| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.131316 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.109446 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.108642 |
| IGF2 | insulin-like growth factor 2 | 0.0964456 |
| HLA-B | major histocompatibility complex, class I, B | 0.0590512 |
| FDPS | farnesyl diphosphate synthase | 0.04516 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0442137 |
| TXNRD1 | thioredoxin reductase 1 | 0.0435759 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0419051 |
| MT1X | metallothionein 1X | 0.0403461 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0401674 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0398284 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0376503 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0375582 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0364633 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0352261 |
| FADS2 | fatty acid desaturase 2 | 0.0350252 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0344699 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0342111 |
| PLEC | plectin | 0.0339893 |
| FAM168A | family with sequence similarity 168, member A | 0.0334489 |
| RPL35A | ribosomal protein L35a | 0.0328682 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0324835 |
| LMNA | lamin A/C | 0.032273 |
| ASTN2 | astrotactin 2 | 0.0312985 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0311639 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0310193 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0307972 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0307676 |
| EGR1 | early growth response 1 | 0.0295008 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0294935 |
| HMOX1 | heme oxygenase 1 | 0.0294201 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0292077 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0289194 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0273088 |
| RPS21 | ribosomal protein S21 | 0.0266712 |
| HDAC9 | histone deacetylase 9 | 0.0263867 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0260427 |
| RNF145 | ring finger protein 145 | 0.0256463 |
| ZFHX3 | zinc finger homeobox 3 | 0.0255069 |
| WDR43 | WD repeat domain 43 | 0.0250698 |
| HLA-A | major histocompatibility complex, class I, A | 0.0247194 |
| NAV3 | neuron navigator 3 | 0.0246719 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0245501 |
| RBM25 | RNA binding motif protein 25 | 0.0245071 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0244541 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0244107 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0237696 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0236802 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0236793 |
| KIFC3 | kinesin family member C3 | 0.0231847 |
| APP | amyloid beta (A4) precursor protein | 0.023165 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0231405 |
| BRD4 | bromodomain containing 4 | 0.0230048 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0229232 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0228806 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0226144 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.022348 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0219092 |
| PTK2 | protein tyrosine kinase 2 | 0.0217693 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0217517 |
| HLA-C | major histocompatibility complex, class I, C | 0.0216138 |
| ANGPTL4 | angiopoietin-like 4 | 0.02159 |
| RNF213 | ring finger protein 213 | 0.0215603 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0214852 |
| GRAMD1B | GRAM domain containing 1B | 0.0208065 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0204319 |
| ITGB5 | integrin, beta 5 | 0.0201912 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.0199611 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | 0.0199324 |
| FLNB | filamin B, beta | 0.019919 |
| CAVIN1 | caveolae associated protein 1 | 0.0195871 |
| YME1L1 | YME1-like 1 ATPase | 0.0194052 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0193009 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0192438 |
| USP36 | ubiquitin specific peptidase 36 | 0.0191047 |
| ADAR | adenosine deaminase, RNA-specific | 0.0190842 |
| USP3 | ubiquitin specific peptidase 3 | 0.0190178 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0189032 |
| MTMR3 | myotubularin related protein 3 | 0.0188813 |
| STC1 | stanniocalcin 1 | 0.0188597 |
| MATR3 | matrin 3 | 0.0188371 |
| SQSTM1 | sequestosome 1 | 0.0187961 |
| CASC3 | cancer susceptibility candidate 3 | 0.0187422 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0186686 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0186272 |
| ACTN1 | actinin, alpha 1 | 0.0186147 |
| CYTH1 | cytohesin 1 | 0.0185738 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.018336 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0183257 |
| MUSK | muscle, skeletal, receptor tyrosine kinase | 0.0183071 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0182363 |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.0180626 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0179835 |
| B2M | beta-2-microglobulin | 0.0179431 |
| SOAT2 | sterol O-acyltransferase 2 | 0.0178094 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0177454 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | 0.017704 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0175251 |
