| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.115384 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.104024 |
| ANXA1 | annexin A1 | 0.098018 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0932529 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0853751 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0763854 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0756009 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0747994 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0737463 |
| RUNX2 | runt-related transcription factor 2 | 0.0697129 |
| LAMC2 | laminin, gamma 2 | 0.0680745 |
| LMO7 | LIM domain 7 | 0.064306 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0624252 |
| TXNRD1 | thioredoxin reductase 1 | 0.0617136 |
| GOLGA4 | golgin A4 | 0.0601709 |
| FAT1 | FAT atypical cadherin 1 | 0.0575676 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0528613 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0503789 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.049487 |
| SERINC5 | serine incorporator 5 | 0.0482824 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0478982 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0477992 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0458092 |
| FOXO1 | forkhead box O1 | 0.045409 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.044715 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0446456 |
| SLTM | SAFB-like, transcription modulator | 0.04417 |
| RNF145 | ring finger protein 145 | 0.0436356 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0399843 |
| CLTC | clathrin, heavy chain (Hc) | 0.0396591 |
| WDR43 | WD repeat domain 43 | 0.0390545 |
| LDHA | lactate dehydrogenase A | 0.0370672 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.036466 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0364336 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.036422 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0363229 |
| COG5 | component of oligomeric golgi complex 5 | 0.0362661 |
| MATR3 | matrin 3 | 0.0358847 |
| NEK7 | NIMA-related kinase 7 | 0.0357418 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0356855 |
| MED13L | mediator complex subunit 13-like | 0.0355404 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.035521 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0354721 |
| KITLG | KIT ligand | 0.0351335 |
| HM13 | histocompatibility (minor) 13 | 0.0350407 |
| USP6NL | USP6 N-terminal like | 0.0344811 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0344123 |
| USP34 | ubiquitin specific peptidase 34 | 0.0339382 |
| RBM25 | RNA binding motif protein 25 | 0.0339016 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0334203 |
| TJP1 | tight junction protein 1 | 0.0333002 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0331905 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0327249 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0323036 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0322402 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0318705 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0317237 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0315848 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0312257 |
| TOP1 | topoisomerase (DNA) I | 0.0308824 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0308641 |
| DUSP4 | dual specificity phosphatase 4 | 0.0307739 |
| ATP11B | ATPase, class VI, type 11B | 0.0307234 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0306351 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304046 |
| MED13 | mediator complex subunit 13 | 0.0302926 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0302858 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0302836 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.03009 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.030082 |
| RPL11 | ribosomal protein L11 | 0.0296612 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.029627 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0286639 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0282017 |
| NF1 | neurofibromin 1 | 0.0281613 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0279147 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278641 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0278082 |
| ATP11A | ATPase, class VI, type 11A | 0.027698 |
| FHL2 | four and a half LIM domains 2 | 0.0275515 |
| IPO7 | importin 7 | 0.0275183 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.027464 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0272236 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0271739 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0270115 |
| NFIA | nuclear factor I/A | 0.0267867 |
| YTHDC1 | YTH domain containing 1 | 0.0267458 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.0267374 |
| PKM | pyruvate kinase, muscle | 0.0265055 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0263762 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0260372 |
| ITGA6 | integrin, alpha 6 | 0.0256126 |
| RPL21 | ribosomal protein L21 | 0.0254607 |
| DIAPH1 | diaphanous-related formin 1 | 0.0252398 |
| RFX7 | regulatory factor X, 7 | 0.0251583 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0250911 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0249133 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0248592 |
