| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.206634 |
| FAM13A | family with sequence similarity 13, member A | 0.136697 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.119307 |
| CES1 | carboxylesterase 1 | 0.0995553 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0771439 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0698791 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0694106 |
| NDRG1 | N-myc downstream regulated 1 | 0.068323 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0654781 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0636658 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0632669 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0593209 |
| ARRDC3 | arrestin domain containing 3 | 0.0550567 |
| LMO7 | LIM domain 7 | 0.054523 |
| TMEM165 | transmembrane protein 165 | 0.0542472 |
| SPAG9 | sperm associated antigen 9 | 0.0523591 |
| NGLY1 | N-glycanase 1 | 0.0520383 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0487116 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0486117 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0482367 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0468609 |
| SMAD3 | SMAD family member 3 | 0.0467254 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0452642 |
| TPD52 | tumor protein D52 | 0.0443532 |
| FNIP1 | folliculin interacting protein 1 | 0.043984 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0432534 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0429944 |
| PCBP2 | poly(rC) binding protein 2 | 0.0421402 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0420703 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0409906 |
| PLEC | plectin | 0.0394937 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0394211 |
| PTEN | phosphatase and tensin homolog | 0.0374373 |
| ZNF292 | zinc finger protein 292 | 0.0372632 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0371669 |
| HELZ | helicase with zinc finger | 0.0362696 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0362387 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0357034 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0351279 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0351052 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0350838 |
| SLTM | SAFB-like, transcription modulator | 0.034996 |
| PDE8A | phosphodiesterase 8A | 0.0349705 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0345848 |
| PGK1 | phosphoglycerate kinase 1 | 0.0344451 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0341823 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0339613 |
| OGA | O-GlcNAcase | 0.0338028 |
| UVRAG | UV radiation resistance associated | 0.0335134 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0326649 |
| ZNF638 | zinc finger protein 638 | 0.032623 |
| ATOSA | atos homolog A | 0.0323728 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0320576 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0313545 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0313513 |
| SUCO | SUN domain containing ossification factor | 0.0310337 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0306271 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0305985 |
| GSK3B | glycogen synthase kinase 3 beta | 0.030469 |
| PER2 | period circadian clock 2 | 0.0303099 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0301608 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0300115 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0288977 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0287663 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0287471 |
| TXNRD1 | thioredoxin reductase 1 | 0.0281995 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0281971 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0281816 |
| YEATS2 | YEATS domain containing 2 | 0.0279936 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0272851 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0272412 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0272189 |
| SLMAP | sarcolemma associated protein | 0.0269211 |
| FRY | furry homolog (Drosophila) | 0.0268407 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0268258 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0267218 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0266922 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0265165 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0261998 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0260582 |
| WASF2 | WAS protein family, member 2 | 0.0259816 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0258645 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0258317 |
| SRP54 | signal recognition particle 54kDa | 0.0258223 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0257915 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0257399 |
| RUNX1 | runt-related transcription factor 1 | 0.0257287 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0256769 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0256395 |
| MGAT4C | MGAT4 family, member C | 0.025635 |
| MED13L | mediator complex subunit 13-like | 0.0256205 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0252609 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0250841 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0246985 |
| HYOU1 | hypoxia up-regulated 1 | 0.0246471 |
| ITSN2 | intersectin 2 | 0.0246354 |
| JMJD1C | jumonji domain containing 1C | 0.0245126 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0243758 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0242582 |
| PHF21A | PHD finger protein 21A | 0.0241618 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.150584 |
| ASPH | aspartate beta-hydroxylase | -0.12182 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.111716 |
| TMSB10 | thymosin beta 10 | -0.103524 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0796399 |
| ACTG1 | actin gamma 1 | -0.0759642 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0706968 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0690121 |
| PDLIM5 | PDZ and LIM domain 5 | -0.063181 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0600217 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0578149 |
| NABP1 | nucleic acid binding protein 1 | -0.0574273 |
| RPL35A | ribosomal protein L35a | -0.0511015 |
| RPS24 | ribosomal protein S24 | -0.0492111 |
| MYOF | myoferlin | -0.0486204 |
| INTS6 | integrator complex subunit 6 | -0.0479458 |
| VCL | vinculin | -0.0453538 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0449234 |
| RPS3 | ribosomal protein S3 | -0.043047 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0423841 |
| CCND1 | cyclin D1 | -0.0414657 |
| FTL | ferritin, light polypeptide | -0.0406201 |
| SEC61G | Sec61 gamma subunit | -0.039703 |
| RPLP1 | ribosomal protein, large, P1 | -0.038642 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0384766 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0374879 |
| RPS25 | ribosomal protein S25 | -0.0372416 |
| EGFR | epidermal growth factor receptor | -0.0369953 |
| LAMC2 | laminin, gamma 2 | -0.0366197 |
| RPL31 | ribosomal protein L31 | -0.0363581 |
| RPL37A | ribosomal protein L37a | -0.0361215 |
| IER3 | immediate early response 3 | -0.0357959 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0357063 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0347714 |
| SMYD3 | SET and MYND domain containing 3 | -0.0333303 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0333116 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0332496 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332323 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0331434 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0329585 |
| PTMA | prothymosin, alpha | -0.0328361 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0328015 |
| RPL34 | ribosomal protein L34 | -0.0327304 |
| RPS27A | ribosomal protein S27a | -0.0325511 |
| RPS8 | ribosomal protein S8 | -0.0314411 |
| AREG | amphiregulin | -0.0309746 |
| LAMA4 | laminin, alpha 4 | -0.0308418 |
| MYO1E | myosin IE | -0.0307594 |
| SP100 | SP100 nuclear antigen | -0.0302632 |
| HLA-B | major histocompatibility complex, class I, B | -0.0298461 |
| GM2A | GM2 ganglioside activator | -0.0296353 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0292204 |
| SDC1 | syndecan 1 | -0.0285178 |
| RPL19 | ribosomal protein L19 | -0.0281844 |
| SCEL | sciellin | -0.0276236 |
| RPS23 | ribosomal protein S23 | -0.0274216 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0272491 |
| S100A11 | S100 calcium binding protein A11 | -0.0269973 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0264998 |
| RPS29 | ribosomal protein S29 | -0.0261749 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0261422 |
| MT1X | metallothionein 1X | -0.0255493 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0254853 |
| CMIP | c-Maf inducing protein | -0.0253337 |
| FUS | FUS RNA binding protein | -0.025333 |
| RPLP2 | ribosomal protein, large, P2 | -0.025231 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0251599 |
| RPS21 | ribosomal protein S21 | -0.0251162 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0250415 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0249067 |
| FOXP1 | forkhead box P1 | -0.0245607 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0244675 |
| RPL11 | ribosomal protein L11 | -0.0243922 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0240614 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.0236361 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0234989 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0233236 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0231186 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0228615 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0227382 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0224059 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0221562 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0220253 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0219922 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0217999 |
| EFNA5 | ephrin-A5 | -0.0216212 |
| SLC35F3 | solute carrier family 35, member F3 | -0.02159 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0215839 |
| RPL36 | ribosomal protein L36 | -0.0215491 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0212616 |
| B2M | beta-2-microglobulin | -0.0211343 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.021014 |
| RPL23 | ribosomal protein L23 | -0.0209747 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0209607 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0209072 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0208777 |
| RPS19 | ribosomal protein S19 | -0.0208465 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0208069 |
| TNS3 | tensin 3 | -0.0206515 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0205924 |
