| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.227752 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.198093 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.110902 |
| ASPH | aspartate beta-hydroxylase | 0.106456 |
| LAMB3 | laminin, beta 3 | 0.0940956 |
| CANX | calnexin | 0.0873959 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0776015 |
| AHNAK | AHNAK nucleoprotein | 0.0773013 |
| SET | SET nuclear proto-oncogene | 0.0616503 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0587735 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0585795 |
| PTMA | prothymosin, alpha | 0.0560297 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.055961 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0536134 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0534636 |
| APP | amyloid beta (A4) precursor protein | 0.053411 |
| LAMA4 | laminin, alpha 4 | 0.0531126 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0521603 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0515851 |
| ANXA2 | annexin A2 | 0.0502399 |
| RPS6 | ribosomal protein S6 | 0.0501058 |
| ENO1 | enolase 1, (alpha) | 0.0473413 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0471282 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0463651 |
| LDHA | lactate dehydrogenase A | 0.045133 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0446153 |
| GOLGA4 | golgin A4 | 0.0435985 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0432464 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0428492 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0421115 |
| CALR | calreticulin | 0.0418978 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0418088 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0417191 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0415643 |
| CDK13 | cyclin-dependent kinase 13 | 0.0410691 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0409813 |
| HMGA2 | high mobility group AT-hook 2 | 0.0402766 |
| GOLGB1 | golgin B1 | 0.0400525 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0351187 |
| DSG2 | desmoglein 2 | 0.0349467 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0345248 |
| TES | testin LIM domain protein | 0.0343875 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0340055 |
| TPM4 | tropomyosin 4 | 0.0339641 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0335792 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0335091 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 0.0333314 |
| ANXA1 | annexin A1 | 0.0331219 |
| EMP1 | epithelial membrane protein 1 | 0.0330568 |
| LAMC2 | laminin, gamma 2 | 0.032465 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0323802 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0317912 |
| DSPP | dentin sialophosphoprotein | 0.031654 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0314784 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0311428 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0309476 |
| JMJD1C | jumonji domain containing 1C | 0.0307526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0300586 |
| RPS8 | ribosomal protein S8 | 0.0299924 |
| EHBP1 | EH domain binding protein 1 | 0.0293457 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0292609 |
| RPS2 | ribosomal protein S2 | 0.0290555 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0285997 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0285601 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0285054 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280297 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0273261 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0273244 |
| EZR | ezrin | 0.0270147 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0269222 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0260998 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0260568 |
| CD2AP | CD2-associated protein | 0.0259653 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0259337 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0258525 |
| SQSTM1 | sequestosome 1 | 0.02559 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0254398 |
| NF1 | neurofibromin 1 | 0.0252702 |
| TMSB4X | thymosin beta 4, X-linked | 0.0251212 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0251202 |
| RPL14 | ribosomal protein L14 | 0.0250584 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0248209 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0247682 |
| TPM3 | tropomyosin 3 | 0.0246908 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0246723 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0246266 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0246076 |
| TPR | translocated promoter region, nuclear basket protein | 0.0245742 |
| CD44 | CD44 molecule (Indian blood group) | 0.0244789 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0241134 |
| EGFR | epidermal growth factor receptor | 0.0238753 |
| TMF1 | TATA element modulatory factor 1 | 0.023834 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0232906 |
| ECT2 | epithelial cell transforming 2 | 0.0232888 |
| SVIL | supervillin | 0.0232014 |
| INTS6 | integrator complex subunit 6 | 0.0231686 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0229264 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0228589 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0227265 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0225399 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146435 |