| EREG | epiregulin | 0.024777 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0246641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.189759 |
| HMGA2 | high mobility group AT-hook 2 | -0.173895 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0942844 |
| IER3 | immediate early response 3 | -0.093639 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0850347 |
| TMSB10 | thymosin beta 10 | -0.077792 |
| FERMT1 | fermitin family member 1 | -0.0747603 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0699956 |
| ACTG1 | actin gamma 1 | -0.0679401 |
| LAMA4 | laminin, alpha 4 | -0.065956 |
| RAD51B | RAD51 paralog B | -0.0628437 |
| RPS6 | ribosomal protein S6 | -0.0582934 |
| AHNAK | AHNAK nucleoprotein | -0.0565067 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.054414 |
| EGR1 | early growth response 1 | -0.0524114 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0512364 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0509681 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0476175 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0467649 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0450744 |
| RPL35A | ribosomal protein L35a | -0.0442204 |
| MKI67 | marker of proliferation Ki-67 | -0.0432376 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427262 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0426115 |
| EHBP1 | EH domain binding protein 1 | -0.0422451 |
| EZR | ezrin | -0.04215 |
| FHIT | fragile histidine triad | -0.0418581 |
| RPS19 | ribosomal protein S19 | -0.0401161 |
| CUX1 | cut-like homeobox 1 | -0.0396914 |
| RPS29 | ribosomal protein S29 | -0.0395102 |
| S100A6 | S100 calcium binding protein A6 | -0.0363337 |
| RPL4 | ribosomal protein L4 | -0.0342227 |
| BMP4 | bone morphogenetic protein 4 | -0.0334186 |
| RPL19 | ribosomal protein L19 | -0.0332195 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0330875 |
| TUBB | tubulin, beta class I | -0.0328854 |
| GPC5 | glypican 5 | -0.0327781 |
| RPS24 | ribosomal protein S24 | -0.0327675 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0322012 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0313116 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0313011 |
| RPL36A | ribosomal protein L36a | -0.0312074 |
| ITGB4 | integrin, beta 4 | -0.0307778 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0306746 |
| CCDC200 | coiled-coil domain containing 200 | -0.030647 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.030577 |
| SDC4 | syndecan 4 | -0.0301032 |
| RPS27A | ribosomal protein S27a | -0.029822 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0296955 |
| RPLP2 | ribosomal protein, large, P2 | -0.0292773 |
| RRM2 | ribonucleotide reductase M2 | -0.0292538 |
| RPL31 | ribosomal protein L31 | -0.0291987 |
| TENM3 | teneurin transmembrane protein 3 | -0.0289268 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0275201 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0275142 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0270134 |
| CD9 | CD9 molecule | -0.0269402 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0269275 |
| S100A9 | S100 calcium binding protein A9 | -0.0268536 |
| WWOX | WW domain containing oxidoreductase | -0.0265583 |
| RPL23 | ribosomal protein L23 | -0.0259389 |
| HIP1 | huntingtin interacting protein 1 | -0.0256592 |
| PLEC | plectin | -0.0256184 |
| FOXP1 | forkhead box P1 | -0.0244816 |
| RPS5 | ribosomal protein S5 | -0.0243644 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0243584 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0238608 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0236807 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0235065 |
| RPS25 | ribosomal protein S25 | -0.023397 |
| RCOR1 | REST corepressor 1 | -0.0230844 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.023041 |
| RPL12 | ribosomal protein L12 | -0.0230123 |
| CMIP | c-Maf inducing protein | -0.0229325 |
| RPS8 | ribosomal protein S8 | -0.0229004 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.0227279 |
| TUT4 | terminal uridylyl transferase 4 | -0.0226908 |
| TMEM123 | transmembrane protein 123 | -0.0224933 |
| RPS27 | ribosomal protein S27 | -0.0219592 |
| RPS21 | ribosomal protein S21 | -0.0218095 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0217851 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0216768 |
| RPL32 | ribosomal protein L32 | -0.02159 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0215875 |
| RPL15 | ribosomal protein L15 | -0.0211731 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0211377 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0209774 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0209366 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0209256 |
| ABR | active BCR-related | -0.0208227 |
| MTAP | methylthioadenosine phosphorylase | -0.0206015 |
| DEK | DEK proto-oncogene | -0.0205438 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0204652 |
| FRMD8 | FERM domain containing 8 | -0.0203415 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0202036 |
| FTL | ferritin, light polypeptide | -0.0199383 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0199325 |
| RPS13 | ribosomal protein S13 | -0.0198774 |
| EXOC4 | exocyst complex component 4 | -0.019846 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | -0.0198243 |