| SMAD3 | SMAD family member 3 | 0.0175193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.282809 |
| FTL | ferritin, light polypeptide | -0.172204 |
| PM20D1 | peptidase M20 domain containing 1 | -0.154076 |
| VIM | vimentin | -0.1377 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.119873 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.116272 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.110658 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.101593 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0995563 |
| RPS27A | ribosomal protein S27a | -0.0811875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0811509 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0786052 |
| WWOX | WW domain containing oxidoreductase | -0.0761392 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0728969 |
| RPLP1 | ribosomal protein, large, P1 | -0.0707625 |
| RPS29 | ribosomal protein S29 | -0.066193 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0622808 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.05865 |
| FGB | fibrinogen beta chain | -0.0585397 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0545105 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0525629 |
| YBX1 | Y box binding protein 1 | -0.0506957 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0505713 |
| RPS12 | ribosomal protein S12 | -0.0488041 |
| RPS8 | ribosomal protein S8 | -0.0482592 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0476817 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0473993 |
| RPL31 | ribosomal protein L31 | -0.0466657 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.046089 |
| RAD51B | RAD51 paralog B | -0.0444826 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0441361 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0439209 |
| RPL37A | ribosomal protein L37a | -0.043685 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0436064 |
| RPS16 | ribosomal protein S16 | -0.0424777 |
| MYOF | myoferlin | -0.0420417 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0416554 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0410365 |
| UBC | ubiquitin C | -0.0405663 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0397034 |
| ENO1 | enolase 1, (alpha) | -0.0389856 |
| FHIT | fragile histidine triad | -0.0389731 |
| DST | dystonin | -0.0389246 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0384086 |
| LDHA | lactate dehydrogenase A | -0.0377195 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0376334 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0357521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0349438 |
| PDE10A | phosphodiesterase 10A | -0.0348546 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.034473 |
| HMGB1 | high mobility group box 1 | -0.0339366 |
| ZNF207 | zinc finger protein 207 | -0.0337938 |
| RPS2 | ribosomal protein S2 | -0.0334221 |
| RPL7 | ribosomal protein L7 | -0.0328008 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0326057 |
| RPL36 | ribosomal protein L36 | -0.0322863 |
| EFNA5 | ephrin-A5 | -0.0318431 |
| IL6 | interleukin 6 | -0.0315102 |
| TPM4 | tropomyosin 4 | -0.0312259 |
| RPS20 | ribosomal protein S20 | -0.0306012 |
| NHSL1 | NHS-like 1 | -0.0304374 |
| RPS25 | ribosomal protein S25 | -0.029943 |
| TBCA | tubulin folding cofactor A | -0.0298171 |
| S100A6 | S100 calcium binding protein A6 | -0.02977 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0287508 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0286383 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0286278 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0286261 |
| TUBA1B | tubulin, alpha 1b | -0.0285715 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0278244 |
| WAC | WW domain containing adaptor with coiled-coil | -0.027792 |
| RPL19 | ribosomal protein L19 | -0.0274809 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0274797 |
| CENPF | centromere protein F, 350/400kDa | -0.0273713 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0266645 |
| RPL30 | ribosomal protein L30 | -0.026474 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0263181 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0262738 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0257606 |
| ATXN1 | ataxin 1 | -0.0256865 |
| RPLP0 | ribosomal protein, large, P0 | -0.0255048 |
| POTEF | POTE ankyrin domain family, member F | -0.0253931 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0252039 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0248008 |
| FGG | fibrinogen gamma chain | -0.0247547 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0246142 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0245735 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0244368 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0243003 |
| PFN1 | profilin 1 | -0.0242275 |
| S100A10 | S100 calcium binding protein A10 | -0.0241758 |
| NEBL | nebulette | -0.0236142 |
| MT2A | metallothionein 2A | -0.0232757 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0232079 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0229485 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0229358 |
| RPL8 | ribosomal protein L8 | -0.0228019 |
| LDHB | lactate dehydrogenase B | -0.0227328 |
| PCBP2 | poly(rC) binding protein 2 | -0.0225812 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0224678 |
