| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MCL1 | myeloid cell leukemia 1 | 0.116253 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0946295 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0815834 |
| GRAMD1B | GRAM domain containing 1B | 0.0804392 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0713157 |
| GDA | guanine deaminase | 0.0701135 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.064128 |
| HLA-A | major histocompatibility complex, class I, A | 0.0623742 |
| PCBP2 | poly(rC) binding protein 2 | 0.0613098 |
| FLNB | filamin B, beta | 0.0601078 |
| FN1 | fibronectin 1 | 0.0578755 |
| MSN | moesin | 0.0551826 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0548156 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0533984 |
| FMNL2 | formin-like 2 | 0.0509317 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0509264 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0482486 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0482077 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.047112 |
| TBXT | T-box transcription factor T | 0.0466646 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0465752 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0461729 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0456588 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0451371 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0451213 |
| AUTS2 | autism susceptibility candidate 2 | 0.0435651 |
| EZR | ezrin | 0.0428374 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0426921 |
| RPS6 | ribosomal protein S6 | 0.0424744 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0421448 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0412074 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0401466 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0392819 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0388688 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0361784 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0359631 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0357364 |
| B2M | beta-2-microglobulin | 0.0355855 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.034823 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0346022 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0341333 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0337442 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0337331 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0331159 |
| LAMA5 | laminin, alpha 5 | 0.0326076 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0323423 |
| VMP1 | vacuole membrane protein 1 | 0.0322702 |
| VIM | vimentin | 0.032225 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0317327 |
| MT2A | metallothionein 2A | 0.0316265 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0315938 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0313711 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0308201 |
| TXNIP | thioredoxin interacting protein | 0.0307485 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0301796 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0300622 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0298024 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0296872 |
| DNER | delta/notch-like EGF repeat containing | 0.0290793 |
| RPS12 | ribosomal protein S12 | 0.0289281 |
| CD109 | CD109 molecule | 0.0288921 |
| TPM3 | tropomyosin 3 | 0.0288427 |
| RNF145 | ring finger protein 145 | 0.0285295 |
| CTSL | cathepsin L | 0.028394 |
| PRRC2C | proline-rich coiled-coil 2C | 0.028362 |
| PGK1 | phosphoglycerate kinase 1 | 0.0281866 |
| RPS23 | ribosomal protein S23 | 0.0280136 |
| RPL3 | ribosomal protein L3 | 0.0279905 |
| CTBP2 | C-terminal binding protein 2 | 0.0273508 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0269143 |
| NIPA1 | non imprinted in Prader-Willi/Angelman syndrome 1 | 0.0267294 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266244 |
| RPL21 | ribosomal protein L21 | 0.0263406 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0262461 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0254934 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250691 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0249977 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0247573 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0243093 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0238418 |
| ASTN2 | astrotactin 2 | 0.0237527 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0236538 |
| FAM13A | family with sequence similarity 13, member A | 0.023511 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0234037 |
| HLA-B | major histocompatibility complex, class I, B | 0.023298 |
| POTEF | POTE ankyrin domain family, member F | 0.0232466 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0231256 |
| RPS13 | ribosomal protein S13 | 0.0229872 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0229189 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0228607 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0228358 |
| HDAC4 | histone deacetylase 4 | 0.0228257 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0228135 |
| MEF2D | myocyte enhancer factor 2D | 0.0226237 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0225314 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0225211 |
| DHFR | dihydrofolate reductase | 0.0222384 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0221453 |
| STC1 | stanniocalcin 1 | 0.0221271 |
| PLEC | plectin | 0.0220942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.250569 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.200335 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.180047 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.112149 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0809062 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0796337 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0702534 |
| ASPH | aspartate beta-hydroxylase | -0.0615714 |
| GNAS | GNAS complex locus | -0.0591035 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0587207 |
| RPS24 | ribosomal protein S24 | -0.0584722 |
| PDE10A | phosphodiesterase 10A | -0.057001 |
| VCL | vinculin | -0.0543891 |
| NRCAM | neuronal cell adhesion molecule | -0.0543167 |
| CANX | calnexin | -0.0534553 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.051441 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0504832 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0503712 |
| SMYD3 | SET and MYND domain containing 3 | -0.0489275 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0438841 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.043854 |
| COL5A2 | collagen, type V, alpha 2 | -0.0435737 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0434524 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0423461 |
| MYOF | myoferlin | -0.0417698 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0417184 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0417172 |
| MORF4L2 | mortality factor 4 like 2 | -0.039537 |
| ARF1 | ADP-ribosylation factor 1 | -0.0393292 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0393067 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0381036 |
| PCBP3 | poly(rC) binding protein 3 | -0.037486 |
| ENO1 | enolase 1, (alpha) | -0.0363473 |
| TXNRD1 | thioredoxin reductase 1 | -0.0358315 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0351625 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0349035 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0343687 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.034071 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0339626 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0331925 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0328185 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0325875 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0323927 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.032386 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0319161 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0315358 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0313285 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0310128 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300577 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0293378 |
| LSAMP | limbic system-associated membrane protein | -0.0291777 |
| TNPO1 | transportin 1 | -0.0290283 |
| LDHA | lactate dehydrogenase A | -0.0289473 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.0284962 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0281811 |
| RPL38 | ribosomal protein L38 | -0.0279784 |
| CTSC | cathepsin C | -0.027885 |
| PRKD3 | protein kinase D3 | -0.0278216 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0275894 |
| RHOB | ras homolog family member B | -0.026986 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0266777 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.025893 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258734 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0246946 |
| HDLBP | high density lipoprotein binding protein | -0.0242825 |
| EPHA4 | EPH receptor A4 | -0.0240193 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0238908 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0237886 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0235509 |
| CUL4B | cullin 4B | -0.0235281 |
| SRGN | serglycin | -0.0234946 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0228907 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0226532 |
| RPL6 | ribosomal protein L6 | -0.0224566 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0224359 |
| IER3 | immediate early response 3 | -0.0222002 |
| RRBP1 | ribosome binding protein 1 | -0.0220041 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0216113 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0214608 |
| RPS27A | ribosomal protein S27a | -0.0213586 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0213135 |
| CADM2 | cell adhesion molecule 2 | -0.021146 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0210577 |
| SPAG9 | sperm associated antigen 9 | -0.0208332 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0203256 |
| HMGB1 | high mobility group box 1 | -0.0202076 |
| PM20D1 | peptidase M20 domain containing 1 | -0.020112 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0201074 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0199994 |
| RGS2 | regulator of G-protein signaling 2 | -0.0199396 |
| MKI67 | marker of proliferation Ki-67 | -0.0194527 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0191559 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.0191379 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0190139 |
| RBM39 | RNA binding motif protein 39 | -0.0189147 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0188447 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0188331 |
| ZNF804A | zinc finger protein 804A | -0.0186809 |
| RPLP0 | ribosomal protein, large, P0 | -0.0186009 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0186 |
