| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berbamine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | 0.0892033 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0717812 |
| DST | dystonin | 0.070479 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0704209 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0687313 |
| MYO10 | myosin X | 0.0650876 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0570306 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0555216 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0547016 |
| WDR43 | WD repeat domain 43 | 0.0515465 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0508719 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0507774 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.050461 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0496479 |
| ZNF217 | zinc finger protein 217 | 0.0491809 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0478262 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0476962 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0462011 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0458169 |
| NTM | neurotrimin | 0.0455717 |
| RBM33 | RNA binding motif protein 33 | 0.0448374 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.043886 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.043487 |
| FAM168A | family with sequence similarity 168, member A | 0.0415099 |
| USP3 | ubiquitin specific peptidase 3 | 0.0410106 |
| ENAH | enabled homolog (Drosophila) | 0.0403498 |
| RHEB | Ras homolog enriched in brain | 0.0401925 |
| SYT1 | synaptotagmin I | 0.0399656 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0398179 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0397654 |
| MB21D2 | Mab-21 domain containing 2 | 0.0396581 |
| QKI | QKI, KH domain containing, RNA binding | 0.0393633 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0389938 |
| PTK2 | protein tyrosine kinase 2 | 0.0383863 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.037849 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0372184 |
| CCN2 | cellular communication network factor 2 | 0.0371513 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0369682 |
| NCKAP1 | NCK-associated protein 1 | 0.0368863 |
| PDGFC | platelet derived growth factor C | 0.0367232 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0366835 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035182 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0349686 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0346385 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0345709 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0344897 |
| MED13L | mediator complex subunit 13-like | 0.0343779 |
| CDC73 | cell division cycle 73 | 0.0338995 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0335787 |
| APP | amyloid beta (A4) precursor protein | 0.033099 |
| PDS5B | PDS5 cohesin associated factor B | 0.0315119 |
| ZNF608 | zinc finger protein 608 | 0.0314771 |
| EMP1 | epithelial membrane protein 1 | 0.0313413 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0312369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0311636 |
| FBXO11 | F-box protein 11 | 0.0309898 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0309314 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0306008 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0305555 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0303825 |
| MTF2 | metal response element binding transcription factor 2 | 0.0302583 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0299189 |
| YAP1 | Yes-associated protein 1 | 0.0297819 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0296673 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0294412 |
| TPM3 | tropomyosin 3 | 0.029301 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0287521 |
| HBS1L | HBS1-like translational GTPase | 0.0287031 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0285562 |
| VMP1 | vacuole membrane protein 1 | 0.0280363 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.027977 |
| NBAS | neuroblastoma amplified sequence | 0.0274464 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 | 0.0273491 |
| NUP58 | nucleoporin 58 | 0.0270633 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0265666 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0265208 |
| PGK1 | phosphoglycerate kinase 1 | 0.0262966 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0262493 |
| CPNE8 | copine VIII | 0.0262403 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0260712 |
| NCOR2 | nuclear receptor corepressor 2 | 0.025832 |
| MEMO1 | mediator of cell motility 1 | 0.0257921 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0256882 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0256725 |
| KIF1B | kinesin family member 1B | 0.0254779 |
| RIOK3 | RIO kinase 3 | 0.0253953 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0253282 |
| GASK1B | golgi associated kinase 1B | 0.0252923 |
| ANXA5 | annexin A5 | 0.0252142 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0251672 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0250052 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0249326 |
| SACS | sacsin molecular chaperone | 0.0248698 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0248541 |
| AFAP1 | actin filament associated protein 1 | 0.0247603 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0246352 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0246141 |
| TCERG1 | transcription elongation regulator 1 | 0.0245575 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0244692 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0243578 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.180779 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.113052 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.109547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0879188 |
| TMSB10 | thymosin beta 10 | -0.0838029 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0784923 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0760849 |
| PCDH9 | protocadherin 9 | -0.0733743 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0637113 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0620375 |
| RPS8 | ribosomal protein S8 | -0.059105 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0549775 |
| GNAS | GNAS complex locus | -0.0545332 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0496442 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0492173 |
| PTMA | prothymosin, alpha | -0.0474529 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0470691 |
| RPLP1 | ribosomal protein, large, P1 | -0.0458217 |
| COL1A2 | collagen, type I, alpha 2 | -0.0442456 |
| CADM2 | cell adhesion molecule 2 | -0.0441626 |
| SNX6 | sorting nexin 6 | -0.0433862 |
| RPL35A | ribosomal protein L35a | -0.0431349 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0409771 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0398627 |
| ACTG1 | actin gamma 1 | -0.0394391 |
| RPS16 | ribosomal protein S16 | -0.0387746 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0384031 |
| PEG10 | paternally expressed 10 | -0.0383518 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0382765 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0372976 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0361689 |
| CAVIN1 | caveolae associated protein 1 | -0.0358894 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0358437 |
| MEIS2 | Meis homeobox 2 | -0.0353432 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0352869 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0349874 |
| RPL31 | ribosomal protein L31 | -0.0344779 |
| COL3A1 | collagen, type III, alpha 1 | -0.0340104 |
| MKI67 | marker of proliferation Ki-67 | -0.0332064 |
| MAP4 | microtubule-associated protein 4 | -0.0323581 |
| B2M | beta-2-microglobulin | -0.0320483 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0310449 |
| RPS6 | ribosomal protein S6 | -0.0309485 |
| RPS24 | ribosomal protein S24 | -0.030316 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0302696 |
| RFPL4B | ret finger protein-like 4B | -0.030235 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0295128 |
| HMGB1 | high mobility group box 1 | -0.0291334 |
| RPS27 | ribosomal protein S27 | -0.0289815 |
| RPL38 | ribosomal protein L38 | -0.028946 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0284204 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0283774 |
| HMGB2 | high mobility group box 2 | -0.0282644 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0282044 |
| NRG1 | neuregulin 1 | -0.0280303 |
| SERF2 | small EDRK-rich factor 2 | -0.0279376 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0279367 |
| RPL9 | ribosomal protein L9 | -0.0276317 |
| APOE | apolipoprotein E | -0.0275101 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0274479 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0274313 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0272432 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0272341 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0271015 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270405 |
| FTL | ferritin, light polypeptide | -0.0269894 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263916 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0263289 |
| SMC5 | structural maintenance of chromosomes 5 | -0.0260918 |
| MTDH | metadherin | -0.0260098 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0256302 |
| THOC2 | THO complex 2 | -0.025456 |
| RDX | radixin | -0.0254426 |
| RPS19 | ribosomal protein S19 | -0.025178 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0251215 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0250595 |
| LDHA | lactate dehydrogenase A | -0.0249017 |
| INTS6 | integrator complex subunit 6 | -0.0248195 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0240352 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0239921 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0239551 |
| FBXO27 | F-box protein 27 | -0.0239298 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.023887 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0238229 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0238215 |
| GPC3 | glypican 3 | -0.0237715 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0235028 |
| CCDC34 | coiled-coil domain containing 34 | -0.0234419 |
| RPS21 | ribosomal protein S21 | -0.023441 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0233866 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0232533 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0231453 |
| PARK7 | parkinson protein 7 | -0.0231226 |
| TEX11 | testis expressed 11 | -0.0230113 |
| ANLN | anillin, actin binding protein | -0.0227679 |
| FOXP2 | forkhead box P2 | -0.0225667 |
| TPR | translocated promoter region, nuclear basket protein | -0.0224863 |
| NDRG1 | N-myc downstream regulated 1 | -0.0223617 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0221862 |
| TXNRD1 | thioredoxin reductase 1 | -0.0221834 |
