| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine (dihydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine (dihydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.109727 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.106891 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.105004 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0835534 |
| FAM13A | family with sequence similarity 13, member A | 0.0787871 |
| VIM | vimentin | 0.0787858 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0733216 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0568444 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.056816 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0567149 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0530987 |
| NAV2 | neuron navigator 2 | 0.0513164 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0503509 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0494372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0473226 |
| MMP12 | matrix metallopeptidase 12 | 0.0461846 |
| DST | dystonin | 0.0459766 |
| ADM | adrenomedullin | 0.0452686 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0451562 |
| GOLGA4 | golgin A4 | 0.0451408 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0449517 |
| HELZ | helicase with zinc finger | 0.044323 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0423621 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.039617 |
| CALU | calumenin | 0.0392749 |
| FMNL2 | formin-like 2 | 0.0378733 |
| ZNF292 | zinc finger protein 292 | 0.0372023 |
| B2M | beta-2-microglobulin | 0.0359485 |
| PRELID2 | PRELI domain containing 2 | 0.0358404 |
| ENO1 | enolase 1, (alpha) | 0.0357957 |
| CALR | calreticulin | 0.0356115 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0343257 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0341521 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.033163 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.032744 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0321923 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.031541 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0313028 |
| NGLY1 | N-glycanase 1 | 0.0310317 |
| MYOF | myoferlin | 0.0303216 |
| CANX | calnexin | 0.0298106 |
| FNIP1 | folliculin interacting protein 1 | 0.0297838 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0294936 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0293873 |
| PCBP2 | poly(rC) binding protein 2 | 0.029319 |
| NUP58 | nucleoporin 58 | 0.0291524 |
| OGA | O-GlcNAcase | 0.0287497 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0272368 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.027177 |
| YEATS2 | YEATS domain containing 2 | 0.0269287 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0268283 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0261598 |
| NDRG1 | N-myc downstream regulated 1 | 0.0261289 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0259457 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0257455 |
| XPO1 | exportin 1 | 0.0255687 |
| ANXA5 | annexin A5 | 0.0251276 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0251099 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0247985 |
| ZNF638 | zinc finger protein 638 | 0.0246203 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0245461 |
| MED13L | mediator complex subunit 13-like | 0.0243917 |
| RPL3 | ribosomal protein L3 | 0.0241284 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0239762 |
| TMEM165 | transmembrane protein 165 | 0.0234343 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0234031 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233532 |
| HMGB2 | high mobility group box 2 | 0.0232014 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0231559 |
| LDHA | lactate dehydrogenase A | 0.0230823 |
| CENPF | centromere protein F, 350/400kDa | 0.0230613 |
| TNS1 | tensin 1 | 0.0230364 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0230205 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0224545 |
| ATXN1 | ataxin 1 | 0.0224214 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0222785 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0222401 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0215368 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0215249 |
| RNF150 | ring finger protein 150 | 0.0214512 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0214084 |
| HDAC9 | histone deacetylase 9 | 0.0212686 |
| SPAG9 | sperm associated antigen 9 | 0.0212635 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0212264 |
| INSIG1 | insulin induced gene 1 | 0.0211079 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0210204 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.020451 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0202143 |
| NBAS | neuroblastoma amplified sequence | 0.0201574 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.0201046 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0201009 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0200549 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0199619 |
| PLEC | plectin | 0.0199358 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0198838 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0195394 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0195054 |
| RTN4 | reticulon 4 | 0.0194017 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0191963 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0188224 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.197835 |
| INHBA | inhibin, beta A | -0.141535 |
| HMGA2 | high mobility group AT-hook 2 | -0.138815 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.114875 |
| EXT1 | exostosin glycosyltransferase 1 | -0.103167 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0902131 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0868534 |
| MMP1 | matrix metallopeptidase 1 | -0.0724412 |
| CD44 | CD44 molecule (Indian blood group) | -0.069704 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0697003 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0684386 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0652465 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.061695 |
| HLA-B | major histocompatibility complex, class I, B | -0.0592996 |
| COL1A1 | collagen, type I, alpha 1 | -0.051678 |
| EMP1 | epithelial membrane protein 1 | -0.0515913 |
| COL5A3 | collagen, type V, alpha 3 | -0.0514467 |
| MYO10 | myosin X | -0.0510542 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0497123 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0492023 |
| VCL | vinculin | -0.045224 |
| NAV1 | neuron navigator 1 | -0.0434228 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0432775 |
| FRMD4A | FERM domain containing 4A | -0.0402313 |
| TMSB10 | thymosin beta 10 | -0.0397135 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0391571 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.038766 |
| EGFR | epidermal growth factor receptor | -0.0377955 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0377482 |
| RAI14 | retinoic acid induced 14 | -0.0375719 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0373369 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0360779 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0355459 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0348309 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0343997 |
| OSMR | oncostatin M receptor | -0.0343647 |
| CLMP | CXADR-like membrane protein | -0.0341842 |
| FTL | ferritin, light polypeptide | -0.0340968 |
| CALD1 | caldesmon 1 | -0.0336744 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0336624 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0336461 |
| MT2A | metallothionein 2A | -0.0332785 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0332596 |
| KIAA1549L | KIAA1549-like | -0.0325102 |
| ACTG1 | actin gamma 1 | -0.0324052 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0319138 |
| CAVIN1 | caveolae associated protein 1 | -0.030406 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0297729 |
| VMP1 | vacuole membrane protein 1 | -0.0292118 |
| GLIS3 | GLIS family zinc finger 3 | -0.0287348 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0284188 |
| DIAPH2 | diaphanous-related formin 2 | -0.0282232 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.027661 |
| STC1 | stanniocalcin 1 | -0.0276319 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0276242 |
| PRRX1 | paired related homeobox 1 | -0.0270507 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0267494 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0256346 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0255603 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.0250621 |
| ATP13A3 | ATPase type 13A3 | -0.024881 |
| H1-0 | H1.0 linker histone | -0.0247819 |
| PDE8A | phosphodiesterase 8A | -0.0245485 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0240088 |
| LOC112694756 | uncharaterized LOC112694756 | -0.023912 |
| EGR1 | early growth response 1 | -0.0237732 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0237219 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0236837 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0235995 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0235726 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.023534 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0233984 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0233128 |
| OXR1 | oxidation resistance 1 | -0.0223652 |
| DNER | delta/notch-like EGF repeat containing | -0.0218224 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0215238 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0215079 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0212735 |
| MAP1B | microtubule-associated protein 1B | -0.0207393 |
| CCND1 | cyclin D1 | -0.0205115 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.0203048 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0200613 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.019941 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0196676 |
| SEPTIN11 | septin 11 | -0.0195355 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0192518 |
| RPL35A | ribosomal protein L35a | -0.0191935 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0189776 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0189459 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0186348 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.018466 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0181202 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0176823 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0171823 |
| PALLD | palladin, cytoskeletal associated protein | -0.0170501 |
| TPM4 | tropomyosin 4 | -0.0169831 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0168967 |
| CCDC102B | coiled-coil domain containing 102B | -0.0168775 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0168178 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0163511 |
