| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.146108 |
| LMO7 | LIM domain 7 | 0.107351 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0981285 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0940467 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0858834 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0796785 |
| B2M | beta-2-microglobulin | 0.0675725 |
| RPS12 | ribosomal protein S12 | 0.0669316 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0643194 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0614407 |
| KRT20 | keratin 20, type I | 0.058052 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0510396 |
| AREG | amphiregulin | 0.0492709 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0491202 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0462784 |
| EMP1 | epithelial membrane protein 1 | 0.0439273 |
| RPS2 | ribosomal protein S2 | 0.0433981 |
| ASPH | aspartate beta-hydroxylase | 0.0426364 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0409875 |
| PGK1 | phosphoglycerate kinase 1 | 0.0388572 |
| DST | dystonin | 0.0387826 |
| SET | SET nuclear proto-oncogene | 0.0384139 |
| RIGI | RNA sensor RIG-I | 0.0368157 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0365779 |
| RPS6 | ribosomal protein S6 | 0.0360667 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0347641 |
| EXPH5 | exophilin 5 | 0.0345914 |
| RAD21 | RAD21 homolog (S. pombe) | 0.033928 |
| RPS3 | ribosomal protein S3 | 0.0323487 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.032025 |
| CANX | calnexin | 0.0313872 |
| GOLGB1 | golgin B1 | 0.0311412 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0310173 |
| APOL1 | apolipoprotein L, 1 | 0.0304119 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0300062 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0299693 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0296693 |
| TMC5 | transmembrane channel-like 5 | 0.0294316 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0290834 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0289464 |
| HMGB2 | high mobility group box 2 | 0.0287937 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0285243 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0282104 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0278335 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0276194 |
| RPL31 | ribosomal protein L31 | 0.0275464 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0272041 |
| PLK2 | polo-like kinase 2 | 0.027139 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0269855 |
| NUCB2 | nucleobindin 2 | 0.0266709 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0265042 |
| RND3 | Rho family GTPase 3 | 0.0256412 |
| ENO1 | enolase 1, (alpha) | 0.025452 |
| ANXA1 | annexin A1 | 0.0254293 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0253349 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0251594 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0250797 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0247247 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0239574 |
| POF1B | premature ovarian failure, 1B | 0.0237498 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0234122 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0233316 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0229999 |
| VIM | vimentin | 0.0229998 |
| RPL37A | ribosomal protein L37a | 0.0229747 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0227824 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0225481 |
| SLFN5 | schlafen family member 5 | 0.0224551 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0223674 |
| FRY | furry homolog (Drosophila) | 0.0222581 |
| KLF6 | Kruppel-like factor 6 | 0.0219554 |
| GLCCI1 | glucocorticoid induced 1 | 0.0216884 |
| NEBL | nebulette | 0.0216548 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0215588 |
| LAMB3 | laminin, beta 3 | 0.0215236 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.0214598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0211309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0206162 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0204442 |
| RPS8 | ribosomal protein S8 | 0.0202899 |
| RPL26 | ribosomal protein L26 | 0.0202732 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0199738 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0197088 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0195741 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0195599 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0195417 |
| RACK1 | receptor for activated C kinase 1 | 0.0193507 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0191256 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0187289 |
| SMIM14 | small integral membrane protein 14 | 0.0184367 |
| SERINC1 | serine incorporator 1 | 0.0182486 |
| EGFR | epidermal growth factor receptor | 0.018085 |
| SGMS2 | sphingomyelin synthase 2 | 0.0180835 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0179777 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0179412 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0178688 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0178669 |
| LDHA | lactate dehydrogenase A | 0.0176988 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0174778 |
| MYADM | myeloid-associated differentiation marker | 0.0172418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.142965 |
| SLC45A4 | solute carrier family 45, member 4 | -0.130475 |
| ACTN4 | actinin, alpha 4 | -0.107208 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.102487 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0990541 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0948813 |
| WASF2 | WAS protein family, member 2 | -0.0923844 |
| FTL | ferritin, light polypeptide | -0.092335 |
| LYZ | lysozyme | -0.0904789 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0823415 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0809989 |
| STK24 | serine/threonine kinase 24 | -0.0809526 |
| PTK2 | protein tyrosine kinase 2 | -0.0785314 |
| ANXA2 | annexin A2 | -0.078305 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0761031 |
| TMSB10 | thymosin beta 10 | -0.0754748 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.075026 |
| NDRG1 | N-myc downstream regulated 1 | -0.0723519 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0657165 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0612603 |
| DNM2 | dynamin 2 | -0.0605369 |
| SMAD3 | SMAD family member 3 | -0.0604384 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0602506 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0599175 |
| KRT8 | keratin 8, type II | -0.0591649 |
| CTBP2 | C-terminal binding protein 2 | -0.0577937 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0571789 |
| RPS21 | ribosomal protein S21 | -0.0570759 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0569988 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0557825 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0557805 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0555187 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0548399 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0544371 |
| WWC1 | WW and C2 domain containing 1 | -0.0542943 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0535728 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0535368 |
| DGKH | diacylglycerol kinase, eta | -0.0530263 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0525144 |
| ANXA11 | annexin A11 | -0.0516482 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0514251 |
| JUP | junction plakoglobin | -0.0510351 |
| NF1 | neurofibromin 1 | -0.0499927 |
| ZNF207 | zinc finger protein 207 | -0.0498054 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0497629 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0487967 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0485566 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0484276 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0476582 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0476223 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0475264 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0473783 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0466307 |
| GSE1 | Gse1 coiled-coil protein | -0.0455474 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0451033 |
| USP3 | ubiquitin specific peptidase 3 | -0.045047 |
| ACTG1 | actin gamma 1 | -0.044957 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0446756 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0446714 |
| RHEB | Ras homolog enriched in brain | -0.0446561 |
| TMEM65 | transmembrane protein 65 | -0.0441404 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0437421 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0427494 |
| KRT18 | keratin 18, type I | -0.0427301 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0423287 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0420358 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0417068 |
| COG5 | component of oligomeric golgi complex 5 | -0.0413974 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0407598 |
| KIAA0232 | KIAA0232 | -0.0405497 |
| ABLIM1 | actin binding LIM protein 1 | -0.040364 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0401309 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0400562 |
| RPLP2 | ribosomal protein, large, P2 | -0.0399395 |
| TMEM123 | transmembrane protein 123 | -0.0398616 |
| RPS19 | ribosomal protein S19 | -0.0391736 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0386378 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0383616 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0381516 |
| S100A6 | S100 calcium binding protein A6 | -0.0381444 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0376446 |
| SBF2 | SET binding factor 2 | -0.0376224 |
| HMGA1 | high mobility group AT-hook 1 | -0.0373365 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0370155 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0367755 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0366945 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0365451 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0363453 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0361929 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0360487 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0356026 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.035147 |
| PKP4 | plakophilin 4 | -0.0350004 |
| SEPTIN9 | septin 9 | -0.0347098 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.034078 |
| MYO1E | myosin IE | -0.0337551 |
| TJP2 | tight junction protein 2 | -0.0334661 |
| VCL | vinculin | -0.0332687 |
| ASTN2 | astrotactin 2 | -0.0332382 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0324934 |