| FTL | ferritin, light polypeptide | -0.0943346 |
| MT2A | metallothionein 2A | -0.0878263 |
| EGR1 | early growth response 1 | -0.067493 |
| RPS19 | ribosomal protein S19 | -0.0609662 |
| TMSB10 | thymosin beta 10 | -0.0589007 |
| ACTG1 | actin gamma 1 | -0.0569892 |
| FOSL1 | FOS-like antigen 1 | -0.0495994 |
| RPLP2 | ribosomal protein, large, P2 | -0.0486033 |
| ITGB8 | integrin, beta 8 | -0.0470658 |
| RPL28 | ribosomal protein L28 | -0.0458711 |
| MT1X | metallothionein 1X | -0.045249 |
| RPL32 | ribosomal protein L32 | -0.0437287 |
| RPS11 | ribosomal protein S11 | -0.036063 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0358651 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0351627 |
| SNX9 | sorting nexin 9 | -0.0332582 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0324381 |
| CLDN4 | claudin 4 | -0.0318299 |
| FLNA | filamin A, alpha | -0.0316907 |
| CCNL1 | cyclin L1 | -0.0316351 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0311955 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0301218 |
| B2M | beta-2-microglobulin | -0.0293217 |
| RPS13 | ribosomal protein S13 | -0.0292851 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0289639 |
| ICAM1 | intercellular adhesion molecule 1 | -0.028324 |
| PFN1 | profilin 1 | -0.0281326 |
| CDCP1 | CUB domain containing protein 1 | -0.0280008 |
| TAPBP | TAP binding protein (tapasin) | -0.027709 |
| TPI1 | triosephosphate isomerase 1 | -0.027659 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0266887 |
| PCBP2 | poly(rC) binding protein 2 | -0.0265863 |
| RPS21 | ribosomal protein S21 | -0.026548 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0256416 |
| RPLP1 | ribosomal protein, large, P1 | -0.0256309 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0255314 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0253434 |
| AGRN | agrin | -0.0246471 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0244278 |
| RPL35 | ribosomal protein L35 | -0.0243602 |
| LOC112694756 | uncharaterized LOC112694756 | -0.024249 |
| RPS5 | ribosomal protein S5 | -0.0241493 |
| RPS23 | ribosomal protein S23 | -0.0232947 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0231193 |
| AXL | AXL receptor tyrosine kinase | -0.0228395 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0227077 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0224294 |
| CAPNS1 | calpain, small subunit 1 | -0.0223616 |
| RPS15 | ribosomal protein S15 | -0.0219144 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0218127 |
| RPL8 | ribosomal protein L8 | -0.0217872 |
| RPS29 | ribosomal protein S29 | -0.0210425 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | -0.0205815 |
| BCL2L1 | BCL2-like 1 | -0.0205158 |
| RPS16 | ribosomal protein S16 | -0.0198549 |
| RPS4X | ribosomal protein S4, X-linked | -0.0193604 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0188625 |
| LAMA5 | laminin, alpha 5 | -0.0187077 |
| RPL19 | ribosomal protein L19 | -0.0183954 |
| PKM | pyruvate kinase, muscle | -0.0181016 |
| CCNI | cyclin I | -0.0180327 |
| KIF18B | kinesin family member 18B | -0.0178812 |
| WASF2 | WAS protein family, member 2 | -0.0178795 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0172719 |
| BARD1 | BRCA1 associated RING domain 1 | -0.0172698 |
| FOXM1 | forkhead box M1 | -0.0171639 |
| RNF213 | ring finger protein 213 | -0.0170747 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0169303 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0168422 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0167128 |
| TAGLN2 | transgelin 2 | -0.0162518 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -0.0162062 |
| RPLP0 | ribosomal protein, large, P0 | -0.0159323 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0158816 |
| RPS10 | ribosomal protein S10 | -0.0158783 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0158579 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0158256 |
| TNPO3 | transportin 3 | -0.0157427 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0156866 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0154479 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0154271 |
| S100A9 | S100 calcium binding protein A9 | -0.0153929 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.015266 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0152518 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0152157 |
| GPX4 | glutathione peroxidase 4 | -0.0150651 |
| TUBA1B | tubulin, alpha 1b | -0.0147589 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0147014 |
| H3-3B | H3.3 histone B | -0.0146905 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0146097 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0146039 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0144423 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.0143777 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0141114 |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | -0.0140936 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0140829 |
| ADAR | adenosine deaminase, RNA-specific | -0.014051 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0140451 |
| RPL21 | ribosomal protein L21 | -0.0139901 |
