| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.094327 |
| GOLGA4 | golgin A4 | 0.0588429 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0482718 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0469223 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.045536 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0445315 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0387204 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0363605 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0350277 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0344187 |
| RBM25 | RNA binding motif protein 25 | 0.033791 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0337256 |
| PLAC8 | placenta-specific 8 | 0.0336437 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0335909 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0323629 |
| SETD5 | SET domain containing 5 | 0.0313253 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0301646 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0295221 |
| CALB1 | calbindin 1, 28kDa | 0.0291733 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0281642 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0275719 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0268994 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0257562 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0255517 |
| MYO6 | myosin VI | 0.025055 |
| NKTR | natural killer cell triggering receptor | 0.0249634 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0242434 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0239545 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0236725 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0230069 |
| TMEM41B | transmembrane protein 41B | 0.022959 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0227481 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0223468 |
| TMF1 | TATA element modulatory factor 1 | 0.0220965 |
| LRRC1 | leucine rich repeat containing 1 | 0.0218159 |
| CDK19 | cyclin-dependent kinase 19 | 0.0213816 |
| PTEN | phosphatase and tensin homolog | 0.0211267 |
| RIN2 | Ras and Rab interactor 2 | 0.0208455 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0207041 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0205445 |
| AFDN | afadin, adherens junction formation factor | 0.0203853 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0200572 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0199253 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0196707 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0193731 |
| GDF15 | growth differentiation factor 15 | 0.0192269 |
| CLINT1 | clathrin interactor 1 | 0.0190277 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0189523 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0189466 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0188678 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0188613 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.018734 |
| COPA | coatomer protein complex, subunit alpha | 0.0184343 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0183961 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0183249 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0182726 |
| NRDC | nardilysin convertase | 0.0181343 |
| SRP54 | signal recognition particle 54kDa | 0.0180515 |
| YBX3 | Y box binding protein 3 | 0.0174824 |
| XPOT | exportin, tRNA | 0.0173518 |
| RBM39 | RNA binding motif protein 39 | 0.0173392 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0173363 |
| THOC2 | THO complex 2 | 0.0172898 |
| TRIM31 | tripartite motif containing 31 | 0.0171827 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0171809 |
| MLEC | malectin | 0.0171674 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0170697 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0169707 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0168934 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0168119 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0167763 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0166083 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0165884 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0164576 |
| CEP95 | centrosomal protein 95kDa | 0.0164265 |
| EZR | ezrin | 0.0163877 |
| ZNF292 | zinc finger protein 292 | 0.0163051 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0162629 |
| CCPG1 | cell cycle progression 1 | 0.016203 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0160949 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0160874 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.0157998 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.0156265 |
| ZNF638 | zinc finger protein 638 | 0.0155937 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0155 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0152832 |
| SUCO | SUN domain containing ossification factor | 0.0151328 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0150555 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0149688 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0146901 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0144931 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0144616 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0144412 |
| CARD16 | caspase recruitment domain family, member 16 | 0.014313 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0141557 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0141422 |
| UBN2 | ubinuclein 2 | 0.014027 |
| ARF4 | ADP-ribosylation factor 4 | 0.0139842 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0138497 |
| USO1 | USO1 vesicle transport factor | 0.0138465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.216627 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.183374 |
| LMO7 | LIM domain 7 | -0.166667 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.147783 |
| MYO1E | myosin IE | -0.132751 |
| RPLP1 | ribosomal protein, large, P1 | -0.127568 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.106673 |
| KRT18 | keratin 18, type I | -0.0863331 |
| ACTG1 | actin gamma 1 | -0.0856597 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0821931 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0770719 |
| RPS23 | ribosomal protein S23 | -0.076452 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0761979 |
| RPL34 | ribosomal protein L34 | -0.0709268 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0695197 |
| ANXA2 | annexin A2 | -0.0690915 |
| RPLP2 | ribosomal protein, large, P2 | -0.0640472 |
| RPS25 | ribosomal protein S25 | -0.0629639 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0625734 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0610948 |
| RPLP0 | ribosomal protein, large, P0 | -0.0605709 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0605522 |
| FRMD5 | FERM domain containing 5 | -0.0582131 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0559174 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0546781 |
| RPL4 | ribosomal protein L4 | -0.05455 |
| PKM | pyruvate kinase, muscle | -0.0535026 |
| RPS13 | ribosomal protein S13 | -0.052804 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0524652 |
| RPS19 | ribosomal protein S19 | -0.0514578 |
| KRT8 | keratin 8, type II | -0.0491473 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0483825 |
| RPS24 | ribosomal protein S24 | -0.047914 |
| FBXO11 | F-box protein 11 | -0.0470891 |
| SERINC5 | serine incorporator 5 | -0.0462802 |
| RPS21 | ribosomal protein S21 | -0.0461483 |
| RPS16 | ribosomal protein S16 | -0.0457997 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0454749 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.045247 |
| SP100 | SP100 nuclear antigen | -0.0446319 |
| MYO5B | myosin VB | -0.0442549 |
| RPS8 | ribosomal protein S8 | -0.0441581 |
| DSG2 | desmoglein 2 | -0.0437305 |
| RPL28 | ribosomal protein L28 | -0.0436656 |
| TJP1 | tight junction protein 1 | -0.042927 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0426199 |
| CUX1 | cut-like homeobox 1 | -0.0425316 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0421764 |
| RPL8 | ribosomal protein L8 | -0.0413766 |
| RPS11 | ribosomal protein S11 | -0.0413449 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.040858 |
| CLIC5 | chloride intracellular channel 5 | -0.040837 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0398037 |
| OXSR1 | oxidative stress responsive 1 | -0.0397026 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0396951 |
| EGFR | epidermal growth factor receptor | -0.0395149 |
| CTBP2 | C-terminal binding protein 2 | -0.039167 |
| INTS6 | integrator complex subunit 6 | -0.0389375 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0385231 |
| FHIT | fragile histidine triad | -0.0385155 |
| RPS20 | ribosomal protein S20 | -0.038104 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0379716 |
| ABLIM1 | actin binding LIM protein 1 | -0.0379141 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0377741 |
| RPL12 | ribosomal protein L12 | -0.0376361 |
| RPS27A | ribosomal protein S27a | -0.0373603 |
| RPS14 | ribosomal protein S14 | -0.0371503 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0367388 |
| RPS15 | ribosomal protein S15 | -0.0367102 |
| UBC | ubiquitin C | -0.0366867 |
| RPS6 | ribosomal protein S6 | -0.0365926 |
| RPL19 | ribosomal protein L19 | -0.0365417 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0364654 |
| RPS5 | ribosomal protein S5 | -0.0361962 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0357312 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0353186 |
| RACK1 | receptor for activated C kinase 1 | -0.0346639 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0344611 |
| DST | dystonin | -0.0342138 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0339731 |
| LDHA | lactate dehydrogenase A | -0.0337918 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0337135 |
| DENND1A | DENN/MADD domain containing 1A | -0.0332317 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.033121 |
| RPL37 | ribosomal protein L37 | -0.0327973 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0327713 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0325653 |
| SVIL | supervillin | -0.0325077 |
| TMSB10 | thymosin beta 10 | -0.0323961 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0322217 |
| HLA-B | major histocompatibility complex, class I, B | -0.0321472 |
| RPL27A | ribosomal protein L27a | -0.0317462 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0316546 |
| RPL32 | ribosomal protein L32 | -0.0313118 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0312333 |
| PALLD | palladin, cytoskeletal associated protein | -0.0308559 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0308216 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0305231 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0304194 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0300983 |
