| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | 0.115476 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.112737 |
| ADM | adrenomedullin | 0.110209 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.096619 |
| FN1 | fibronectin 1 | 0.0712618 |
| NDRG1 | N-myc downstream regulated 1 | 0.0710423 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0618588 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.060285 |
| MT2A | metallothionein 2A | 0.0602436 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0586124 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0576766 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0546535 |
| PGK1 | phosphoglycerate kinase 1 | 0.0545574 |
| ATP13A3 | ATPase type 13A3 | 0.0544768 |
| OGA | O-GlcNAcase | 0.0541228 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0532599 |
| MT1X | metallothionein 1X | 0.0513529 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0501096 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0494928 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0484229 |
| SFTPA2 | surfactant protein A2 | 0.0474508 |
| VEGFA | vascular endothelial growth factor A | 0.0461981 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0454862 |
| RBM39 | RNA binding motif protein 39 | 0.0409894 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0401915 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0391099 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0381935 |
| RPL35A | ribosomal protein L35a | 0.0380989 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0350004 |
| HLA-A | major histocompatibility complex, class I, A | 0.0343562 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0341085 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0338116 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0337762 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0337713 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0318879 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0317448 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0298698 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0296683 |
| GLIS3 | GLIS family zinc finger 3 | 0.0293794 |
| CCNL1 | cyclin L1 | 0.0293278 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0292192 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.027412 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0273969 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0268305 |
| PHIP | pleckstrin homology domain interacting protein | 0.0260577 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0246343 |
| SDC4 | syndecan 4 | 0.0242138 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0240505 |
| RBM6 | RNA binding motif protein 6 | 0.0239219 |
| DENND5A | DENN/MADD domain containing 5A | 0.0239021 |
| AFDN | afadin, adherens junction formation factor | 0.0237484 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0230485 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0228073 |
| SBF2 | SET binding factor 2 | 0.0227323 |
| FUS | FUS RNA binding protein | 0.0226501 |
| VMP1 | vacuole membrane protein 1 | 0.0225391 |
| RPS21 | ribosomal protein S21 | 0.0225244 |
| SMAD3 | SMAD family member 3 | 0.0220813 |
| INSIG1 | insulin induced gene 1 | 0.0219866 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0219561 |
| MSN | moesin | 0.0217866 |
| HLA-C | major histocompatibility complex, class I, C | 0.0216766 |
| FAM20C | family with sequence similarity 20, member C | 0.0213492 |
| CEP95 | centrosomal protein 95kDa | 0.0210421 |
| TMSB10 | thymosin beta 10 | 0.0207769 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0207647 |
| TMEM41B | transmembrane protein 41B | 0.0204701 |
| CEP250 | centrosomal protein 250kDa | 0.0202066 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0200092 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0199462 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0196952 |
| TOP1 | topoisomerase (DNA) I | 0.0196377 |
| BRD2 | bromodomain containing 2 | 0.0195806 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0194631 |
| SF1 | splicing factor 1 | 0.0194105 |
| INHBA | inhibin, beta A | 0.0194071 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.019337 |
| YEATS2 | YEATS domain containing 2 | 0.0192906 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0192252 |
| RPL11 | ribosomal protein L11 | 0.0191704 |
| RNF213 | ring finger protein 213 | 0.0189941 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0189898 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0189636 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0188429 |
| YTHDC1 | YTH domain containing 1 | 0.0187058 |
| SMAP1 | small ArfGAP 1 | 0.01869 |
| RASA2 | RAS p21 protein activator 2 | 0.0185263 |
| ZNF292 | zinc finger protein 292 | 0.0184779 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.018332 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0182015 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0181576 |
| RBMX | RNA binding motif protein, X-linked | 0.0178955 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | 0.0178769 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0178701 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0176632 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0174071 |
| RNF145 | ring finger protein 145 | 0.0173877 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0173196 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0172278 |
