| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.503096 |
| PODXL | podocalyxin-like | 0.202325 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.169286 |
| TMSB10 | thymosin beta 10 | 0.119123 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.117703 |
| AHNAK | AHNAK nucleoprotein | 0.113499 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.108221 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0959774 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0832277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.079697 |
| NAV1 | neuron navigator 1 | 0.0775448 |
| AUTS2 | autism susceptibility candidate 2 | 0.0751905 |
| HLA-B | major histocompatibility complex, class I, B | 0.0739505 |
| NAV2 | neuron navigator 2 | 0.065599 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0655195 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0597331 |
| CSTB | cystatin B (stefin B) | 0.0574373 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0567877 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0561251 |
| FLNB | filamin B, beta | 0.0529796 |
| PLEC | plectin | 0.051371 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0505854 |
| LOXL2 | lysyl oxidase-like 2 | 0.0501475 |
| MSI2 | musashi RNA-binding protein 2 | 0.0493847 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0477772 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0474779 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.044924 |
| SQSTM1 | sequestosome 1 | 0.0447564 |
| HLA-A | major histocompatibility complex, class I, A | 0.0438003 |
| EGFR | epidermal growth factor receptor | 0.0435347 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0428365 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0425614 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0420707 |
| C1D | C1D nuclear receptor corepressor | 0.0411808 |
| MAP1B | microtubule-associated protein 1B | 0.0403113 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0397914 |
| RND3 | Rho family GTPase 3 | 0.0384416 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0370456 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.037005 |
| COPA | coatomer protein complex, subunit alpha | 0.0369734 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0368656 |
| FBN1 | fibrillin 1 | 0.0366075 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0365328 |
| CDH13 | cadherin 13 | 0.0356276 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.033797 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0337566 |
| MEIS2 | Meis homeobox 2 | 0.0331516 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0322357 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0313319 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0312464 |
| RNF169 | ring finger protein 169 | 0.0306343 |
| VEGFC | vascular endothelial growth factor C | 0.0302038 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0296461 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0294616 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0293383 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0290217 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0289705 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0285138 |
| CD109 | CD109 molecule | 0.0283724 |
| HLA-C | major histocompatibility complex, class I, C | 0.0283531 |
| FRMD4A | FERM domain containing 4A | 0.0283293 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0283292 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0281142 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0278767 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.027537 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0272711 |
| JUN | jun proto-oncogene | 0.0271918 |
| INSIG1 | insulin induced gene 1 | 0.0269471 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0269265 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0269136 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0267456 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0267443 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0266839 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0265859 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0262717 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0262037 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0261889 |
| AFDN | afadin, adherens junction formation factor | 0.025937 |
| MMP12 | matrix metallopeptidase 12 | 0.0259034 |
| SEPTIN9 | septin 9 | 0.025765 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0256344 |
| GOLGA2 | golgin A2 | 0.0255537 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0254995 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0250828 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0249273 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0248015 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0246952 |
| FLNA | filamin A, alpha | 0.0246148 |
| ACTG1 | actin gamma 1 | 0.024585 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0244977 |
| COL5A1 | collagen, type V, alpha 1 | 0.024453 |
| TPM1 | tropomyosin 1 (alpha) | 0.0244529 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0242823 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.024206 |
| RNF213 | ring finger protein 213 | 0.0241884 |
| BCL2L1 | BCL2-like 1 | 0.0241484 |
| PGK1 | phosphoglycerate kinase 1 | 0.0234896 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0229975 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0229886 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0229246 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.154189 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.13129 |
| CD44 | CD44 molecule (Indian blood group) | -0.126352 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.083925 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0817396 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0809394 |
| PLAT | plasminogen activator, tissue | -0.074774 |
| MT2A | metallothionein 2A | -0.072546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0698021 |
| COL3A1 | collagen, type III, alpha 1 | -0.0641013 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0635992 |
| S100A10 | S100 calcium binding protein A10 | -0.0520391 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0510062 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.050719 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0501973 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0479793 |
| COL5A2 | collagen, type V, alpha 2 | -0.0432283 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0408827 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0402313 |
| STC1 | stanniocalcin 1 | -0.0402177 |
| RPS2 | ribosomal protein S2 | -0.0401816 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0387986 |
| LOX | lysyl oxidase | -0.0380573 |
| SEPTIN7 | septin 7 | -0.035846 |
| MYOF | myoferlin | -0.0347033 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0338313 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0332928 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0323312 |
| ASPH | aspartate beta-hydroxylase | -0.0313229 |
| XPO1 | exportin 1 | -0.0308586 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0296498 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0287074 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0283539 |
| CENPF | centromere protein F, 350/400kDa | -0.0282927 |
| CLTC | clathrin, heavy chain (Hc) | -0.0277847 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0271783 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0261396 |
| CANX | calnexin | -0.0260787 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0260477 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0251526 |
| IL6ST | interleukin 6 signal transducer | -0.0249944 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0248997 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0245572 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.024541 |
| RAI14 | retinoic acid induced 14 | -0.0239142 |
| LDHA | lactate dehydrogenase A | -0.0236394 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0233448 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0233194 |
| UBXN4 | UBX domain protein 4 | -0.0230965 |
| B2M | beta-2-microglobulin | -0.0229347 |
| LRRC17 | leucine rich repeat containing 17 | -0.0227639 |
| PRKD3 | protein kinase D3 | -0.0226308 |
| SVIL | supervillin | -0.0225449 |
| NEK7 | NIMA-related kinase 7 | -0.0224392 |
| FN1 | fibronectin 1 | -0.0221061 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0220317 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -0.0220123 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0212792 |
| HMGB2 | high mobility group box 2 | -0.0209923 |
| ZNF217 | zinc finger protein 217 | -0.0207998 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0206137 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0204569 |
| MKI67 | marker of proliferation Ki-67 | -0.0201914 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0201562 |
| H2AC6 | H2A clustered histone 6 | -0.0199852 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0198099 |
| CAVIN1 | caveolae associated protein 1 | -0.019721 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0196903 |
| S100A4 | S100 calcium binding protein A4 | -0.0196506 |
| MB21D2 | Mab-21 domain containing 2 | -0.0196282 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0193853 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0190692 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0188634 |
| GOLT1B | golgi transport 1B | -0.018734 |
| DSPP | dentin sialophosphoprotein | -0.0184963 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0184582 |
| POTEF | POTE ankyrin domain family, member F | -0.0182284 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0181072 |
| VDAC1 | voltage-dependent anion channel 1 | -0.018103 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.017981 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.017769 |
| CYTH3 | cytohesin 3 | -0.0177509 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0176021 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0172607 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0172583 |
| ANLN | anillin, actin binding protein | -0.0171259 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0170903 |
| SERINC1 | serine incorporator 1 | -0.0170718 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0170635 |
| LAMB1 | laminin, beta 1 | -0.0168269 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0165807 |
| FAM13B | family with sequence similarity 13, member B | -0.0163573 |
| MTDH | metadherin | -0.0161796 |
| CDC73 | cell division cycle 73 | -0.0161411 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0160971 |
| GOLIM4 | golgi integral membrane protein 4 | -0.0160614 |
| TLN1 | talin 1 | -0.0160147 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0159871 |
| RPL37A | ribosomal protein L37a | -0.0159742 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0159453 |
