| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.320664 |
| NDRG1 | N-myc downstream regulated 1 | 0.159372 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.148807 |
| FN1 | fibronectin 1 | 0.145385 |
| COL6A3 | collagen, type VI, alpha 3 | 0.14045 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.117038 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.112657 |
| VEGFA | vascular endothelial growth factor A | 0.112624 |
| PLEC | plectin | 0.105151 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.101995 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0945083 |
| MT2A | metallothionein 2A | 0.09313 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0676814 |
| PTK2 | protein tyrosine kinase 2 | 0.0657881 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.062433 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0601022 |
| COL7A1 | collagen, type VII, alpha 1 | 0.059422 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0594143 |
| SMAD3 | SMAD family member 3 | 0.0593506 |
| PRELID2 | PRELI domain containing 2 | 0.0591544 |
| NAV2 | neuron navigator 2 | 0.0584442 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0578987 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0554689 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0549636 |
| GOLGA4 | golgin A4 | 0.0537144 |
| CDH13 | cadherin 13 | 0.0534584 |
| ATXN1 | ataxin 1 | 0.0533784 |
| PDE10A | phosphodiesterase 10A | 0.0520079 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0512296 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0511353 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0497533 |
| HLA-B | major histocompatibility complex, class I, B | 0.0491349 |
| LOXL2 | lysyl oxidase-like 2 | 0.0488751 |
| COL5A1 | collagen, type V, alpha 1 | 0.0488184 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0473318 |
| NAV1 | neuron navigator 1 | 0.0466746 |
| FMNL2 | formin-like 2 | 0.0462516 |
| ATP13A3 | ATPase type 13A3 | 0.0436711 |
| TNS1 | tensin 1 | 0.0409909 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0380454 |
| VMP1 | vacuole membrane protein 1 | 0.0376779 |
| EGFR | epidermal growth factor receptor | 0.0374597 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0367499 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0356735 |
| TMEM165 | transmembrane protein 165 | 0.0351527 |
| CMIP | c-Maf inducing protein | 0.0347407 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0340645 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0340238 |
| MSN | moesin | 0.0338941 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0333488 |
| AXL | AXL receptor tyrosine kinase | 0.0330976 |
| MYO9B | myosin IXB | 0.0329822 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0328722 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0326065 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0323342 |
| OGA | O-GlcNAcase | 0.0320121 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0318407 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0318015 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0316847 |
| CABIN1 | calcineurin binding protein 1 | 0.0306698 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0305448 |
| CCNY | cyclin Y | 0.0302233 |
| STC1 | stanniocalcin 1 | 0.0301566 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0300758 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0299822 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0297608 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0295243 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0294159 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0294041 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0292771 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0292687 |
| HLA-A | major histocompatibility complex, class I, A | 0.0291271 |
| ACTG1 | actin gamma 1 | 0.029085 |
| NOTCH2 | notch 2 | 0.0290737 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0289449 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0281939 |
| ZNF292 | zinc finger protein 292 | 0.0281676 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0281238 |
| BRD4 | bromodomain containing 4 | 0.0279803 |
| FAM219A | family with sequence similarity 219, member A | 0.0276069 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0275467 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0274575 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0270965 |
| COPA | coatomer protein complex, subunit alpha | 0.0270726 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0269652 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0268637 |
| FLNA | filamin A, alpha | 0.0267187 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0264268 |
| FLNB | filamin B, beta | 0.0263515 |
| EFNA5 | ephrin-A5 | 0.0263263 |
| ECE1 | endothelin converting enzyme 1 | 0.0263078 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | 0.025998 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0258278 |
| SON | SON DNA binding protein | 0.0258146 |
| COG5 | component of oligomeric golgi complex 5 | 0.0257307 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0255542 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0254789 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0254669 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0253482 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0252872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.207412 |
| VIM | vimentin | -0.155414 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.131357 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.120022 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.106478 |
| CD44 | CD44 molecule (Indian blood group) | -0.103178 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0942348 |
| LOX | lysyl oxidase | -0.0855567 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.079622 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0737132 |
| SQLE | squalene epoxidase | -0.0732387 |
| IER3 | immediate early response 3 | -0.0693619 |
| COL1A1 | collagen, type I, alpha 1 | -0.0563818 |
| FTL | ferritin, light polypeptide | -0.0541474 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0539491 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0484771 |
| INSIG1 | insulin induced gene 1 | -0.0471507 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0417099 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0392475 |
| LDHA | lactate dehydrogenase A | -0.0390611 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0384795 |
| INHBA | inhibin, beta A | -0.0382497 |
| ANXA2 | annexin A2 | -0.0378714 |
| PALLD | palladin, cytoskeletal associated protein | -0.0361142 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0360237 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0335863 |
| IL6ST | interleukin 6 signal transducer | -0.032905 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0320524 |
| S100A10 | S100 calcium binding protein A10 | -0.0317421 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0305469 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0304604 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0298563 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0293748 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0288594 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0287722 |
| ASPH | aspartate beta-hydroxylase | -0.0281743 |
| MAP1B | microtubule-associated protein 1B | -0.0273919 |
| CANX | calnexin | -0.0269971 |
| LIPG | lipase, endothelial | -0.0269065 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0264413 |
| H1-0 | H1.0 linker histone | -0.0263868 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.026057 |
| KLF6 | Kruppel-like factor 6 | -0.0256756 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0255827 |
| OSMR | oncostatin M receptor | -0.0255665 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0246606 |
| VCL | vinculin | -0.0242691 |
| TMSB4X | thymosin beta 4, X-linked | -0.0235016 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0233087 |
| TKT | transketolase | -0.0227575 |
| TMEM123 | transmembrane protein 123 | -0.0221433 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0220821 |
| CALD1 | caldesmon 1 | -0.0219476 |
| CNTN5 | contactin 5 | -0.0219409 |
| FDPS | farnesyl diphosphate synthase | -0.0213055 |
| ENO1 | enolase 1, (alpha) | -0.021233 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0212313 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | -0.0209907 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0204896 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0203276 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0201411 |
| TENM1 | teneurin transmembrane protein 1 | -0.0198063 |
| SOAT2 | sterol O-acyltransferase 2 | -0.0191246 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0186056 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0185613 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -0.0185534 |
| CCND1 | cyclin D1 | -0.018215 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0180014 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0175986 |
| EGR1 | early growth response 1 | -0.0173987 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0172772 |
| RPL12 | ribosomal protein L12 | -0.0172426 |
| RTN4 | reticulon 4 | -0.0171536 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.016612 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0162956 |
| S100A6 | S100 calcium binding protein A6 | -0.0161779 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0160819 |
| ARF1 | ADP-ribosylation factor 1 | -0.0158407 |
| YBX1 | Y box binding protein 1 | -0.0155608 |
| TUBA1B | tubulin, alpha 1b | -0.0154687 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.0154311 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0154155 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0153502 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.015221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0151396 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0150735 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0148985 |
| TXNRD1 | thioredoxin reductase 1 | -0.0147805 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0144762 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.014425 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0143044 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0142442 |
| TAOK1 | TAO kinase 1 | -0.0139054 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0138392 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0138016 |
| ERBIN | erbb2 interacting protein | -0.0137724 |
| RPL35A | ribosomal protein L35a | -0.0137011 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0135837 |
| NREP | neuronal regeneration related protein | -0.0130646 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0130596 |
