| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine (dihydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.214102 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.129716 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.127662 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.124489 |
| ENO1 | enolase 1, (alpha) | 0.123076 |
| RAB1A | RAB1A, member RAS oncogene family | 0.121523 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.109981 |
| DOCK5 | dedicator of cytokinesis 5 | 0.100061 |
| JMJD1C | jumonji domain containing 1C | 0.0982789 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0978906 |
| ATP13A3 | ATPase type 13A3 | 0.0977489 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.091098 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0870311 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0867241 |
| RPL11 | ribosomal protein L11 | 0.0865473 |
| PGK1 | phosphoglycerate kinase 1 | 0.0856263 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0840445 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0798893 |
| ASPH | aspartate beta-hydroxylase | 0.0767601 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0744572 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0743339 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0738147 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0724526 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0707232 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0703734 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0691983 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0687463 |
| RPLP0 | ribosomal protein, large, P0 | 0.067515 |
| OGA | O-GlcNAcase | 0.066967 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0668814 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.062847 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0624911 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0614344 |
| COL6A3 | collagen, type VI, alpha 3 | 0.060217 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0600266 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0596444 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0590717 |
| NBAS | neuroblastoma amplified sequence | 0.0588628 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0587063 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0585461 |
| ITGA6 | integrin, alpha 6 | 0.0583519 |
| GPC6 | glypican 6 | 0.0575907 |
| MAP1B | microtubule-associated protein 1B | 0.0574488 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0567529 |
| USP3 | ubiquitin specific peptidase 3 | 0.0566511 |
| RAD51B | RAD51 paralog B | 0.0549309 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0549122 |
| LSAMP | limbic system-associated membrane protein | 0.0546918 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0544811 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0544059 |
| RORA | RAR-related orphan receptor A | 0.0540864 |
| VIM | vimentin | 0.0538192 |
| RPL35A | ribosomal protein L35a | 0.0537198 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0531171 |
| MED13L | mediator complex subunit 13-like | 0.0520506 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0519034 |
| SPAG9 | sperm associated antigen 9 | 0.0514815 |
| ATXN1 | ataxin 1 | 0.051254 |
| PDE10A | phosphodiesterase 10A | 0.0511815 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0511288 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0511159 |
| NF1 | neurofibromin 1 | 0.0504564 |
| RACK1 | receptor for activated C kinase 1 | 0.04962 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0484735 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0477317 |
| ZNF148 | zinc finger protein 148 | 0.0464505 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0456234 |
| MSI2 | musashi RNA-binding protein 2 | 0.0451869 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0443024 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0438158 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0437141 |
| RPS16 | ribosomal protein S16 | 0.0428968 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0420326 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0385936 |
| WDR45B | WD repeat domain 45B | 0.0383439 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0383364 |
| PCBP2 | poly(rC) binding protein 2 | 0.0380363 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0379577 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0379167 |
| RPS24 | ribosomal protein S24 | 0.0378446 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0371091 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.036202 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0353816 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0350931 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0348775 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0347723 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.03434 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0343051 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0340896 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0338269 |
| ZNF292 | zinc finger protein 292 | 0.0338153 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0332999 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0323064 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0322055 |
| MED13 | mediator complex subunit 13 | 0.0316432 |
| FMNL2 | formin-like 2 | 0.0314694 |
| RTN4 | reticulon 4 | 0.0314494 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0307911 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0300815 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0300603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.188702 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.121636 |
| MT2A | metallothionein 2A | -0.116839 |
| EXT1 | exostosin glycosyltransferase 1 | -0.115927 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0943306 |
| LAMB3 | laminin, beta 3 | -0.0931204 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0923827 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0911292 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0884449 |
| FN1 | fibronectin 1 | -0.0877659 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0842139 |
| COL5A1 | collagen, type V, alpha 1 | -0.0722487 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0718616 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0716463 |
| EFNA5 | ephrin-A5 | -0.0711983 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0703942 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0701804 |
| TPM4 | tropomyosin 4 | -0.0701407 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0693115 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0679783 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0667581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0666423 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0626733 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0624683 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0616764 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0616366 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0611209 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0605513 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.060548 |
| RPS13 | ribosomal protein S13 | -0.0600713 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0589458 |
| MSN | moesin | -0.0577591 |
| TXNRD1 | thioredoxin reductase 1 | -0.0566492 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0564382 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0543772 |
| USP34 | ubiquitin specific peptidase 34 | -0.0539031 |
| TPM3 | tropomyosin 3 | -0.0537455 |
| SLTM | SAFB-like, transcription modulator | -0.0525516 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0519374 |
| RPLP1 | ribosomal protein, large, P1 | -0.0510283 |
| LDHA | lactate dehydrogenase A | -0.0502734 |
| TMSB10 | thymosin beta 10 | -0.0501925 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.049006 |
| RPS25 | ribosomal protein S25 | -0.0488347 |
| YBX3 | Y box binding protein 3 | -0.0484824 |
| RPL4 | ribosomal protein L4 | -0.0477776 |
| POTEF | POTE ankyrin domain family, member F | -0.0476215 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0474149 |
| FLNB | filamin B, beta | -0.0474148 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.047323 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0473223 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0470115 |
| MAP4 | microtubule-associated protein 4 | -0.046525 |
| MFF | mitochondrial fission factor | -0.046013 |
| SLC38A1 | solute carrier family 38, member 1 | -0.044519 |
| MYO6 | myosin VI | -0.0445031 |
| FOXP1 | forkhead box P1 | -0.0441711 |
| CDH13 | cadherin 13 | -0.0436369 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0427415 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0427382 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0426883 |
| CD44 | CD44 molecule (Indian blood group) | -0.0422706 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0415331 |
| SMYD3 | SET and MYND domain containing 3 | -0.0411717 |
| PTMA | prothymosin, alpha | -0.0406954 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0406657 |
| XPO1 | exportin 1 | -0.0399426 |
| PKM | pyruvate kinase, muscle | -0.0392138 |
| NDRG1 | N-myc downstream regulated 1 | -0.0389049 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0386134 |
| RBM39 | RNA binding motif protein 39 | -0.0383991 |
| PARD3 | par-3 family cell polarity regulator | -0.0382625 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0363375 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0357157 |
| MYO1E | myosin IE | -0.0355525 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.035156 |
| RPS19 | ribosomal protein S19 | -0.0350305 |
| CALU | calumenin | -0.0350256 |
| CTBP2 | C-terminal binding protein 2 | -0.0346531 |
| IGF2 | insulin-like growth factor 2 | -0.0341431 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0334017 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0331521 |
| CDK19 | cyclin-dependent kinase 19 | -0.0328825 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0327685 |
| ARRDC3 | arrestin domain containing 3 | -0.0327172 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.032678 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0326398 |
| LMO7 | LIM domain 7 | -0.032256 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0322434 |
| VCL | vinculin | -0.0320802 |
| STC1 | stanniocalcin 1 | -0.0313774 |
| GLG1 | golgi glycoprotein 1 | -0.030301 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0302681 |
| CLTC | clathrin, heavy chain (Hc) | -0.0302213 |
| RNF149 | ring finger protein 149 | -0.029964 |
| RPS12 | ribosomal protein S12 | -0.029204 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0289579 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0283384 |
| RPS3 | ribosomal protein S3 | -0.0269172 |
| RCOR1 | REST corepressor 1 | -0.0262519 |
