| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.14778 |
| POTEF | POTE ankyrin domain family, member F | 0.125839 |
| CDH13 | cadherin 13 | 0.122794 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.109603 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0749727 |
| EGFR | epidermal growth factor receptor | 0.0732433 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0607757 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.058925 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0565319 |
| CANX | calnexin | 0.0547048 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.054678 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0542447 |
| TPM4 | tropomyosin 4 | 0.0538198 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0508782 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0503346 |
| CENPF | centromere protein F, 350/400kDa | 0.0486951 |
| COL5A1 | collagen, type V, alpha 1 | 0.046391 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0455762 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0454275 |
| ASPH | aspartate beta-hydroxylase | 0.0442493 |
| TPM3 | tropomyosin 3 | 0.0436598 |
| CALR | calreticulin | 0.0418803 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0412972 |
| AHNAK | AHNAK nucleoprotein | 0.0412176 |
| HDAC9 | histone deacetylase 9 | 0.0408463 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0404575 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0358978 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0358322 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0356544 |
| DCLK2 | doublecortin-like kinase 2 | 0.0340037 |
| RND3 | Rho family GTPase 3 | 0.0339211 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0337189 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0334985 |
| COPA | coatomer protein complex, subunit alpha | 0.0330348 |
| PKM | pyruvate kinase, muscle | 0.0325734 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0310782 |
| EFNA5 | ephrin-A5 | 0.0306799 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.03051 |
| FOSL1 | FOS-like antigen 1 | 0.0302378 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0298492 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0298148 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0292259 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0287478 |
| DSPP | dentin sialophosphoprotein | 0.0282028 |
| ENO1 | enolase 1, (alpha) | 0.028189 |
| FAM107B | family with sequence similarity 107, member B | 0.0281049 |
| GOLGB1 | golgin B1 | 0.0276179 |
| MSN | moesin | 0.0276127 |
| FN1 | fibronectin 1 | 0.0273193 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0268974 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.026118 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0259964 |
| ANKRD30B | ankyrin repeat domain 30B | 0.0256904 |
| FTL | ferritin, light polypeptide | 0.0242934 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0239727 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0237287 |
| SET | SET nuclear proto-oncogene | 0.0235834 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0234507 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0230336 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0224798 |
| JUN | jun proto-oncogene | 0.0222281 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | 0.0221694 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0221075 |
| NDRG1 | N-myc downstream regulated 1 | 0.0220523 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0220123 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0217216 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0214312 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0210002 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0207866 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0205147 |
| SEPTIN7 | septin 7 | 0.0204401 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0203441 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0203358 |
| INTS6 | integrator complex subunit 6 | 0.0198741 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0197277 |
| CSTB | cystatin B (stefin B) | 0.0196844 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0192076 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0191724 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0191446 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0187961 |
| FMN2 | formin 2 | 0.0187747 |
| MSI2 | musashi RNA-binding protein 2 | 0.0186875 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0186458 |
| HDGF | hepatoma-derived growth factor | 0.0184613 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | 0.0179141 |
| MCL1 | myeloid cell leukemia 1 | 0.0178993 |
| AXL | AXL receptor tyrosine kinase | 0.0177862 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.017778 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0177511 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0177254 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0177241 |
| ERBIN | erbb2 interacting protein | 0.0176024 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.017468 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0174487 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0172127 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.0171843 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0171217 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0170643 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0170383 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0170077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.238059 |
| TMSB10 | thymosin beta 10 | -0.204885 |
| MT2A | metallothionein 2A | -0.163711 |
| FBN1 | fibrillin 1 | -0.160899 |
| LOX | lysyl oxidase | -0.120055 |
| COL1A2 | collagen, type I, alpha 2 | -0.112395 |
| COL3A1 | collagen, type III, alpha 1 | -0.108348 |
| CD44 | CD44 molecule (Indian blood group) | -0.100628 |
| LOXL2 | lysyl oxidase-like 2 | -0.0829014 |
| THBS2 | thrombospondin 2 | -0.0808646 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0745735 |
| HLA-B | major histocompatibility complex, class I, B | -0.0720964 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0715971 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0692587 |
| GPC6 | glypican 6 | -0.0692439 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0688919 |
| COL5A2 | collagen, type V, alpha 2 | -0.0685067 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0673136 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0669762 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0645706 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0608697 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0591133 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0546517 |
| HLA-C | major histocompatibility complex, class I, C | -0.0526505 |
| GLIS3 | GLIS family zinc finger 3 | -0.0511284 |
| PLAT | plasminogen activator, tissue | -0.0510572 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0489448 |
| AUTS2 | autism susceptibility candidate 2 | -0.0480589 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.046259 |
| CTSB | cathepsin B | -0.0460573 |
| MX2 | MX dynamin-like GTPase 2 | -0.0458223 |
| UBC | ubiquitin C | -0.045138 |
| STC1 | stanniocalcin 1 | -0.0444505 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0433619 |
| PRSS23 | protease, serine, 23 | -0.0431794 |
| B2M | beta-2-microglobulin | -0.0416318 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.041236 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0412118 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0411357 |
| MT1X | metallothionein 1X | -0.0391646 |
| S100A4 | S100 calcium binding protein A4 | -0.0385863 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0382051 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0380069 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0379361 |
| FRMD5 | FERM domain containing 5 | -0.0367584 |
| ADAR | adenosine deaminase, RNA-specific | -0.0364137 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0360192 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0354843 |
| ANXA2 | annexin A2 | -0.0351286 |
| SBF2 | SET binding factor 2 | -0.0344639 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0342412 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0340023 |
| MEIS2 | Meis homeobox 2 | -0.0333273 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0333243 |
| ATP13A3 | ATPase type 13A3 | -0.0332194 |
| TMSB4X | thymosin beta 4, X-linked | -0.0326051 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0323968 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0316285 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0316228 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0314604 |
| KIFAP3 | kinesin-associated protein 3 | -0.0312522 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0310954 |
| TUBB | tubulin, beta class I | -0.0309707 |
| OGA | O-GlcNAcase | -0.0301428 |
| FRMD4A | FERM domain containing 4A | -0.0297127 |
| RIGI | RNA sensor RIG-I | -0.0297057 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0296675 |
| NAV1 | neuron navigator 1 | -0.0295075 |
| NF1 | neurofibromin 1 | -0.0291759 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0290998 |
| CAVIN1 | caveolae associated protein 1 | -0.0290784 |
| TMOD1 | tropomodulin 1 | -0.0290609 |
| TRIM22 | tripartite motif containing 22 | -0.028724 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0285355 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0285332 |
| PXDN | peroxidasin | -0.0284261 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0283599 |
| WTAP | Wilms tumor 1 associated protein | -0.0279886 |
| EHBP1 | EH domain binding protein 1 | -0.0279106 |
| MAP4 | microtubule-associated protein 4 | -0.027556 |
| TDRD7 | tudor domain containing 7 | -0.0274157 |
| LRRC49 | leucine rich repeat containing 49 | -0.0273677 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0272714 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0271372 |
| PODXL | podocalyxin-like | -0.0270394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0269589 |
| HLA-E | major histocompatibility complex, class I, E | -0.0268872 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0267734 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0262167 |
| SDC4 | syndecan 4 | -0.0259049 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0256362 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0253656 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0250772 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0246334 |
| NPR2 | natriuretic peptide receptor 2 | -0.0243458 |
| ACTN4 | actinin, alpha 4 | -0.0240999 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.024 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0234746 |
| MB21D2 | Mab-21 domain containing 2 | -0.0231904 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.02309 |
