| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.299012 |
| POTEF | POTE ankyrin domain family, member F | 0.175531 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.147309 |
| EFNA5 | ephrin-A5 | 0.116139 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.107066 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.091135 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0856029 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0794465 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0748835 |
| PKM | pyruvate kinase, muscle | 0.0736119 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0700546 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0682998 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0656759 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0636346 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.06274 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.062632 |
| VMP1 | vacuole membrane protein 1 | 0.0611543 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0593289 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0591708 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0589857 |
| ANXA1 | annexin A1 | 0.0568393 |
| LDHA | lactate dehydrogenase A | 0.0566517 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0556117 |
| AXL | AXL receptor tyrosine kinase | 0.0550813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0548198 |
| VIM | vimentin | 0.053586 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0510295 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.050879 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0496346 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0494834 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0485184 |
| RHCG | Rh family, C glycoprotein | 0.0485157 |
| FAM107B | family with sequence similarity 107, member B | 0.0463482 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0460223 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0457576 |
| SMYD3 | SET and MYND domain containing 3 | 0.0455617 |
| MCL1 | myeloid cell leukemia 1 | 0.0453282 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0434533 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0434267 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0432656 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0431156 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0426321 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0424687 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0419265 |
| KYNU | kynureninase | 0.0403182 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0402522 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0400214 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0399869 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0392861 |
| MYO9A | myosin IXA | 0.0392641 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0388326 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0381867 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0380357 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0380055 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0377089 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0376716 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0371579 |
| EZR | ezrin | 0.0369849 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0369555 |
| DST | dystonin | 0.0361893 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0356967 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0355888 |
| GOLGB1 | golgin B1 | 0.0352415 |
| FAT1 | FAT atypical cadherin 1 | 0.0350525 |
| BPTF | bromodomain PHD finger transcription factor | 0.0348567 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0348534 |
| PCBP2 | poly(rC) binding protein 2 | 0.0343976 |
| TAOK1 | TAO kinase 1 | 0.034175 |
| CCDC88A | coiled-coil domain containing 88A | 0.0341311 |
| EXOC6B | exocyst complex component 6B | 0.0338617 |
| ZNF638 | zinc finger protein 638 | 0.0337439 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0332585 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0331971 |
| MYADM | myeloid-associated differentiation marker | 0.03225 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0321544 |
| DSTN | destrin (actin depolymerizing factor) | 0.0317589 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0311695 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0307732 |
| AHNAK | AHNAK nucleoprotein | 0.0307451 |
| SET | SET nuclear proto-oncogene | 0.0303788 |
| PDZD8 | PDZ domain containing 8 | 0.0299228 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0296028 |
| RPS2 | ribosomal protein S2 | 0.0294481 |
| HDGF | hepatoma-derived growth factor | 0.0293566 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0291995 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0287648 |
| CA12 | carbonic anhydrase XII | 0.0286534 |
| PCM1 | pericentriolar material 1 | 0.0284194 |
| TPM3 | tropomyosin 3 | 0.0283696 |
| DSPP | dentin sialophosphoprotein | 0.0283592 |
| ZNF148 | zinc finger protein 148 | 0.0281534 |
| RASAL2 | RAS protein activator like 2 | 0.0278026 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0277362 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0275959 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0274679 |
| RAB10 | RAB10, member RAS oncogene family | 0.0273557 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0273317 |
| IPO7 | importin 7 | 0.0271424 |
| RND3 | Rho family GTPase 3 | 0.0270768 |
| FAM13A | family with sequence similarity 13, member A | 0.0269944 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.248919 |
| MT2A | metallothionein 2A | -0.151218 |
| NDRG1 | N-myc downstream regulated 1 | -0.109684 |
| MT1X | metallothionein 1X | -0.105839 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0951912 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0925428 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0833347 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0773061 |
| PDE10A | phosphodiesterase 10A | -0.0769529 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0653443 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0590173 |
| RNF213 | ring finger protein 213 | -0.0557761 |
| RPS19 | ribosomal protein S19 | -0.0554283 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0552102 |
| OSMR | oncostatin M receptor | -0.0542449 |
| ACTG1 | actin gamma 1 | -0.0539193 |
| EXT1 | exostosin glycosyltransferase 1 | -0.052391 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0511824 |
| ACTN4 | actinin, alpha 4 | -0.0495596 |
| VCL | vinculin | -0.0494094 |
| FTL | ferritin, light polypeptide | -0.048011 |
| TNS3 | tensin 3 | -0.0473501 |
| RRBP1 | ribosome binding protein 1 | -0.0472192 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0458201 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0436205 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0425107 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0420384 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0414955 |
| RIN2 | Ras and Rab interactor 2 | -0.0407763 |
| RPL23 | ribosomal protein L23 | -0.0392312 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0383579 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0383474 |
| FLNA | filamin A, alpha | -0.0373403 |
| S100A6 | S100 calcium binding protein A6 | -0.0370827 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0366983 |
| PTMA | prothymosin, alpha | -0.0361575 |
| USP3 | ubiquitin specific peptidase 3 | -0.0360417 |
| TPM1 | tropomyosin 1 (alpha) | -0.0355081 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0349535 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0346953 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0345034 |
| BMERB1 | bMERB domain containing 1 | -0.0344428 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0339904 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0335703 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0328429 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0322752 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0320321 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0316356 |
| RPL35A | ribosomal protein L35a | -0.0304871 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0304437 |
| RPS21 | ribosomal protein S21 | -0.0298121 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0294559 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0293942 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0291619 |
| RPL13A | ribosomal protein L13a | -0.02912 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0287361 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0286401 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0282932 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0280485 |
| RPLP2 | ribosomal protein, large, P2 | -0.0280368 |
| RPS24 | ribosomal protein S24 | -0.0276153 |
| RPL37A | ribosomal protein L37a | -0.0270921 |
| TMSB4X | thymosin beta 4, X-linked | -0.026669 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0261605 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0254051 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0253691 |
| AUTS2 | autism susceptibility candidate 2 | -0.0252578 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | -0.0252038 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0243102 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0242976 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0241359 |
| RAI14 | retinoic acid induced 14 | -0.0236351 |
| NPC1 | Niemann-Pick disease, type C1 | -0.023595 |
| GNAS | GNAS complex locus | -0.0235163 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0234411 |
| RPL36 | ribosomal protein L36 | -0.0231067 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0230465 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0228947 |
| DAPK1 | death-associated protein kinase 1 | -0.0223812 |
| RPL32 | ribosomal protein L32 | -0.022187 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | -0.0221266 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0220852 |
| RPL26 | ribosomal protein L26 | -0.0219811 |
| RPS3 | ribosomal protein S3 | -0.0217618 |
| KIAA1217 | KIAA1217 | -0.0215519 |
| YBX3 | Y box binding protein 3 | -0.0213817 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0213231 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0213131 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0212581 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0212431 |
| ATG7 | autophagy related 7 | -0.0212062 |
| GPC6 | glypican 6 | -0.0210854 |
| PDE7B | phosphodiesterase 7B | -0.0210155 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0208903 |
| GLIS3 | GLIS family zinc finger 3 | -0.0207078 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0206785 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0205294 |
| NRP1 | neuropilin 1 | -0.0204423 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.020411 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0203501 |
