Berbamine (dihydrochloride)_SNU-423 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Berbamine (dihydrochloride) perturbation in SNU-423 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Berbamine (dihydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FN1 fibronectin 1 0.3505
MYH9 myosin, heavy chain 9, non-muscle 0.142135
NAMPT nicotinamide phosphoribosyltransferase 0.117747
UGCG UDP-glucose ceramide glucosyltransferase 0.0927559
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0886651
ELL2 elongation factor, RNA polymerase II, 2 0.085299
SOD2 superoxide dismutase 2, mitochondrial 0.0845224
OGA O-GlcNAcase 0.0718447
ANXA2 annexin A2 0.0717044
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0696898
HLA-C major histocompatibility complex, class I, C 0.0696104
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0687659
ARRDC3 arrestin domain containing 3 0.0675552
TENT5A terminal nucleotidyltransferase 5A 0.0636243
CADM1 cell adhesion molecule 1 0.0577473
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0566398
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0565386
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0562327
EIF4H eukaryotic translation initiation factor 4H 0.0504446
ZNF292 zinc finger protein 292 0.0504144
VCAN versican 0.049703
OPTN optineurin 0.0469748
MYOF myoferlin 0.0463219
COL6A3 collagen, type VI, alpha 3 0.0460465
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0448491
IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 0.0446044
DST dystonin 0.0445484
RTN4 reticulon 4 0.0434604
NAV2 neuron navigator 2 0.0417958
USP9X ubiquitin specific peptidase 9, X-linked 0.0416817
BICC1 BicC family RNA binding protein 1 0.04141
WDFY1 WD repeat and FYVE domain containing 1 0.0413846
AFF4 AF4/FMR2 family, member 4 0.0413223
FNDC3B fibronectin type III domain containing 3B 0.0409932
BASP1 brain abundant, membrane attached signal protein 1 0.040766
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0402347
LOC112694756 uncharaterized LOC112694756 0.0393732
ANLN anillin, actin binding protein 0.0383939
TNIP1 TNFAIP3 interacting protein 1 0.0381493
MKI67 marker of proliferation Ki-67 0.037669
THBS1 thrombospondin 1 0.0376483
CEP250 centrosomal protein 250kDa 0.0372912
ATP13A3 ATPase type 13A3 0.0365054
FLNA filamin A, alpha 0.0360505
SMAD3 SMAD family member 3 0.0347138
ADM adrenomedullin 0.0336391
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0332949
EEF2 eukaryotic translation elongation factor 2 0.0331769
NPEPPS aminopeptidase puromycin sensitive 0.0329438
AFDN afadin, adherens junction formation factor 0.0328932
STAG2 stromal antigen 2 0.0324518
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.0320198
MXI1 MAX interactor 1, dimerization protein 0.0319974
UBA6 ubiquitin-like modifier activating enzyme 6 0.0313634
BRWD3 bromodomain and WD repeat domain containing 3 0.0309777
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.0309324
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0301401
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0301039
LAMP2 lysosomal-associated membrane protein 2 0.0296305
PRRC2A proline-rich coiled-coil 2A 0.0288523
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0286187
FRMD4A FERM domain containing 4A 0.0285139
COL8A1 collagen, type VIII, alpha 1 0.0276715
WDR45B WD repeat domain 45B 0.0274017
TUBB tubulin, beta class I 0.0271857
STARD4 StAR-related lipid transfer (START) domain containing 4 0.0271291
PHF21A PHD finger protein 21A 0.0270097
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0269991
CEP95 centrosomal protein 95kDa 0.0267573
BCLAF1 BCL2-associated transcription factor 1 0.0266817
NUP153 nucleoporin 153kDa 0.0264548
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0261279
RUNX2 runt-related transcription factor 2 0.0254992
CDK19 cyclin-dependent kinase 19 0.0254441
CKAP5 cytoskeleton associated protein 5 0.0253786
ZMIZ1 zinc finger, MIZ-type containing 1 0.0248861
LRRC7 leucine rich repeat containing 7 0.024836
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0247541
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0246432
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.024603
CSDE1 cold shock domain containing E1, RNA-binding 0.024448
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0243327
SPAG9 sperm associated antigen 9 0.0243082
TENM2 teneurin transmembrane protein 2 0.0242898
KDM3A lysine (K)-specific demethylase 3A 0.0242336
COL4A2 collagen, type IV, alpha 2 0.0240558
IL6ST interleukin 6 signal transducer 0.0236515
ZMYND8 zinc finger, MYND-type containing 8 0.0234405
SNX9 sorting nexin 9 0.0233791
SF3B1 splicing factor 3b, subunit 1, 155kDa 0.0232938
AHR aryl hydrocarbon receptor 0.0232807
AHNAK AHNAK nucleoprotein 0.0232556
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.0232096
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0230563
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0230106
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.0229485
