| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123806 |
| PKM | pyruvate kinase, muscle | 0.112266 |
| VIM | vimentin | 0.104631 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0728653 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0709463 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0662387 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0638158 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0632928 |
| RTN4 | reticulon 4 | 0.063268 |
| NAV2 | neuron navigator 2 | 0.0605939 |
| KIF5B | kinesin family member 5B | 0.0591982 |
| ENO1 | enolase 1, (alpha) | 0.0571212 |
| MSN | moesin | 0.0562266 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0558044 |
| POTEF | POTE ankyrin domain family, member F | 0.0533094 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0523546 |
| INSIG1 | insulin induced gene 1 | 0.0467635 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0457072 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0452703 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0430838 |
| RSF1 | remodeling and spacing factor 1 | 0.0428949 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0427528 |
| MKI67 | marker of proliferation Ki-67 | 0.0424053 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0422724 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0415979 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.040675 |
| PYGL | phosphorylase, glycogen, liver | 0.0405072 |
| LMO7 | LIM domain 7 | 0.0396774 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0379787 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0373602 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0371445 |
| MAP1B | microtubule-associated protein 1B | 0.0371429 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0370305 |
| NUP58 | nucleoporin 58 | 0.0364744 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0362966 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0362477 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0359127 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.03568 |
| FNIP1 | folliculin interacting protein 1 | 0.0353646 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0346612 |
| KIF2A | kinesin heavy chain member 2A | 0.0345493 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0344801 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0340533 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0338126 |
| ZNF292 | zinc finger protein 292 | 0.0331341 |
| NCKAP1 | NCK-associated protein 1 | 0.0326911 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0324284 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321178 |
| CENPF | centromere protein F, 350/400kDa | 0.0317722 |
| SEPTIN2 | septin 2 | 0.0306726 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0304763 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0302436 |
| CEP250 | centrosomal protein 250kDa | 0.0302432 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0302264 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0300967 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.029977 |
| PCBP2 | poly(rC) binding protein 2 | 0.0298139 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0295378 |
| CD44 | CD44 molecule (Indian blood group) | 0.0291159 |
| DIAPH3 | diaphanous-related formin 3 | 0.0284641 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.028456 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0283807 |
| USP3 | ubiquitin specific peptidase 3 | 0.0283363 |
| SET | SET nuclear proto-oncogene | 0.028283 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0281646 |
| TAOK1 | TAO kinase 1 | 0.0281074 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0279689 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0277451 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0277223 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0276588 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.027465 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0273934 |
| CEP295 | centrosomal protein 295kDa | 0.0273547 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0273488 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0270811 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0269654 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0269049 |
| CDCP1 | CUB domain containing protein 1 | 0.0268762 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0267545 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0265544 |
| GAN | gigaxonin | 0.0260885 |
| UTRN | utrophin | 0.0260136 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0257781 |
| TPI1 | triosephosphate isomerase 1 | 0.02569 |
| B2M | beta-2-microglobulin | 0.0256677 |
| PTMS | parathymosin | 0.0256645 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.025503 |
| CCDC88A | coiled-coil domain containing 88A | 0.0254757 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0254323 |
| ATXN1 | ataxin 1 | 0.0253957 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0253887 |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | 0.0250982 |
| NUCB2 | nucleobindin 2 | 0.0250929 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.025037 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0249898 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0248689 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0247154 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0246746 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0246442 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0240219 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.114266 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.106809 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0710551 |
| TMSB10 | thymosin beta 10 | -0.056587 |
| SMYD3 | SET and MYND domain containing 3 | -0.0536227 |
| OSMR | oncostatin M receptor | -0.050183 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0489418 |
| INTS6 | integrator complex subunit 6 | -0.0451868 |
| FUS | FUS RNA binding protein | -0.0434617 |
| GNAS | GNAS complex locus | -0.0420312 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0409132 |
| RPL4 | ribosomal protein L4 | -0.0408857 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0405776 |
| VCL | vinculin | -0.0397203 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0381454 |
| EGR1 | early growth response 1 | -0.0378835 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0375277 |
| RPLP1 | ribosomal protein, large, P1 | -0.0360964 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.035611 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0352801 |
| RPL35A | ribosomal protein L35a | -0.0351643 |
| RBM39 | RNA binding motif protein 39 | -0.0331903 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0327766 |
| AHNAK | AHNAK nucleoprotein | -0.0311739 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.031147 |
| RPL37 | ribosomal protein L37 | -0.0303277 |
| CEP290 | centrosomal protein 290kDa | -0.0302565 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.030068 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0298708 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0297961 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0295987 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0295088 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0294125 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0293478 |
| RDX | radixin | -0.029339 |
| LRRC49 | leucine rich repeat containing 49 | -0.0292444 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0291511 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.028974 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0286347 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0282235 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0280253 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0279118 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0278069 |
| DENND1A | DENN/MADD domain containing 1A | -0.0274963 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.027226 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0270124 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0269016 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0268049 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0266593 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0265992 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0262658 |
| NOP58 | NOP58 ribonucleoprotein | -0.026218 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0261502 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0259871 |
| ZNF644 | zinc finger protein 644 | -0.0257538 |
| NABP1 | nucleic acid binding protein 1 | -0.0256607 |
| STRBP | spermatid perinuclear RNA binding protein | -0.025166 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0248457 |
| NUP98 | nucleoporin 98kDa | -0.0247926 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0247323 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0247123 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0246295 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0244771 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0244273 |
| NMT1 | N-myristoyltransferase 1 | -0.0243485 |
| PDE8A | phosphodiesterase 8A | -0.0242709 |
| GPATCH8 | G patch domain containing 8 | -0.023943 |
| CYTH1 | cytohesin 1 | -0.0236176 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0234551 |
| IER3 | immediate early response 3 | -0.0232416 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | -0.023119 |
| H1-0 | H1.0 linker histone | -0.022996 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0228792 |
| MRC2 | mannose receptor, C type 2 | -0.0225352 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0225166 |
| HDLBP | high density lipoprotein binding protein | -0.0224757 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0224037 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0223407 |
| RPL30 | ribosomal protein L30 | -0.0220524 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0220027 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.021948 |
| CIRSR | corepressor of RBPJ and splicing regulator | -0.0218394 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0217553 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0216514 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0215199 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0213485 |
| SUMF1 | sulfatase modifying factor 1 | -0.0212645 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0212073 |
| JMJD1C | jumonji domain containing 1C | -0.0210702 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.021026 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.020928 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0208435 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0208318 |
| RPL19 | ribosomal protein L19 | -0.0207706 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0206509 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B | -0.020602 |
| RPL6 | ribosomal protein L6 | -0.0205599 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0204346 |
| FMNL2 | formin-like 2 | -0.02037 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0202618 |