| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRAMD1B | GRAM domain containing 1B | 0.139491 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.110126 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.109209 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.100714 |
| TMSB10 | thymosin beta 10 | 0.0961889 |
| PLEC | plectin | 0.0910081 |
| KRT18 | keratin 18, type I | 0.0774247 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0772472 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0734914 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0665953 |
| OGA | O-GlcNAcase | 0.0655367 |
| TPM3 | tropomyosin 3 | 0.0634144 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0619062 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0617648 |
| RPS21 | ribosomal protein S21 | 0.0597858 |
| PGK1 | phosphoglycerate kinase 1 | 0.0580094 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0560394 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0559499 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0559427 |
| RPL35A | ribosomal protein L35a | 0.0551559 |
| CTTN | cortactin | 0.0545749 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0514823 |
| ADAR | adenosine deaminase, RNA-specific | 0.0499911 |
| RTN4 | reticulon 4 | 0.0488931 |
| RPS19 | ribosomal protein S19 | 0.0473293 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0470171 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0469742 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0465855 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0465804 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0464826 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0452143 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0437216 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0430319 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0428985 |
| TXNRD1 | thioredoxin reductase 1 | 0.0424509 |
| SMAD3 | SMAD family member 3 | 0.0424318 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0423461 |
| RPL23 | ribosomal protein L23 | 0.0418249 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0417733 |
| ATP11A | ATPase, class VI, type 11A | 0.0415072 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.0405284 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0402092 |
| DIDO1 | death inducer-obliterator 1 | 0.0394173 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0390851 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0390789 |
| CEP250 | centrosomal protein 250kDa | 0.0388041 |
| FUS | FUS RNA binding protein | 0.0387012 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0380091 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0372527 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.037095 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0370515 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0369543 |
| KRT8 | keratin 8, type II | 0.0364727 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0362797 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0362181 |
| RBM33 | RNA binding motif protein 33 | 0.0356347 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.035494 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0348305 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0347165 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0346582 |
| RRM2 | ribonucleotide reductase M2 | 0.034216 |
| HLA-B | major histocompatibility complex, class I, B | 0.0339992 |
| RPL26 | ribosomal protein L26 | 0.0338147 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0336436 |
| AHNAK | AHNAK nucleoprotein | 0.0336335 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0335463 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0329171 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.0322859 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0322039 |
| MCL1 | myeloid cell leukemia 1 | 0.0319003 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0313713 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0312266 |
| RASAL2 | RAS protein activator like 2 | 0.0308243 |
| RPL4 | ribosomal protein L4 | 0.030647 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0306227 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | 0.0303268 |
| BRD2 | bromodomain containing 2 | 0.0299362 |
| FMNL2 | formin-like 2 | 0.0299045 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0298079 |
| RPL11 | ribosomal protein L11 | 0.0295291 |
| RPS4X | ribosomal protein S4, X-linked | 0.0293889 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0292252 |
| YBX3 | Y box binding protein 3 | 0.0291457 |
| CEP192 | centrosomal protein 192kDa | 0.0291292 |
| ACTN1 | actinin, alpha 1 | 0.0290737 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.0289835 |
| WDR43 | WD repeat domain 43 | 0.0288626 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287678 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0285811 |
| RPS10 | ribosomal protein S10 | 0.0283148 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0282658 |
| VCP | valosin containing protein | 0.0282653 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0281596 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0279757 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0277197 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0277183 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0275288 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.027367 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0273487 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0272662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.215306 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.110131 |
| VIM | vimentin | -0.108368 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0939156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0857283 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0671053 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0618905 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0532889 |
| CANX | calnexin | -0.0517559 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0515872 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0479267 |
| POTEF | POTE ankyrin domain family, member F | -0.0475205 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0463462 |
| PDE10A | phosphodiesterase 10A | -0.0433607 |
| MORF4L2 | mortality factor 4 like 2 | -0.0425974 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0396763 |
| EGR1 | early growth response 1 | -0.0385401 |
| PYGL | phosphorylase, glycogen, liver | -0.0365734 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0362842 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0341841 |
| TPM4 | tropomyosin 4 | -0.0341642 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0341172 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0340579 |
| ZNF207 | zinc finger protein 207 | -0.0339289 |
| GOLGB1 | golgin B1 | -0.0338582 |
| ENO1 | enolase 1, (alpha) | -0.0335323 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0331212 |
| TLN1 | talin 1 | -0.0322686 |
| SRP72 | signal recognition particle 72kDa | -0.0316716 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0314458 |
| LDHA | lactate dehydrogenase A | -0.0312176 |
| GNAS | GNAS complex locus | -0.0299178 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0299073 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0297848 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0296594 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0296111 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0295127 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0284626 |
| VCL | vinculin | -0.0282482 |
| NLGN1 | neuroligin 1 | -0.0282035 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0281435 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0279365 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0278188 |
| BPTF | bromodomain PHD finger transcription factor | -0.0277227 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0274088 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0272193 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0268591 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0263777 |
| COPA | coatomer protein complex, subunit alpha | -0.0259252 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0259135 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0257745 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0257198 |
| NF1 | neurofibromin 1 | -0.0256392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.02524 |
| NCOA7 | nuclear receptor coactivator 7 | -0.02521 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0245387 |
| NBEAL1 | neurobeachin-like 1 | -0.0241912 |
| INTS6 | integrator complex subunit 6 | -0.0240966 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0239965 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0235884 |
| TUBA1B | tubulin, alpha 1b | -0.0232177 |
| DCAF10 | DDB1 and CUL4 associated factor 10 | -0.023213 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0227808 |
| PRELID2 | PRELI domain containing 2 | -0.0225475 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0225109 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0224967 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0223366 |
| TUBB | tubulin, beta class I | -0.0223314 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0219649 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0219184 |
| AEBP2 | AE binding protein 2 | -0.0217231 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0215708 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0213731 |
| SEC24A | SEC24 family member A | -0.0213285 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.0213125 |
| SRP54 | signal recognition particle 54kDa | -0.0210624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0210119 |
| GOLGA4 | golgin A4 | -0.0208044 |
| FMN1 | formin 1 | -0.0200921 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0199125 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0197442 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.0197403 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0195366 |
| CD2AP | CD2-associated protein | -0.019243 |
| MYADM | myeloid-associated differentiation marker | -0.0192136 |
| HOMER1 | homer scaffolding protein 1 | -0.0191953 |
| BBX | bobby sox homolog (Drosophila) | -0.0191302 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0190532 |
| STC1 | stanniocalcin 1 | -0.0190363 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0190185 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0189401 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0188632 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0188583 |
| MMP12 | matrix metallopeptidase 12 | -0.0188489 |
| TRIM9 | tripartite motif containing 9 | -0.0187797 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0184835 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.0184103 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0181063 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0180669 |
| ZNF644 | zinc finger protein 644 | -0.017985 |