SFTPA2 surfactant protein A2 0.0227264
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0227086
YEATS2 YEATS domain containing 2 0.0226493
DIAPH3 diaphanous-related formin 3 0.0225424

decreased expression

Symbol Name Standardized Value
MT2A metallothionein 2A -0.195661
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.173447
HLA-B major histocompatibility complex, class I, B -0.149611
TMSB10 thymosin beta 10 -0.128173
FTL ferritin, light polypeptide -0.110523
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough -0.102282
RPS6 ribosomal protein S6 -0.082328
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0787273
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0768443
HMGA2 high mobility group AT-hook 2 -0.0761287
INTS6 integrator complex subunit 6 -0.070387
HDAC9 histone deacetylase 9 -0.0677247
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0669131
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 -0.0660675
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0658936
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.065843
FTH1 ferritin, heavy polypeptide 1 -0.0586399
B2M beta-2-microglobulin -0.057403
CDH13 cadherin 13 -0.0563364
RPLP1 ribosomal protein, large, P1 -0.0547059
AKAP12 A kinase (PRKA) anchor protein 12 -0.0541325
ASPH aspartate beta-hydroxylase -0.0540316
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0524007
RPS19 ribosomal protein S19 -0.0484774
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.047004
RPL37A ribosomal protein L37a -0.0465643
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0465559
TPT1 tumor protein, translationally-controlled 1 -0.046531
RPL35A ribosomal protein L35a -0.0465044
RPS23 ribosomal protein S23 -0.0464904
VIM vimentin -0.0456273
RPL23 ribosomal protein L23 -0.0455476
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0453525
VEGFA vascular endothelial growth factor A -0.0452607
RAB7A RAB7A, member RAS oncogene family -0.0452375
RPLP2 ribosomal protein, large, P2 -0.0441938
KYNU kynureninase -0.0413882
IER3 immediate early response 3 -0.0399856
MT1X metallothionein 1X -0.0397665
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0393453
NAV1 neuron navigator 1 -0.0390299
LDHA lactate dehydrogenase A -0.0376908
RIGI RNA sensor RIG-I -0.0374823
RPS8 ribosomal protein S8 -0.0372122
RPL5 ribosomal protein L5 -0.0370982
RPL9 ribosomal protein L9 -0.0369064
ZBTB20 zinc finger and BTB domain containing 20 -0.0364172
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.0362717
CD44 CD44 molecule (Indian blood group) -0.036149
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.035922
RND3 Rho family GTPase 3 -0.0352605
EFNA5 ephrin-A5 -0.0351511
BPTF bromodomain PHD finger transcription factor -0.0342295
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0341677
TIMP2 TIMP metallopeptidase inhibitor 2 -0.0338703
ZCCHC7 zinc finger, CCHC domain containing 7 -0.0335127
RPL7A ribosomal protein L7a -0.0321832
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0320946
RPL31 ribosomal protein L31 -0.0317546
RPL28 ribosomal protein L28 -0.0311954
IFITM3 interferon induced transmembrane protein 3 -0.0307582
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0306213
RPS24 ribosomal protein S24 -0.030555
RPS13 ribosomal protein S13 -0.0303681
RPL36 ribosomal protein L36 -0.0302555
ISG15 ISG15 ubiquitin-like modifier -0.0299073
PDE4D phosphodiesterase 4D, cAMP-specific -0.0291981
RPS21 ribosomal protein S21 -0.0291381
S100A9 S100 calcium binding protein A9 -0.0286076
RPL19 ribosomal protein L19 -0.0284074
PTMA prothymosin, alpha -0.0280376
IFI6 interferon, alpha-inducible protein 6 -0.028033
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0279451
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A -0.0278469
AFF3 AF4/FMR2 family, member 3 -0.0275402
TBCA tubulin folding cofactor A -0.0274713
RPL38 ribosomal protein L38 -0.0273465
RPL26 ribosomal protein L26 -0.0271774
IARS1 isoleucyl-tRNA synthetase 1 -0.0270223
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0269677
C3 complement component 3 -0.0269619
NAP1L1 nucleosome assembly protein 1-like 1 -0.0269584
PTK2 protein tyrosine kinase 2 -0.0269078
HLA-A major histocompatibility complex, class I, A -0.0268624
RPS10 ribosomal protein S10 -0.0267295
RPS14 ribosomal protein S14 -0.0267205
IFIH1 interferon induced with helicase C domain 1 -0.0266871
RPS29 ribosomal protein S29 -0.0263985
RPL36A ribosomal protein L36a -0.0263922
WWOX WW domain containing oxidoreductase -0.0262123
SVIL supervillin -0.0260773
SP100 SP100 nuclear antigen -0.0260764
MAP1B microtubule-associated protein 1B -0.0260507
SIPA1L1 signal-induced proliferation-associated 1 like 1 -0.0258133
SEPTIN9 septin 9 -0.0255714
GOLGB1 golgin B1 -0.0254126
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -0.0253592
RAD51B RAD51 paralog B -0.0247603
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.0247296
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0247169