| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.15239 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.129555 |
| TXNRD1 | thioredoxin reductase 1 | 0.120611 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.105133 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0992809 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0926407 |
| RPS6 | ribosomal protein S6 | 0.0828789 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.078011 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0752638 |
| RPL35A | ribosomal protein L35a | 0.0722536 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0707104 |
| MT2A | metallothionein 2A | 0.0701902 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0699724 |
| EZR | ezrin | 0.0696317 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0687592 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0660343 |
| RAI1 | retinoic acid induced 1 | 0.0640642 |
| RUNX1 | runt-related transcription factor 1 | 0.0636496 |
| PGK1 | phosphoglycerate kinase 1 | 0.0585692 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0559421 |
| EGR1 | early growth response 1 | 0.0525714 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0521718 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0520158 |
| TMEM41B | transmembrane protein 41B | 0.0497105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0481735 |
| YEATS2 | YEATS domain containing 2 | 0.0464868 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0463213 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.04622 |
| TMSB4X | thymosin beta 4, X-linked | 0.046135 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0455231 |
| PODXL | podocalyxin-like | 0.0441696 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0436552 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0426399 |
| RPS19 | ribosomal protein S19 | 0.0425836 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0417033 |
| MAP4 | microtubule-associated protein 4 | 0.0402233 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0397231 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.038286 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0376042 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0375598 |
| CENPF | centromere protein F, 350/400kDa | 0.0374575 |
| ACTG1 | actin gamma 1 | 0.0370613 |
| JMJD1C | jumonji domain containing 1C | 0.0362146 |
| RPL19 | ribosomal protein L19 | 0.0361888 |
| SEC24A | SEC24 family member A | 0.0357673 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0353894 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0349921 |
| RTN4 | reticulon 4 | 0.0349796 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0348762 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0348246 |
| PYGB | phosphorylase, glycogen; brain | 0.0335855 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0333579 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.033034 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0329652 |
| CAPRIN2 | caprin family member 2 | 0.0325917 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0320561 |
| NAV2 | neuron navigator 2 | 0.0318301 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0314306 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0313102 |
| TPM4 | tropomyosin 4 | 0.0310495 |
| LOXL2 | lysyl oxidase-like 2 | 0.0308894 |
| FTL | ferritin, light polypeptide | 0.0308031 |
| SETD5 | SET domain containing 5 | 0.0307182 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0304712 |
| VEGFC | vascular endothelial growth factor C | 0.0304486 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0296691 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0296148 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0295099 |
| CCNL1 | cyclin L1 | 0.029327 |
| RPL11 | ribosomal protein L11 | 0.0292715 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0291608 |
| LPIN1 | lipin 1 | 0.0291259 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0289598 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 0.0288041 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0287901 |
| NPAS2 | neuronal PAS domain protein 2 | 0.028647 |
| TUBB6 | tubulin, beta 6 class V | 0.0273619 |
| SNX9 | sorting nexin 9 | 0.0273115 |
| ETNK1 | ethanolamine kinase 1 | 0.0271081 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0267722 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0266824 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0266483 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0262365 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0261667 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0261644 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0261161 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0260846 |
| CDK19 | cyclin-dependent kinase 19 | 0.0260541 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.026052 |
| GOLGA4 | golgin A4 | 0.0258641 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0258069 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0257841 |
| HDLBP | high density lipoprotein binding protein | 0.0257128 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0256539 |
| SFTPA2 | surfactant protein A2 | 0.0254058 |
| FDPS | farnesyl diphosphate synthase | 0.0251532 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0250631 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0248596 |
| RPS23 | ribosomal protein S23 | 0.0248471 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0241587 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.173965 |
| VIM | vimentin | -0.16806 |
| TP63 | tumor protein p63 | -0.165289 |
| UBC | ubiquitin C | -0.149126 |
| CD44 | CD44 molecule (Indian blood group) | -0.0999613 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0948073 |
| RPS27A | ribosomal protein S27a | -0.0894333 |
| ENO1 | enolase 1, (alpha) | -0.0841676 |
| PRELID2 | PRELI domain containing 2 | -0.0817674 |
| CADM2 | cell adhesion molecule 2 | -0.0808318 |
| PTMA | prothymosin, alpha | -0.0743418 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0742495 |
| POTEF | POTE ankyrin domain family, member F | -0.0623254 |
| RAD51B | RAD51 paralog B | -0.0574817 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0557355 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0504772 |
| LDHA | lactate dehydrogenase A | -0.0503385 |
| NEK10 | NIMA-related kinase 10 | -0.0486387 |
| SDC4 | syndecan 4 | -0.0482675 |
| TNS3 | tensin 3 | -0.0481972 |
| JUN | jun proto-oncogene | -0.0476026 |
| VCL | vinculin | -0.0463995 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0453811 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0425698 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0422185 |
| DPH6 | diphthamine biosynthesis 6 | -0.0422135 |
| RNF213 | ring finger protein 213 | -0.041002 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.040253 |
| PKM | pyruvate kinase, muscle | -0.0377384 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0366955 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0360772 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0355589 |
| HMGB2 | high mobility group box 2 | -0.0353052 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0352003 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0351443 |
| INTS6 | integrator complex subunit 6 | -0.0341434 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0340006 |
| FUS | FUS RNA binding protein | -0.0339522 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0326454 |
| CEP128 | centrosomal protein 128kDa | -0.0326072 |
| SP100 | SP100 nuclear antigen | -0.032579 |
| PCBP2 | poly(rC) binding protein 2 | -0.0321537 |
| PRKCE | protein kinase C, epsilon | -0.0313462 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0310922 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0306964 |
| ECE1 | endothelin converting enzyme 1 | -0.0304727 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0302478 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0293693 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286073 |
| DIAPH3 | diaphanous-related formin 3 | -0.0279696 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0275855 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0274842 |
| COL5A2 | collagen, type V, alpha 2 | -0.0274411 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0273032 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0272173 |
| ECT2 | epithelial cell transforming 2 | -0.0271141 |
| MCL1 | myeloid cell leukemia 1 | -0.026882 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0267812 |
| HELLS | helicase, lymphoid-specific | -0.0267168 |
| SET | SET nuclear proto-oncogene | -0.0264006 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.02617 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0259967 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0259489 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0258271 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0254391 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0254379 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0252026 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0246484 |
| HMGB1 | high mobility group box 1 | -0.0243208 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0236973 |
| FHIT | fragile histidine triad | -0.0235164 |
| YBX1 | Y box binding protein 1 | -0.0235153 |
| AEBP2 | AE binding protein 2 | -0.0228441 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0224905 |
| CALR | calreticulin | -0.0224637 |
| TMSB10 | thymosin beta 10 | -0.0221871 |
| IPO7 | importin 7 | -0.0219145 |
| FANCB | Fanconi anemia, complementation group B | -0.0218121 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0217372 |
| SVIL | supervillin | -0.0216774 |
| DNER | delta/notch-like EGF repeat containing | -0.0216577 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0212172 |
| S100A6 | S100 calcium binding protein A6 | -0.0209962 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.02091 |
| PLSCR1 | phospholipid scramblase 1 | -0.020893 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.020777 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0207526 |
| RBM39 | RNA binding motif protein 39 | -0.0205865 |
| RIGI | RNA sensor RIG-I | -0.0203319 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0201538 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0200436 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0199804 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0197622 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0197583 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0196 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0195814 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0193708 |
| SAMHD1 | SAM domain and HD domain 1 | -0.019311 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0192888 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | -0.0192609 |
