| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.242958 |
| NDRG1 | N-myc downstream regulated 1 | 0.104876 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0748139 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0712869 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0675302 |
| ANXA2 | annexin A2 | 0.0559421 |
| CD109 | CD109 molecule | 0.0534076 |
| ZNF292 | zinc finger protein 292 | 0.0445464 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0444328 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0402485 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0359032 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0350372 |
| IER3 | immediate early response 3 | 0.0337107 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0336799 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0335945 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0326118 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0322558 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0303074 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0300692 |
| ANGPTL4 | angiopoietin-like 4 | 0.0298597 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0292152 |
| ADM | adrenomedullin | 0.0290879 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0283963 |
| SBF2 | SET binding factor 2 | 0.0281655 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0278841 |
| FAM13A | family with sequence similarity 13, member A | 0.0274454 |
| EGFR | epidermal growth factor receptor | 0.0271993 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0271517 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0268443 |
| NAV2 | neuron navigator 2 | 0.0259208 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258592 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0258535 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0257043 |
| ANO6 | anoctamin 6 | 0.0256591 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0255101 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0251006 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0248445 |
| LMNA | lamin A/C | 0.0246728 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0243543 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0242199 |
| ZNF395 | zinc finger protein 395 | 0.0242021 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0240555 |
| MYOF | myoferlin | 0.0240432 |
| LOC112694756 | uncharaterized LOC112694756 | 0.023708 |
| CAVIN1 | caveolae associated protein 1 | 0.023541 |
| CCDC88A | coiled-coil domain containing 88A | 0.0234378 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0227765 |
| OGA | O-GlcNAcase | 0.0226402 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0220656 |
| GOLGB1 | golgin B1 | 0.0219608 |
| TMEM178B | transmembrane protein 178B | 0.0218684 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0218132 |
| MORF4L2 | mortality factor 4 like 2 | 0.0217897 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0217179 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0210618 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0210463 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0209698 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0206784 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0206777 |
| RRBP1 | ribosome binding protein 1 | 0.0205436 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.020264 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.020241 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0199387 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0197842 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0196135 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.019526 |
| LRRC23 | leucine rich repeat containing 23 | 0.0195195 |
| MEF2A | myocyte enhancer factor 2A | 0.0193249 |
| USP3 | ubiquitin specific peptidase 3 | 0.0188958 |
| RPL30 | ribosomal protein L30 | 0.0186613 |
| RTN4 | reticulon 4 | 0.0185956 |
| FLNA | filamin A, alpha | 0.0185566 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.018387 |
| SNX14 | sorting nexin 14 | 0.0181151 |
| CDC73 | cell division cycle 73 | 0.0180474 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0179128 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0178398 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0178214 |
| ARRDC3 | arrestin domain containing 3 | 0.0177625 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0177582 |
| SEC24D | SEC24 family member D | 0.0176888 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0175988 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0175021 |
| YEATS2 | YEATS domain containing 2 | 0.0174946 |
| PPP3CC | protein phosphatase 3, catalytic subunit, gamma isozyme | 0.0174411 |
| LOXL2 | lysyl oxidase-like 2 | 0.0174021 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.017357 |
| SCFD2 | sec1 family domain containing 2 | 0.0172079 |
| AFDN | afadin, adherens junction formation factor | 0.0171638 |
| HMGA2 | high mobility group AT-hook 2 | 0.0171236 |
| RASA3 | RAS p21 protein activator 3 | 0.0169463 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0169162 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0168127 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0167215 |
| CEP250 | centrosomal protein 250kDa | 0.0166832 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0165377 |
| SFXN1 | sideroflexin 1 | 0.016444 |
