| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.168541 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.113633 |
| VCL | vinculin | 0.112721 |
| LSAMP | limbic system-associated membrane protein | 0.0885123 |
| NRG1 | neuregulin 1 | 0.0857081 |
| VMP1 | vacuole membrane protein 1 | 0.0669767 |
| TLE4 | transducin-like enhancer of split 4 | 0.0650047 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0649994 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.062415 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0531276 |
| SMYD3 | SET and MYND domain containing 3 | 0.0526983 |
| PRKCA | protein kinase C, alpha | 0.0522999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0519125 |
| CRH | corticotropin releasing hormone | 0.051035 |
| FERMT2 | fermitin family member 2 | 0.0505453 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0499879 |
| TENM4 | teneurin transmembrane protein 4 | 0.0483485 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.045768 |
| ZNF638 | zinc finger protein 638 | 0.0454112 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.043825 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0424647 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0423252 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0421198 |
| SET | SET nuclear proto-oncogene | 0.0418408 |
| MEIS2 | Meis homeobox 2 | 0.0417018 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.039991 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0390656 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0382644 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0379052 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0375202 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0368921 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0368784 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0367399 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0365952 |
| PLAT | plasminogen activator, tissue | 0.0364303 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0361369 |
| DNM3 | dynamin 3 | 0.0350417 |
| TPM1 | tropomyosin 1 (alpha) | 0.0342416 |
| EFNA5 | ephrin-A5 | 0.034207 |
| RAD51B | RAD51 paralog B | 0.0341598 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0341186 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0334633 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0334614 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0333449 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0332271 |
| EXOC4 | exocyst complex component 4 | 0.0332053 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.032796 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0326439 |
| AUTS2 | autism susceptibility candidate 2 | 0.0325149 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0324223 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0323199 |
| PHF14 | PHD finger protein 14 | 0.0315759 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0313595 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0309971 |
| GOLGB1 | golgin B1 | 0.0309341 |
| INTS6 | integrator complex subunit 6 | 0.0309112 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0307344 |
| HIP1 | huntingtin interacting protein 1 | 0.03044 |
| R3HDM2 | R3H domain containing 2 | 0.0302714 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0300038 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0299775 |
| TRIM24 | tripartite motif containing 24 | 0.0297303 |
| RBM20 | RNA binding motif protein 20 | 0.0294685 |
| CUX1 | cut-like homeobox 1 | 0.0294548 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.029327 |
| SBF2 | SET binding factor 2 | 0.0293067 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0284665 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0277787 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.027548 |
| TCF12 | transcription factor 12 | 0.0272034 |
| PCBP3 | poly(rC) binding protein 3 | 0.0270951 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0270241 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0266445 |
| HOMER1 | homer scaffolding protein 1 | 0.0265397 |
| COL5A1 | collagen, type V, alpha 1 | 0.0263675 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0261474 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0261317 |
| FN1 | fibronectin 1 | 0.025978 |
| DST | dystonin | 0.0253723 |
| CCDC57 | coiled-coil domain containing 57 | 0.025367 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0251153 |
| CDH13 | cadherin 13 | 0.0250223 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0242575 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0238452 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0236563 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0235258 |
| MBTD1 | mbt domain containing 1 | 0.0232986 |
| EXOC6B | exocyst complex component 6B | 0.0231332 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0231204 |
| FBXO11 | F-box protein 11 | 0.0229668 |
| SPOP | speckle-type POZ protein | 0.022844 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0227823 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0227457 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0226998 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0226854 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0226095 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0225604 |
| SKIL | SKI-like proto-oncogene | 0.0225371 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0224031 |
