.0571229 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0569752 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0566401 |
| XPO1 | exportin 1 | 0.0562194 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0549984 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0533755 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0529363 |
| NUP153 | nucleoporin 153kDa | 0.0528227 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0528052 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0519809 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0505 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0503841 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0498984 |
| TMEM165 | transmembrane protein 165 | 0.0491974 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0490363 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0489396 |
| GPATCH2L | G patch domain containing 2-like | 0.0477059 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0470936 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0469727 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0468738 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0467055 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0465125 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0464365 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0464069 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0457569 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.045389 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0448359 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0447618 |
| RTN4 | reticulon 4 | 0.0446981 |
| KIAA1217 | KIAA1217 | 0.0446358 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0444896 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0439521 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0437243 |
| LAMA4 | laminin, alpha 4 | 0.0436793 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0435405 |
| VCL | vinculin | 0.0434512 |
| CCNY | cyclin Y | 0.0433324 |
| MAP1B | microtubule-associated protein 1B | 0.0427582 |
| KIF5B | kinesin family member 5B | 0.0424688 |
| NBAS | neuroblastoma amplified sequence | 0.0422586 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0421583 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0421105 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.041464 |
| GNAS | GNAS complex locus | 0.0413536 |
| SETD5 | SET domain containing 5 | 0.0413048 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0409073 |
| NONO | non-POU domain containing, octamer-binding | 0.0407089 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0406325 |
| ANO6 | anoctamin 6 | 0.0405328 |
| SBF2 | SET binding factor 2 | 0.0405163 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0400653 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0400306 |
| RPL23 | ribosomal protein L23 | 0.0398702 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0398536 |
| COG5 | component of oligomeric golgi complex 5 | 0.0395187 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0395052 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0389459 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0386838 |
| B2M | beta-2-microglobulin | 0.038459 |
| NLGN1 | neuroligin 1 | 0.0384342 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0380107 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0377265 |
| STC1 | stanniocalcin 1 | 0.037329 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0370723 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364703 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0362931 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.036205 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0361898 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0361793 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0360228 |
| MYOF | myoferlin | 0.0357082 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0345483 |
| CUL3 | cullin 3 | 0.0344003 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0342793 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0338724 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.14572 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.143816 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.124534 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.119542 |
| LAMB3 | laminin, beta 3 | -0.106428 |
| PLAUR | plasminogen activator, urokinase receptor | -0.10234 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0964484 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0948113 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0885429 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0848824 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0848026 |
| MYO1E | myosin IE | -0.0763255 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0749371 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0736279 |
| AHNAK | AHNAK nucleoprotein | -0.0722978 |
| KRT17 | keratin 17, type I | -0.0703663 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0701751 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0666424 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0641386 |
| VIM | vimentin | -0.061592 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0611469 |
| ATOSA | atos homolog A | -0.0606395 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0586447 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0581926 |
| PKM | pyruvate kinase, muscle | -0.0580403 |
| MMP1 | matrix metallopeptidase 1 | -0.0576224 |
| S100A9 | S100 calcium binding protein A9 | -0.0574862 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0570988 |
| ACTG1 | actin gamma 1 | -0.0560274 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0557811 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0539281 |
| FRMD5 | FERM domain containing 5 | -0.0522511 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0519324 |
| KYNU | kynureninase | -0.0516621 |
| RUNX1 | runt-related transcription factor 1 | -0.0516495 |
| RBM47 | RNA binding motif protein 47 | -0.0512633 |
| S100A10 | S100 calcium binding protein A10 | -0.0510148 |
| MXD1 | MAX dimerization protein 1 | -0.0506074 |
| WASF2 | WAS protein family, member 2 | -0.0505775 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.0500649 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0499978 |
| MYO10 | myosin X | -0.0491703 |
| SNX9 | sorting nexin 9 | -0.0490474 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0489233 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0489009 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0488966 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0484966 |
| MUC16 | mucin 16, cell surface associated | -0.0471893 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0470009 |
| CD44 | CD44 molecule (Indian blood group) | -0.0469021 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.046602 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0461367 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0461206 |
| RPS11 | ribosomal protein S11 | -0.0460731 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0456322 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0455175 |
| TJP1 | tight junction protein 1 | -0.0452975 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0448464 |
| NPTN | neuroplastin | -0.043916 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0436771 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.043475 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.043139 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0427328 |
| ABHD17C | abhydrolase domain containing 17C | -0.0426261 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0424907 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0422704 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0420264 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0420024 |
| CORO1C | coronin, actin binding protein, 1C | -0.0416513 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0416409 |
| DSPP | dentin sialophosphoprotein | -0.041465 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0412091 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0410357 |
| IER3 | immediate early response 3 | -0.0408976 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.040437 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.039828 |
| ERBIN | erbb2 interacting protein | -0.0398103 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0396299 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0393922 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0391358 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0390457 |
| TMSB10 | thymosin beta 10 | -0.0388393 |
| POTEF | POTE ankyrin domain family, member F | -0.0386633 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0386213 |
| TPR | translocated promoter region, nuclear basket protein | -0.0384246 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0382577 |
| LAMC2 | laminin, gamma 2 | -0.0381336 |
| STEAP4 | STEAP family member 4 | -0.0379549 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0372803 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0369023 |
| IGF2 | insulin-like growth factor 2 | -0.0368917 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0368072 |
| HOMER1 | homer scaffolding protein 1 | -0.0366588 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0360377 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0357696 |
| NBEAL1 | neurobeachin-like 1 | -0.0357431 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0347637 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.034703 |
| INTS6 | integrator complex subunit 6 | -0.0345778 |
| ARF4 | ADP-ribosylation factor 4 | -0.0344662 |