| RLF | rearranged L-myc fusion | 0.0171454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.282105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149553 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.114684 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.112868 |
| LDHA | lactate dehydrogenase A | -0.105402 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.105277 |
| VCL | vinculin | -0.10109 |
| ENO1 | enolase 1, (alpha) | -0.0992925 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0839225 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0816645 |
| FRMD4A | FERM domain containing 4A | -0.0801337 |
| PLIN2 | perilipin 2 | -0.0722618 |
| HDAC9 | histone deacetylase 9 | -0.0713352 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.070884 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0701865 |
| ANXA2 | annexin A2 | -0.0642788 |
| CD44 | CD44 molecule (Indian blood group) | -0.0603242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0597602 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0574213 |
| UBC | ubiquitin C | -0.0569684 |
| SQSTM1 | sequestosome 1 | -0.0562455 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0561699 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0549103 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0546635 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0531693 |
| TPM1 | tropomyosin 1 (alpha) | -0.0519383 |
| MYOF | myoferlin | -0.0518757 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0515182 |
| ASPH | aspartate beta-hydroxylase | -0.0512391 |
| PKM | pyruvate kinase, muscle | -0.049725 |
| DST | dystonin | -0.0496807 |
| RPS27A | ribosomal protein S27a | -0.0489191 |
| CANX | calnexin | -0.0488663 |
| VCAN | versican | -0.0475457 |
| RPS12 | ribosomal protein S12 | -0.0470205 |
| PALLD | palladin, cytoskeletal associated protein | -0.0423068 |
| INTS6 | integrator complex subunit 6 | -0.0411871 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0410104 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0403922 |
| GPC6 | glypican 6 | -0.0400663 |
| RPLP1 | ribosomal protein, large, P1 | -0.039603 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0380188 |
| AHNAK | AHNAK nucleoprotein | -0.035872 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0356722 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.035659 |
| FTL | ferritin, light polypeptide | -0.0345195 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0338518 |
| MORF4L2 | mortality factor 4 like 2 | -0.0333207 |
| EGFR | epidermal growth factor receptor | -0.0331419 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0330604 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0329417 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0323881 |
| VDAC1 | voltage-dependent anion channel 1 | -0.031991 |
| HMGA2 | high mobility group AT-hook 2 | -0.0317657 |
| IER3 | immediate early response 3 | -0.0312847 |
| THBS1 | thrombospondin 1 | -0.0311875 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310154 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0309082 |
| DIAPH2 | diaphanous-related formin 2 | -0.030585 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.030252 |
| WWOX | WW domain containing oxidoreductase | -0.0300442 |
| RIGI | RNA sensor RIG-I | -0.0298104 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0294977 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0294882 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.029188 |
| RPS6 | ribosomal protein S6 | -0.0288922 |
| GOLGB1 | golgin B1 | -0.0288791 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.027935 |
| TENM2 | teneurin transmembrane protein 2 | -0.0279131 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0277909 |
| NAV1 | neuron navigator 1 | -0.0276332 |
| SEPTIN9 | septin 9 | -0.0268046 |
| CTSD | cathepsin D | -0.0267733 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0267274 |
| PTMA | prothymosin, alpha | -0.0267019 |
| TPM4 | tropomyosin 4 | -0.026307 |
| CDH13 | cadherin 13 | -0.0261204 |
| CALR | calreticulin | -0.0259889 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0251251 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0247129 |
| YBX1 | Y box binding protein 1 | -0.0246794 |
| PHF3 | PHD finger protein 3 | -0.0240542 |
| HLA-E | major histocompatibility complex, class I, E | -0.0239346 |
| PDE10A | phosphodiesterase 10A | -0.0238429 |
| HMGB1 | high mobility group box 1 | -0.0238369 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0237153 |
| EFNA5 | ephrin-A5 | -0.0236712 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0234981 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0233675 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0227235 |
| RUNX1 | runt-related transcription factor 1 | -0.022517 |
| BBX | bobby sox homolog (Drosophila) | -0.0224374 |
| RPS2 | ribosomal protein S2 | -0.022425 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0220802 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0220058 |
| ARFGEF3 | ARFGEF family member 3 | -0.0217721 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0216852 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0216063 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0214166 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0211715 |