| AMZ1 | archaelysin family metallopeptidase 1 | 0.0161636 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0161214 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.016118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.199863 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196555 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.196195 |
| STC1 | stanniocalcin 1 | -0.136805 |
| VIM | vimentin | -0.134073 |
| TMSB10 | thymosin beta 10 | -0.133279 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.124414 |
| COL1A1 | collagen, type I, alpha 1 | -0.111813 |
| HLA-B | major histocompatibility complex, class I, B | -0.102727 |
| UBC | ubiquitin C | -0.0999916 |
| MT2A | metallothionein 2A | -0.0920634 |
| COL1A2 | collagen, type I, alpha 2 | -0.0887144 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.085558 |
| ENO1 | enolase 1, (alpha) | -0.078945 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0778179 |
| NRP1 | neuropilin 1 | -0.0768268 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0636466 |
| CDH13 | cadherin 13 | -0.0619697 |
| FTL | ferritin, light polypeptide | -0.057874 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0575107 |
| POTEF | POTE ankyrin domain family, member F | -0.0529605 |
| SP100 | SP100 nuclear antigen | -0.0513523 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0506565 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0499463 |
| MMP2 | matrix metallopeptidase 2 | -0.0497793 |
| PKM | pyruvate kinase, muscle | -0.048064 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0479898 |
| HLA-A | major histocompatibility complex, class I, A | -0.0478954 |
| RPS27A | ribosomal protein S27a | -0.046709 |
| CALU | calumenin | -0.0458886 |
| CALR | calreticulin | -0.0458362 |
| IFI44L | interferon-induced protein 44-like | -0.0438841 |
| TPM1 | tropomyosin 1 (alpha) | -0.043248 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0429556 |
| NAV1 | neuron navigator 1 | -0.0422465 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0411131 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0394635 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0394435 |
| MMP12 | matrix metallopeptidase 12 | -0.0386854 |
| H1-0 | H1.0 linker histone | -0.0384384 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0364303 |
| EGR1 | early growth response 1 | -0.0361679 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0358582 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0358342 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0351929 |
| IL1B | interleukin 1, beta | -0.0350587 |
| MX2 | MX dynamin-like GTPase 2 | -0.0338445 |
| ASPH | aspartate beta-hydroxylase | -0.0333402 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0331329 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0323513 |
| PGK1 | phosphoglycerate kinase 1 | -0.0318114 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0316703 |
| GLIS3 | GLIS family zinc finger 3 | -0.031643 |
| S100A6 | S100 calcium binding protein A6 | -0.0315865 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0311413 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0308384 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0307825 |
| ITGA11 | integrin, alpha 11 | -0.0300168 |
| PLSCR1 | phospholipid scramblase 1 | -0.0299141 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0298459 |
| MCL1 | myeloid cell leukemia 1 | -0.0289636 |
| DOCK5 | dedicator of cytokinesis 5 | -0.028885 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0287231 |
| VMP1 | vacuole membrane protein 1 | -0.0282619 |
| ERBIN | erbb2 interacting protein | -0.0281447 |
| OSMR | oncostatin M receptor | -0.0280781 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0280593 |
| C1R | complement component 1, r subcomponent | -0.0279883 |
| COL5A1 | collagen, type V, alpha 1 | -0.0279248 |
| INHBA | inhibin, beta A | -0.0277933 |
| CCNL1 | cyclin L1 | -0.0275674 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0273119 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0273053 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0271326 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0270317 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0269793 |
| RIGI | RNA sensor RIG-I | -0.0266774 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0265115 |
| ITGAV | integrin, alpha V | -0.0265061 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0265048 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0264511 |
| RPS19 | ribosomal protein S19 | -0.026419 |
| LDHA | lactate dehydrogenase A | -0.026077 |
| AHNAK | AHNAK nucleoprotein | -0.0260347 |
| FRMD4A | FERM domain containing 4A | -0.0258685 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0257782 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0255885 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0251031 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0249743 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0249472 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.024885 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0248091 |
| CST3 | cystatin C | -0.0246574 |
| SSH1 | slingshot protein phosphatase 1 | -0.0245431 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0241488 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.024101 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0238133 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0237125 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0236817 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0236135 |