| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.314561 |
| CANX | calnexin | 0.0916445 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0885306 |
| GOLGA4 | golgin A4 | 0.08464 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.075905 |
| PRELID2 | PRELI domain containing 2 | 0.0754311 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0731961 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0710986 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0707055 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0706869 |
| ZNF638 | zinc finger protein 638 | 0.068935 |
| MORF4L2 | mortality factor 4 like 2 | 0.0662663 |
| PCBP2 | poly(rC) binding protein 2 | 0.0612016 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0607286 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0594878 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0548167 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0527756 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0522564 |
| GOLGB1 | golgin B1 | 0.0518702 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0507566 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.048775 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0486731 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0478445 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0452803 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0449743 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0445164 |
| INTS6 | integrator complex subunit 6 | 0.0429978 |
| ATF4 | activating transcription factor 4 | 0.0414694 |
| EZR | ezrin | 0.0412107 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0410198 |
| VMP1 | vacuole membrane protein 1 | 0.0402355 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0395382 |
| TXNRD1 | thioredoxin reductase 1 | 0.0393844 |
| POTEF | POTE ankyrin domain family, member F | 0.0386352 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0379766 |
| SQSTM1 | sequestosome 1 | 0.0378636 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0377164 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0372886 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0371538 |
| NUCB2 | nucleobindin 2 | 0.037026 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0368557 |
| COG6 | component of oligomeric golgi complex 6 | 0.0368276 |
| NKTR | natural killer cell triggering receptor | 0.0368255 |
| CDK19 | cyclin-dependent kinase 19 | 0.0357835 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0357753 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0356668 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0356096 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0353754 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0348703 |
| SUCO | SUN domain containing ossification factor | 0.0347474 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.03464 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0338291 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0335452 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0335349 |
| TMF1 | TATA element modulatory factor 1 | 0.0333981 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0332186 |
| TFG | TRK-fused gene | 0.0328256 |
| BPTF | bromodomain PHD finger transcription factor | 0.0327573 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0321842 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0319201 |
| YBX1 | Y box binding protein 1 | 0.0318098 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0311489 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0308908 |
| JMJD1C | jumonji domain containing 1C | 0.0307942 |
| RPL11 | ribosomal protein L11 | 0.0305625 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0303996 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0303264 |
| C6ORF62 | chromosome 6 open reading frame 62 | 0.0303157 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0299814 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0292868 |
| COG5 | component of oligomeric golgi complex 5 | 0.0291622 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0289541 |
| ASPH | aspartate beta-hydroxylase | 0.028886 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.028268 |
| SRP54 | signal recognition particle 54kDa | 0.0280807 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0280488 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0276916 |
| USO1 | USO1 vesicle transport factor | 0.0276265 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0275476 |
| USP53 | ubiquitin specific peptidase 53 | 0.0275411 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0273863 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0271654 |
| TAOK3 | TAO kinase 3 | 0.0271078 |
| VIM | vimentin | 0.0270124 |
| JUN | jun proto-oncogene | 0.0269098 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0268563 |
| BBX | bobby sox homolog (Drosophila) | 0.0266741 |
| USP37 | ubiquitin specific peptidase 37 | 0.0264768 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0262701 |
| OGA | O-GlcNAcase | 0.0262677 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0262179 |
| RPS14 | ribosomal protein S14 | 0.0262047 |
| BRD2 | bromodomain containing 2 | 0.0261009 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0260833 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0258889 |
| INSIG2 | insulin induced gene 2 | 0.0258565 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0258471 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0257703 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0257431 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0256561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | -0.178184 |
| NDRG1 | N-myc downstream regulated 1 | -0.173055 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.10325 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.087023 |
| AHNAK | AHNAK nucleoprotein | -0.0787538 |
| PTMA | prothymosin, alpha | -0.0732223 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0707654 |
| TPM4 | tropomyosin 4 | -0.0703675 |
| WWOX | WW domain containing oxidoreductase | -0.060359 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0556569 |
| KRT18 | keratin 18, type I | -0.0507928 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0503904 |
| PLEC | plectin | -0.0479875 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0473095 |
| FHIT | fragile histidine triad | -0.0456518 |
| CCND1 | cyclin D1 | -0.0451494 |
| SH3BP4 | SH3-domain binding protein 4 | -0.0435156 |
| RPL4 | ribosomal protein L4 | -0.0434377 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0427963 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0405211 |
| HLA-B | major histocompatibility complex, class I, B | -0.0382293 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0361092 |
| CDCP1 | CUB domain containing protein 1 | -0.0359075 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0358151 |
| RPS27A | ribosomal protein S27a | -0.0356757 |
| SETD5 | SET domain containing 5 | -0.0354985 |
| PAQR5 | progestin and adipoQ receptor family member V | -0.0354281 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0353478 |
| ITGB4 | integrin, beta 4 | -0.0332675 |
| KRT19 | keratin 19, type I | -0.032436 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0317328 |
| HLA-A | major histocompatibility complex, class I, A | -0.030975 |
| VDAC1 | voltage-dependent anion channel 1 | -0.030895 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0306734 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0295027 |
| SBF2 | SET binding factor 2 | -0.028911 |
| HMGA1 | high mobility group AT-hook 1 | -0.0288168 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0287539 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0285856 |
| PDS5A | PDS5 cohesin associated factor A | -0.0283623 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0283589 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.027813 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0277846 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0273146 |
| TMEM51 | transmembrane protein 51 | -0.0271048 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0268319 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0267611 |
| TCF20 | transcription factor 20 (AR1) | -0.0266159 |
| ANXA3 | annexin A3 | -0.0266075 |
| RPS16 | ribosomal protein S16 | -0.0265359 |
| FRMD5 | FERM domain containing 5 | -0.0264783 |
| UBC | ubiquitin C | -0.0262524 |
| PKM | pyruvate kinase, muscle | -0.0259966 |
| TNS4 | tensin 4 | -0.0259477 |
| CUX1 | cut-like homeobox 1 | -0.0257919 |
| APP | amyloid beta (A4) precursor protein | -0.0257689 |
| DIAPH2 | diaphanous-related formin 2 | -0.0256921 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0253765 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.025358 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0252966 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0252489 |
| KRT8 | keratin 8, type II | -0.0250995 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0250113 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0247818 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0247257 |
| RPL38 | ribosomal protein L38 | -0.0245429 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0244211 |
| PRRC2A | proline-rich coiled-coil 2A | -0.0242832 |
| YEATS2 | YEATS domain containing 2 | -0.0242783 |
| TMEM123 | transmembrane protein 123 | -0.024249 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0241846 |
| EREG | epiregulin | -0.0241632 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240729 |
| ARFGEF3 | ARFGEF family member 3 | -0.0236655 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0235429 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.023033 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0229074 |
| CBFB | core-binding factor, beta subunit | -0.0227415 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0227067 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0224542 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0221524 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0221233 |
| RPL35 | ribosomal protein L35 | -0.0220173 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0218939 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0218573 |
| ZNF33A | zinc finger protein 33A | -0.0216932 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0215791 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0211887 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0209951 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0209149 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0208802 |
| PALD1 | phosphatase domain containing, paladin 1 | -0.0207914 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0207714 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0207393 |
| ACTN4 | actinin, alpha 4 | -0.0205887 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0205609 |
| ZNF609 | zinc finger protein 609 | -0.0204735 |
| HMGA2 | high mobility group AT-hook 2 | -0.0203973 |
| FBL | fibrillarin | -0.0203441 |
| FOSL1 | FOS-like antigen 1 | -0.0203375 |
