| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.131727 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.10365 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0853242 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0716571 |
| TLE4 | transducin-like enhancer of split 4 | 0.0698974 |
| NAV2 | neuron navigator 2 | 0.066595 |
| POTEF | POTE ankyrin domain family, member F | 0.0660054 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0621207 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0599459 |
| ASPH | aspartate beta-hydroxylase | 0.0576871 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0486738 |
| DST | dystonin | 0.0465315 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0457935 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0456322 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0449266 |
| SMYD3 | SET and MYND domain containing 3 | 0.0444336 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0430063 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0425311 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0410212 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.040637 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0402908 |
| UBAP2 | ubiquitin associated protein 2 | 0.0394051 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0391892 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0384272 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0382875 |
| RAD51B | RAD51 paralog B | 0.038183 |
| ATXN1 | ataxin 1 | 0.0380692 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0373887 |
| AEBP2 | AE binding protein 2 | 0.036966 |
| PRELID2 | PRELI domain containing 2 | 0.0367154 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0364567 |
| VCL | vinculin | 0.0364178 |
| FNIP1 | folliculin interacting protein 1 | 0.0359345 |
| FHIT | fragile histidine triad | 0.0357253 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0352148 |
| RPS6 | ribosomal protein S6 | 0.0351653 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0343593 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.034127 |
| EGFR | epidermal growth factor receptor | 0.033202 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0329565 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0324695 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0324108 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0316634 |
| CLIC4 | chloride intracellular channel 4 | 0.0315783 |
| EFNA5 | ephrin-A5 | 0.0315691 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0314136 |
| GOLGB1 | golgin B1 | 0.0313262 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0312754 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0310109 |
| RIGI | RNA sensor RIG-I | 0.0309378 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0308508 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0306908 |
| DTNA | dystrobrevin, alpha | 0.0304768 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.029694 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0296689 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0295543 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0289014 |
| KLF12 | Kruppel-like factor 12 | 0.0281849 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0277011 |
| FN1 | fibronectin 1 | 0.0273539 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0270108 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0267598 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0264693 |
| HDAC9 | histone deacetylase 9 | 0.0260899 |
| RSU1 | Ras suppressor protein 1 | 0.0258506 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0258125 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0258084 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | 0.0256235 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0256137 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0254378 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0254248 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0250236 |
| CMIP | c-Maf inducing protein | 0.0248949 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0248044 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0246432 |
| NABP1 | nucleic acid binding protein 1 | 0.0244536 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0242484 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0242309 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0238525 |
| RGS7 | regulator of G-protein signaling 7 | 0.0238186 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0236641 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0233343 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0231621 |
| CUX1 | cut-like homeobox 1 | 0.0229723 |
| MT2A | metallothionein 2A | 0.0229138 |
| RASAL2 | RAS protein activator like 2 | 0.0227493 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0227216 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0226778 |
| WWOX | WW domain containing oxidoreductase | 0.022609 |
| BPTF | bromodomain PHD finger transcription factor | 0.0225937 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0224115 |
| EXOC4 | exocyst complex component 4 | 0.0222717 |
| RUNX1 | runt-related transcription factor 1 | 0.0220571 |
| SETX | senataxin | 0.021789 |
| ZNF638 | zinc finger protein 638 | 0.0217369 |
| CORO1C | coronin, actin binding protein, 1C | 0.0214949 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0214359 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0213219 |
| ZNF804A | zinc finger protein 804A | 0.0210318 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.021019 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.267085 |
| HLA-B | major histocompatibility complex, class I, B | -0.146216 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.110273 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0989155 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0978075 |
| ATP13A3 | ATPase type 13A3 | -0.0901406 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0900795 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0756201 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0724508 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0661823 |
| TXNRD1 | thioredoxin reductase 1 | -0.0658073 |
| HLA-C | major histocompatibility complex, class I, C | -0.059862 |
| CD44 | CD44 molecule (Indian blood group) | -0.0593369 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0584887 |
| OSMR | oncostatin M receptor | -0.0576717 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0573248 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0557153 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0512156 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0496402 |
| ANXA2 | annexin A2 | -0.0484151 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0452918 |
| TMSB4X | thymosin beta 4, X-linked | -0.0452831 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0447564 |
| TUBB | tubulin, beta class I | -0.0446837 |
| ANKRD10 | ankyrin repeat domain 10 | -0.044193 |
| HLA-A | major histocompatibility complex, class I, A | -0.0432326 |
| ADM | adrenomedullin | -0.0432202 |
| FLNB | filamin B, beta | -0.0430812 |
| NDRG1 | N-myc downstream regulated 1 | -0.0426881 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0421938 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0421319 |
| ZNF841 | zinc finger protein 841 | -0.0416871 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0416736 |
| HLA-E | major histocompatibility complex, class I, E | -0.0413307 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0412198 |
| TMEM41B | transmembrane protein 41B | -0.0411125 |
| PGK1 | phosphoglycerate kinase 1 | -0.0409846 |
| ARF4 | ADP-ribosylation factor 4 | -0.0404246 |
| CALR | calreticulin | -0.0379223 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0352356 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0351204 |
| CTSD | cathepsin D | -0.033266 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0330571 |
| POSTN | periostin, osteoblast specific factor | -0.0324646 |
| NUP58 | nucleoporin 58 | -0.0310165 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0309432 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0308859 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0302978 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0295698 |
| TGFB2 | transforming growth factor, beta 2 | -0.0293126 |
| AFAP1 | actin filament associated protein 1 | -0.0290815 |
| GLIS3 | GLIS family zinc finger 3 | -0.028923 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0288262 |
| RLF | rearranged L-myc fusion | -0.0287439 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.0285081 |
| LDHA | lactate dehydrogenase A | -0.0283492 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0276612 |
| ZFR | zinc finger RNA binding protein | -0.0271015 |
| ENO1 | enolase 1, (alpha) | -0.0268104 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0266601 |
| TRAM2 | translocation associated membrane protein 2 | -0.0262424 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0260795 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0255045 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0253855 |
| GNAS | GNAS complex locus | -0.0249437 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0243044 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.024273 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0242146 |
| PLCB4 | phospholipase C, beta 4 | -0.0240112 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) | -0.0236055 |
| MYLK | myosin light chain kinase | -0.023539 |
| UBC | ubiquitin C | -0.0235269 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0234846 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0232753 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.02321 |
| DENND4C | DENN/MADD domain containing 4C | -0.0231969 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.02309 |
| TPD52 | tumor protein D52 | -0.0230515 |
| FSTL1 | follistatin-like 1 | -0.023025 |
| CALU | calumenin | -0.02289 |
| COL5A1 | collagen, type V, alpha 1 | -0.0228845 |
| KIAA1958 | KIAA1958 | -0.0225467 |
| S100A6 | S100 calcium binding protein A6 | -0.0223741 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0223572 |
| STK4 | serine/threonine kinase 4 | -0.0222142 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0221194 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | -0.0220697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.02203 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0220258 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0218679 |
| GOLT1B | golgi transport 1B | -0.0218644 |
| FLNA | filamin A, alpha | -0.021749 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0216782 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0216261 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0215858 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0215347 |
| NUP153 | nucleoporin 153kDa | -0.0215054 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0213745 |
| TPI1 | triosephosphate isomerase 1 | -0.0213736 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.021299 |
