| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VMP1 | vacuole membrane protein 1 | 0.112737 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.109875 |
| NCOA3 | nuclear receptor coactivator 3 | 0.107103 |
| NDRG1 | N-myc downstream regulated 1 | 0.0933524 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0890752 |
| INTS6 | integrator complex subunit 6 | 0.080859 |
| GRB10 | growth factor receptor-bound protein 10 | 0.079471 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0780748 |
| DTNA | dystrobrevin, alpha | 0.0703652 |
| YAP1 | Yes-associated protein 1 | 0.0659281 |
| CEP250 | centrosomal protein 250kDa | 0.0581922 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0579936 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0565482 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0563382 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0547831 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0517467 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0511701 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0500482 |
| RCOR1 | REST corepressor 1 | 0.048856 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0470347 |
| FOXO3 | forkhead box O3 | 0.0454929 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0441691 |
| RAD51B | RAD51 paralog B | 0.0435122 |
| VCL | vinculin | 0.0408925 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0407236 |
| MED13 | mediator complex subunit 13 | 0.0402472 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0401684 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0397741 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.039392 |
| ZNF292 | zinc finger protein 292 | 0.0393269 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0392079 |
| SBF2 | SET binding factor 2 | 0.0383084 |
| TPD52 | tumor protein D52 | 0.037802 |
| PRELID2 | PRELI domain containing 2 | 0.0374848 |
| MCL1 | myeloid cell leukemia 1 | 0.0372522 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0362798 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0362383 |
| RAB7A | RAB7A, member RAS oncogene family | 0.036113 |
| CCNY | cyclin Y | 0.036111 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0359001 |
| VEGFA | vascular endothelial growth factor A | 0.0357379 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0356979 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0353535 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0347115 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0346794 |
| DENND1A | DENN/MADD domain containing 1A | 0.0345526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0344766 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0343438 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0343423 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0342687 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0340529 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340304 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0339277 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0339195 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0336153 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0335913 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0334646 |
| RTN3 | reticulon 3 | 0.0329144 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0326912 |
| ATF6 | activating transcription factor 6 | 0.0326695 |
| UBAP2 | ubiquitin associated protein 2 | 0.0325435 |
| PARD3 | par-3 family cell polarity regulator | 0.0324636 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0323725 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0323574 |
| HELZ | helicase with zinc finger | 0.0318779 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317262 |
| FAM168A | family with sequence similarity 168, member A | 0.0314441 |
| FNBP1L | formin binding protein 1-like | 0.0313499 |
| RUNX1 | runt-related transcription factor 1 | 0.0312078 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.031074 |
| BBX | bobby sox homolog (Drosophila) | 0.0310737 |
| PLSCR2 | phospholipid scramblase 2 | 0.0310604 |
| SPAG9 | sperm associated antigen 9 | 0.0309146 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0308599 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0308508 |
| FAM219A | family with sequence similarity 219, member A | 0.0307079 |
| ATXN1 | ataxin 1 | 0.0302871 |
| KRT86 | keratin 86, type II | 0.030236 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0301614 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0299578 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0299327 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0297074 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0297054 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0296058 |
| ZNF207 | zinc finger protein 207 | 0.0295473 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0294487 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.029391 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0293349 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0290409 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0287724 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0287076 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0286662 |
| SRPK2 | SRSF protein kinase 2 | 0.0286355 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0285175 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0284252 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0283895 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0282786 |
| RBM47 | RNA binding motif protein 47 | 0.028183 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0278811 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0275682 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.16719 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.128558 |
| RPL19 | ribosomal protein L19 | -0.0974772 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0795902 |
| NTN4 | netrin 4 | -0.0757823 |
| PTMA | prothymosin, alpha | -0.0703345 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.069537 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0675211 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0631923 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0627319 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0618511 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0609253 |
| OSMR | oncostatin M receptor | -0.0601487 |
| MT2A | metallothionein 2A | -0.0589652 |
| TMSB10 | thymosin beta 10 | -0.0560054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0537496 |
| ANKRD36C | ankyrin repeat domain 36C | -0.0536384 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0534268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0519247 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0505431 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0496815 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0487412 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.048602 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0485021 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0483522 |
| TMSB4X | thymosin beta 4, X-linked | -0.0472269 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0471776 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0462879 |
| CCND1 | cyclin D1 | -0.0460784 |
| ASPH | aspartate beta-hydroxylase | -0.0445316 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0440992 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0436132 |
| RPS3 | ribosomal protein S3 | -0.0433526 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0417835 |
| RPL12 | ribosomal protein L12 | -0.0410089 |
| KAZN | kazrin, periplakin interacting protein | -0.0393896 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0390622 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0386402 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0383667 |
| B2M | beta-2-microglobulin | -0.0372027 |
| S100A9 | S100 calcium binding protein A9 | -0.0370814 |
| TMC5 | transmembrane channel-like 5 | -0.0356703 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0356679 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0342192 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0330611 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0325614 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.032555 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0324985 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0319616 |
| LASP1 | LIM and SH3 protein 1 | -0.0319168 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0316124 |
| INSR | insulin receptor | -0.0309914 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0308704 |
| HLA-C | major histocompatibility complex, class I, C | -0.0306078 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0301728 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0299254 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0296084 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0293289 |
| S100A8 | S100 calcium binding protein A8 | -0.0291737 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | -0.0287386 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0286738 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0281284 |
| S100A14 | S100 calcium binding protein A14 | -0.0274352 |
| KLF6 | Kruppel-like factor 6 | -0.0270115 |
| CDK12 | cyclin-dependent kinase 12 | -0.0269453 |
| GATA3 | GATA binding protein 3 | -0.0268933 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.026854 |
| KRT19 | keratin 19, type I | -0.0267176 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0262972 |
| TMEM45B | transmembrane protein 45B | -0.0262929 |
| CCNI | cyclin I | -0.0256865 |
| RPS19 | ribosomal protein S19 | -0.0246163 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0245392 |
| GLCCI1 | glucocorticoid induced 1 | -0.0244283 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.024361 |
| RPL35A | ribosomal protein L35a | -0.0243225 |
| S100A6 | S100 calcium binding protein A6 | -0.0242784 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0241819 |
| RPS8 | ribosomal protein S8 | -0.0240602 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0238511 |
| TC2N | tandem C2 domains, nuclear | -0.023672 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0235936 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0235391 |
| CD63 | CD63 molecule | -0.0233446 |
| KRT18 | keratin 18, type I | -0.0231424 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0230833 |
| SMIM14 | small integral membrane protein 14 | -0.0229922 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | -0.0228674 |
| UBC | ubiquitin C | -0.0228292 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0225782 |
| CALR | calreticulin | -0.0220865 |
| NRCAM | neuronal cell adhesion molecule | -0.0219901 |
| ANKRD30A | ankyrin repeat domain 30A | -0.0219694 |
| S100P | S100 calcium binding protein P | -0.0219621 |
| CFB | complement factor B | -0.021899 |
| RAD21 | RAD21 homolog (S. pombe) | -0.021864 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0216557 |
| SDC4 | syndecan 4 | -0.0210666 |
| CD164 | CD164 molecule, sialomucin | -0.0210499 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0209742 |
