| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berbamine perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berbamine_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.207274 |
| NDRG1 | N-myc downstream regulated 1 | 0.134174 |
| MT2A | metallothionein 2A | 0.119179 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0899355 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0836819 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0782029 |
| NRXN3 | neurexin 3 | 0.0754686 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0674009 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0664848 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0606948 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0580797 |
| MT1X | metallothionein 1X | 0.0569117 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0567197 |
| FNIP1 | folliculin interacting protein 1 | 0.0515077 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.051168 |
| VEGFA | vascular endothelial growth factor A | 0.0508398 |
| IL6 | interleukin 6 | 0.0478509 |
| GOLGA4 | golgin A4 | 0.04648 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0461162 |
| FAM13A | family with sequence similarity 13, member A | 0.0455794 |
| ARRDC3 | arrestin domain containing 3 | 0.0443883 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0421039 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0417202 |
| RNF145 | ring finger protein 145 | 0.0404523 |
| PRELID2 | PRELI domain containing 2 | 0.0398043 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0393371 |
| VEGFC | vascular endothelial growth factor C | 0.0380962 |
| EFNA5 | ephrin-A5 | 0.0374606 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0370058 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.03671 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0365267 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0363229 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0355568 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0355256 |
| ATP13A3 | ATPase type 13A3 | 0.0345052 |
| TMEM165 | transmembrane protein 165 | 0.033951 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0337435 |
| ANKRD11 | ankyrin repeat domain 11 | 0.033284 |
| TMF1 | TATA element modulatory factor 1 | 0.0329479 |
| NF1 | neurofibromin 1 | 0.0327533 |
| TGFB1 | transforming growth factor, beta 1 | 0.0327252 |
| ZNF638 | zinc finger protein 638 | 0.0325494 |
| SEPTIN9 | septin 9 | 0.0323385 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.032161 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0320136 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0317486 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0314718 |
| CADM1 | cell adhesion molecule 1 | 0.0314506 |
| COG6 | component of oligomeric golgi complex 6 | 0.0310064 |
| GOLGB1 | golgin B1 | 0.0307694 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0306552 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0303337 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0302523 |
| RUNX1 | runt-related transcription factor 1 | 0.0299414 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0296993 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.029684 |
| YBX1 | Y box binding protein 1 | 0.0292462 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0290214 |
| RPL35A | ribosomal protein L35a | 0.0289152 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0288631 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0288555 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0288466 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0283922 |
| EGFR | epidermal growth factor receptor | 0.0283257 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0281205 |
| SNX13 | sorting nexin 13 | 0.0279539 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0277308 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0276142 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0276001 |
| RASAL2 | RAS protein activator like 2 | 0.0274434 |
| ADM | adrenomedullin | 0.027074 |
| COG5 | component of oligomeric golgi complex 5 | 0.0265782 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0265674 |
| RPL23 | ribosomal protein L23 | 0.0265669 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0264573 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0264197 |
| FAM13B | family with sequence similarity 13, member B | 0.0263624 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0253238 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0252872 |
| SETD5 | SET domain containing 5 | 0.0252088 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0249794 |
| CA9 | carbonic anhydrase IX | 0.024852 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0246837 |
| OPTN | optineurin | 0.0246475 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0246147 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0241753 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0241518 |
| AHR | aryl hydrocarbon receptor | 0.0239939 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0238893 |
| FOSL1 | FOS-like antigen 1 | 0.023665 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0236338 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0234931 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0234017 |
| PLEC | plectin | 0.0232887 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0231388 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0228223 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0219377 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0218618 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0218495 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0216425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.217235 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.206256 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.140339 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.112977 |
| SDC4 | syndecan 4 | -0.0861402 |
| ENO1 | enolase 1, (alpha) | -0.0861396 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0842303 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0787601 |
| VIM | vimentin | -0.0761726 |
| VCL | vinculin | -0.0756999 |
| AHNAK | AHNAK nucleoprotein | -0.0746057 |
| TMSB10 | thymosin beta 10 | -0.0727396 |
| PTMA | prothymosin, alpha | -0.067436 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0642622 |
| TPM4 | tropomyosin 4 | -0.0637028 |
| CALU | calumenin | -0.0578371 |
| COL1A2 | collagen, type I, alpha 2 | -0.0548423 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0508162 |
| ACTG1 | actin gamma 1 | -0.0505336 |
| PRSS23 | protease, serine, 23 | -0.0496152 |
| CANX | calnexin | -0.04878 |
| LOX | lysyl oxidase | -0.0468545 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0445926 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0438058 |
| COL3A1 | collagen, type III, alpha 1 | -0.0418256 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0412093 |
| COL1A1 | collagen, type I, alpha 1 | -0.0395543 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0381934 |
| SPAG9 | sperm associated antigen 9 | -0.0375584 |
| ANXA2 | annexin A2 | -0.036074 |
| HDLBP | high density lipoprotein binding protein | -0.0341761 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0337945 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0329446 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.032299 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0321372 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0317204 |
| PALLD | palladin, cytoskeletal associated protein | -0.0316575 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313848 |
| KYNU | kynureninase | -0.0311684 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.030717 |
| RPLP1 | ribosomal protein, large, P1 | -0.02991 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0293654 |
| WTAP | Wilms tumor 1 associated protein | -0.0285341 |
| SEPTIN7 | septin 7 | -0.0281136 |
| MAP4 | microtubule-associated protein 4 | -0.028089 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0280074 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.027625 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0276065 |
| FLNB | filamin B, beta | -0.0269423 |
| CALD1 | caldesmon 1 | -0.0267254 |
| FBN1 | fibrillin 1 | -0.0266725 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0266707 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0262516 |
| RAB10 | RAB10, member RAS oncogene family | -0.0261864 |
| TNNC1 | troponin C type 1 (slow) | -0.0260737 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0259378 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0258479 |
| PGK1 | phosphoglycerate kinase 1 | -0.0255092 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0254393 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0251653 |
| TXNIP | thioredoxin interacting protein | -0.0251537 |
| PTK2 | protein tyrosine kinase 2 | -0.0250476 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0250183 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.0249868 |
| CUL3 | cullin 3 | -0.0249135 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0248803 |
| HMGB2 | high mobility group box 2 | -0.0248152 |
| UTRN | utrophin | -0.0247058 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0245266 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0243848 |
| UBC | ubiquitin C | -0.0239251 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0239153 |
| CLTC | clathrin, heavy chain (Hc) | -0.0238782 |
| MEF2A | myocyte enhancer factor 2A | -0.0228955 |
| OXR1 | oxidation resistance 1 | -0.0228219 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0228171 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0227685 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0227423 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0218073 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0217658 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0217166 |
| PTGES2 | prostaglandin E synthase 2 | -0.0214709 |
| MYO1E | myosin IE | -0.0213554 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0212835 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0212199 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0211545 |
| RHEB | Ras homolog enriched in brain | -0.0210353 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0206521 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0206099 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0205567 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0204325 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0202872 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0201426 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0199212 |
| CUL4B | cullin 4B | -0.0198656 |
| JUN | jun proto-oncogene | -0.0198483 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0196821 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0196256 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0195477 |
| CREBBP | CREB binding protein | -0.0195467 |