| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.1576 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.135656 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.134099 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.131448 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.124132 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.119135 |
| NAV2 | neuron navigator 2 | 0.110736 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0968332 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0931026 |
| VEGFA | vascular endothelial growth factor A | 0.0850905 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0802117 |
| SMAD3 | SMAD family member 3 | 0.0791957 |
| EFNA5 | ephrin-A5 | 0.0748154 |
| NDRG1 | N-myc downstream regulated 1 | 0.0730705 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0674172 |
| PCBP2 | poly(rC) binding protein 2 | 0.0665165 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0661823 |
| TMSB10 | thymosin beta 10 | 0.0653434 |
| MTSS1 | metastasis suppressor 1 | 0.0615987 |
| GOLGA4 | golgin A4 | 0.0607044 |
| FAM13A | family with sequence similarity 13, member A | 0.0600767 |
| CDH13 | cadherin 13 | 0.0599321 |
| MEF2A | myocyte enhancer factor 2A | 0.0585305 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0561417 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0551788 |
| CDCP1 | CUB domain containing protein 1 | 0.0544106 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0540023 |
| ADM | adrenomedullin | 0.0539344 |
| ZNF292 | zinc finger protein 292 | 0.0521372 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0515211 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0510777 |
| PFKP | phosphofructokinase, platelet | 0.0505996 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0478691 |
| MT2A | metallothionein 2A | 0.047137 |
| YEATS2 | YEATS domain containing 2 | 0.0459852 |
| FAM20C | family with sequence similarity 20, member C | 0.0448711 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0443375 |
| IL1B | interleukin 1, beta | 0.0442277 |
| NGLY1 | N-glycanase 1 | 0.0441562 |
| TMEM165 | transmembrane protein 165 | 0.0440222 |
| FLNB | filamin B, beta | 0.0436634 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0433528 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0424612 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0424508 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.041346 |
| MCL1 | myeloid cell leukemia 1 | 0.0406151 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0404261 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0402992 |
| RUNX1 | runt-related transcription factor 1 | 0.0399158 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0395208 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0391944 |
| ANGPTL4 | angiopoietin-like 4 | 0.0390218 |
| PRELID2 | PRELI domain containing 2 | 0.0388623 |
| PYGL | phosphorylase, glycogen, liver | 0.0385889 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0384034 |
| ZNF638 | zinc finger protein 638 | 0.0380676 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0374546 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0373864 |
| CEP250 | centrosomal protein 250kDa | 0.0370274 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0359287 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0357877 |
| EGFR | epidermal growth factor receptor | 0.0356575 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0355194 |
| RPS6 | ribosomal protein S6 | 0.0354857 |
| PTK2 | protein tyrosine kinase 2 | 0.0352726 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.035232 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0349578 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.034753 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0347362 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0342567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0339171 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0337887 |
| HLA-B | major histocompatibility complex, class I, B | 0.0333032 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0327567 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0327129 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0326043 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0323523 |
| SETD5 | SET domain containing 5 | 0.0323224 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0321689 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.032129 |
| SEPTIN9 | septin 9 | 0.0320585 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0317718 |
| OPTN | optineurin | 0.0314344 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0313213 |
| RUNX2 | runt-related transcription factor 2 | 0.0312862 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0306052 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0303445 |
| CALU | calumenin | 0.030026 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0299126 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0298601 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0291888 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.029152 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0290839 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0289024 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0281539 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0278628 |
| ADD3 | adducin 3 (gamma) | 0.027561 |
| TGM2 | transglutaminase 2 | 0.0272494 |
| FAM219A | family with sequence similarity 219, member A | 0.0272121 |
| NHSL1 | NHS-like 1 | 0.0270236 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.1657 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153926 |
| CD44 | CD44 molecule (Indian blood group) | -0.148947 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.132541 |
| GLCCI1 | glucocorticoid induced 1 | -0.100576 |
| FN1 | fibronectin 1 | -0.0993495 |
| NTN4 | netrin 4 | -0.0938129 |
| LOX | lysyl oxidase | -0.0924112 |
| NCOA7 | nuclear receptor coactivator 7 | -0.084797 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0820843 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0685761 |
| VCL | vinculin | -0.0646123 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0595597 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0581478 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0563969 |
| KYNU | kynureninase | -0.0559284 |
| VIM | vimentin | -0.0536211 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0524822 |
| ZNF804A | zinc finger protein 804A | -0.0524348 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0493376 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0491117 |
| OSMR | oncostatin M receptor | -0.0479287 |
| TNNC1 | troponin C type 1 (slow) | -0.0464991 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0457873 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0441929 |
| SYT1 | synaptotagmin I | -0.0407845 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0407225 |
| EXT1 | exostosin glycosyltransferase 1 | -0.039473 |
| DPYD | dihydropyrimidine dehydrogenase | -0.039022 |
| FTL | ferritin, light polypeptide | -0.0387775 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0370841 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0366056 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.036426 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0363867 |
| AADAC | arylacetamide deacetylase | -0.0359929 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0357642 |
| S100A6 | S100 calcium binding protein A6 | -0.0353941 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.034446 |
| IER3 | immediate early response 3 | -0.0343115 |
| SP100 | SP100 nuclear antigen | -0.0337993 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0333353 |
| RIGI | RNA sensor RIG-I | -0.0329194 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0328608 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0328545 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0328249 |
| IL1R1 | interleukin 1 receptor, type I | -0.0327262 |
| RPLP1 | ribosomal protein, large, P1 | -0.0319669 |
| RASAL2 | RAS protein activator like 2 | -0.0314033 |
| NUMB | numb homolog (Drosophila) | -0.0312677 |
| KSR1 | kinase suppressor of ras 1 | -0.0311955 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0310502 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0308576 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0307574 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0307109 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0305726 |
| FHL2 | four and a half LIM domains 2 | -0.0300504 |
| HMGA2 | high mobility group AT-hook 2 | -0.0299434 |
| MECOM | MDS1 and EVI1 complex locus | -0.029701 |
| GNAS | GNAS complex locus | -0.0292228 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0289444 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0285189 |
| FBXO11 | F-box protein 11 | -0.028133 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0278259 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0275788 |
| PALLD | palladin, cytoskeletal associated protein | -0.0270935 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0270085 |
| NF1 | neurofibromin 1 | -0.0268252 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.026531 |
| STK38L | serine/threonine kinase 38 like | -0.0257099 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0256048 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0254859 |
| RAB10 | RAB10, member RAS oncogene family | -0.0252332 |
| TMSB4X | thymosin beta 4, X-linked | -0.0252011 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0250563 |
| STK17A | serine/threonine kinase 17a | -0.0250094 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0248926 |
| EPHA4 | EPH receptor A4 | -0.0246848 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0238804 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0238167 |
| GLIS3 | GLIS family zinc finger 3 | -0.0237996 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0236372 |
| RBM39 | RNA binding motif protein 39 | -0.0236021 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0235954 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0235257 |
| ZNF644 | zinc finger protein 644 | -0.0234329 |
| MX2 | MX dynamin-like GTPase 2 | -0.0229051 |
| NLK | nemo-like kinase | -0.0227316 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0227125 |
| YBX1 | Y box binding protein 1 | -0.0225401 |
| MAP1B | microtubule-associated protein 1B | -0.0225235 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0222492 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0219524 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0218853 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0217521 |
| MYO10 | myosin X | -0.0217375 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.021713 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0214648 |
| TCF12 | transcription factor 12 | -0.0212758 |
| TKT | transketolase | -0.021201 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0211402 |
