| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | 0.128619 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0917599 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0909291 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0905098 |
| FAM13A | family with sequence similarity 13, member A | 0.08366 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0834983 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0810184 |
| PTK2 | protein tyrosine kinase 2 | 0.0797719 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.079094 |
| MATR3 | matrin 3 | 0.0767422 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0758925 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0752363 |
| PGK1 | phosphoglycerate kinase 1 | 0.0722423 |
| PTMA | prothymosin, alpha | 0.068559 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0658548 |
| TXNRD1 | thioredoxin reductase 1 | 0.0657196 |
| OGA | O-GlcNAcase | 0.0651863 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0602827 |
| FNDC3B | fibronectin type III domain containing 3B | 0.060209 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0594745 |
| RPL35A | ribosomal protein L35a | 0.0584083 |
| FTL | ferritin, light polypeptide | 0.058153 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0551053 |
| JMJD1C | jumonji domain containing 1C | 0.0540758 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0532136 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0509523 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0502355 |
| MYO10 | myosin X | 0.0495002 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0493907 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0489653 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0484534 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0484064 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0477706 |
| MYOF | myoferlin | 0.0467204 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0466541 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0423304 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0422772 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0419637 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0410906 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0407775 |
| NEK7 | NIMA-related kinase 7 | 0.0403063 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0401424 |
| FMNL2 | formin-like 2 | 0.0399606 |
| FUS | FUS RNA binding protein | 0.0399578 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0397675 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0394967 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0394035 |
| IRS2 | insulin receptor substrate 2 | 0.0390429 |
| VEGFA | vascular endothelial growth factor A | 0.0389314 |
| H1-0 | H1.0 linker histone | 0.0381775 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0381566 |
| FBXO11 | F-box protein 11 | 0.0381032 |
| CDC73 | cell division cycle 73 | 0.0378707 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0376726 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0376029 |
| ACTN4 | actinin, alpha 4 | 0.0375165 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0374932 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0373654 |
| DNER | delta/notch-like EGF repeat containing | 0.0373361 |
| RCOR1 | REST corepressor 1 | 0.0369592 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0368387 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0365651 |
| VGF | VGF nerve growth factor inducible | 0.0362879 |
| RAD51B | RAD51 paralog B | 0.0360121 |
| DTNA | dystrobrevin, alpha | 0.0358941 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0358448 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0356667 |
| GPC6 | glypican 6 | 0.0353977 |
| S100P | S100 calcium binding protein P | 0.03532 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0353034 |
| PER1 | period circadian clock 1 | 0.0348849 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0346122 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0344724 |
| FOXP1 | forkhead box P1 | 0.0343055 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0342836 |
| YTHDC1 | YTH domain containing 1 | 0.0342449 |
| VMP1 | vacuole membrane protein 1 | 0.0341926 |
| RSF1 | remodeling and spacing factor 1 | 0.0341854 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0339661 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0339015 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0333555 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | 0.0333455 |
| TAC4 | tachykinin 4 (hemokinin) | 0.0332379 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0329928 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0328651 |
| TUT7 | terminal uridylyl transferase 7 | 0.0326568 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0324968 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0324645 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0324444 |
| STEAP4 | STEAP family member 4 | 0.032311 |
| SSH1 | slingshot protein phosphatase 1 | 0.032112 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0320004 |
| XPO1 | exportin 1 | 0.0319106 |
| CTBP2 | C-terminal binding protein 2 | 0.0318024 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.031798 |
| RPL8 | ribosomal protein L8 | 0.0317867 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0317082 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0316201 |
| ADAR | adenosine deaminase, RNA-specific | 0.0314813 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0314524 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.106066 |
| FN1 | fibronectin 1 | -0.102332 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.102255 |
| ANXA2 | annexin A2 | -0.0876607 |
| KRT17 | keratin 17, type I | -0.0869025 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0779142 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0763321 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.074026 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0707525 |
| DSG2 | desmoglein 2 | -0.0658301 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0638916 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0636247 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0624265 |
| GOLGB1 | golgin B1 | -0.0614841 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0613048 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0586775 |
| TMEM165 | transmembrane protein 165 | -0.0567531 |
| MYO1E | myosin IE | -0.0562341 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0560844 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0554709 |
| MUC16 | mucin 16, cell surface associated | -0.0548555 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0538385 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0531116 |
| IGF2 | insulin-like growth factor 2 | -0.0514267 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0499964 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0483333 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0474799 |
| ACTG1 | actin gamma 1 | -0.0466586 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0464516 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0461342 |
| KIAA1217 | KIAA1217 | -0.045872 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0453788 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0451554 |
| CDH13 | cadherin 13 | -0.0447176 |
| ATOSA | atos homolog A | -0.0443738 |
| SLTM | SAFB-like, transcription modulator | -0.0438155 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0436145 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.043036 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0427085 |
| FOXO1 | forkhead box O1 | -0.0426665 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0426089 |
| POTEF | POTE ankyrin domain family, member F | -0.0407981 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0404758 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0399441 |
| INHBA | inhibin, beta A | -0.0397349 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0392915 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0389076 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.038809 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0382751 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0377174 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0371269 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0370645 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0369461 |
| RPS25 | ribosomal protein S25 | -0.0368238 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0365565 |
| ZNF217 | zinc finger protein 217 | -0.0364492 |
| MYO9A | myosin IXA | -0.0363791 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0362726 |
| CCDC91 | coiled-coil domain containing 91 | -0.0358624 |
| SH3D19 | SH3 domain containing 19 | -0.0356636 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0356421 |
| CPE | carboxypeptidase E | -0.035639 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0354004 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0350171 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0348752 |
| FNIP1 | folliculin interacting protein 1 | -0.034324 |
| PRSS23 | protease, serine, 23 | -0.0343166 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0342959 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0340817 |
| STC1 | stanniocalcin 1 | -0.0340312 |
| GPATCH2L | G patch domain containing 2-like | -0.0339149 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0338978 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0338435 |
| SEC24D | SEC24 family member D | -0.0336359 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.033486 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0334544 |
| SLMAP | sarcolemma associated protein | -0.0332344 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0330644 |
| MAP7 | microtubule-associated protein 7 | -0.0328763 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0327406 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0325226 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0324687 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0323447 |
| PLS3 | plastin 3 | -0.0318394 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0317059 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0315369 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0313591 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0306175 |
| DENND4A | DENN/MADD domain containing 4A | -0.0303335 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0300876 |
| CAB39 | calcium binding protein 39 | -0.0300015 |
| NEBL | nebulette | -0.0299213 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0296712 |
| ZNF704 | zinc finger protein 704 | -0.0296634 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0292137 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0290856 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0290526 |
| SCEL | sciellin | -0.0287223 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0286538 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0286268 |