| INSIG2 | insulin induced gene 2 | 0.0222405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.263987 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19377 |
| IGF2 | insulin-like growth factor 2 | -0.17329 |
| VIM | vimentin | -0.113834 |
| MAP1B | microtubule-associated protein 1B | -0.0917063 |
| PTMA | prothymosin, alpha | -0.0893547 |
| TRIB2 | tribbles pseudokinase 2 | -0.0727582 |
| COL1A1 | collagen, type I, alpha 1 | -0.0616576 |
| TMSB10 | thymosin beta 10 | -0.0493979 |
| RPS24 | ribosomal protein S24 | -0.048714 |
| ANXA2 | annexin A2 | -0.0474112 |
| NF1 | neurofibromin 1 | -0.0439889 |
| COL3A1 | collagen, type III, alpha 1 | -0.0426 |
| RPL38 | ribosomal protein L38 | -0.0419817 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0386247 |
| RPL23 | ribosomal protein L23 | -0.0383079 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0365038 |
| TBX2 | T-box 2 | -0.0358302 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0349772 |
| RPS6 | ribosomal protein S6 | -0.033407 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0332686 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0331186 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0327144 |
| RPS19 | ribosomal protein S19 | -0.0307416 |
| RPL35A | ribosomal protein L35a | -0.030456 |
| RPL4 | ribosomal protein L4 | -0.0302249 |
| FRMD4A | FERM domain containing 4A | -0.0292592 |
| ACTG1 | actin gamma 1 | -0.0289104 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0287899 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0283413 |
| WDR45B | WD repeat domain 45B | -0.0283111 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0279776 |
| RNF213 | ring finger protein 213 | -0.0275032 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0270629 |
| LMNA | lamin A/C | -0.0265407 |
| FTL | ferritin, light polypeptide | -0.0265253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0265058 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0264699 |
| ZNF292 | zinc finger protein 292 | -0.0254428 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0250078 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0248738 |
| MEF2A | myocyte enhancer factor 2A | -0.0248194 |
| RPL34 | ribosomal protein L34 | -0.0248161 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0247349 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0246957 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0246573 |
| RPL32 | ribosomal protein L32 | -0.0245179 |
| H3-3B | H3.3 histone B | -0.0245042 |
| RPS5 | ribosomal protein S5 | -0.0241168 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0241059 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0240497 |
| CSNK1G1 | casein kinase 1, gamma 1 | -0.0232681 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.023263 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0229012 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0228103 |
| S100A6 | S100 calcium binding protein A6 | -0.0227541 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.022631 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0221984 |
| RHOA | ras homolog family member A | -0.0218951 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0218339 |
| RPS3 | ribosomal protein S3 | -0.0213813 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0213615 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0212377 |
| S100A9 | S100 calcium binding protein A9 | -0.0211576 |
| MED13L | mediator complex subunit 13-like | -0.0209974 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0209764 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0208305 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0207405 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0207194 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0201352 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0200295 |
| RPL7A | ribosomal protein L7a | -0.0199575 |
| SYT1 | synaptotagmin I | -0.0199351 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0198685 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0198386 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0198329 |
| PFN1 | profilin 1 | -0.019805 |
| GOLGA4 | golgin A4 | -0.0196918 |
| ADAR | adenosine deaminase, RNA-specific | -0.019604 |
| NDRG1 | N-myc downstream regulated 1 | -0.0194631 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0194285 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0194014 |
| INTS2 | integrator complex subunit 2 | -0.0193793 |
| SP100 | SP100 nuclear antigen | -0.0191625 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0190975 |
| GNAS | GNAS complex locus | -0.0190535 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | -0.0189672 |
| SEPTIN2 | septin 2 | -0.0186013 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0185781 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0185494 |
| RPS17 | ribosomal protein S17 | -0.018526 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0184395 |
| PRR11 | proline rich 11 | -0.01843 |
| JMJD1C | jumonji domain containing 1C | -0.0183763 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0183263 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0180536 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0180381 |
| TKT | transketolase | -0.0180111 |
| FOXO3 | forkhead box O3 | -0.0179852 |
| TUBB | tubulin, beta class I | -0.0178521 |
