| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0745134 |
| LAMA4 | laminin, alpha 4 | 0.0660625 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0626857 |
| SCEL | sciellin | 0.0490385 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.048601 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.048167 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0457992 |
| AREG | amphiregulin | 0.0446597 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0436425 |
| GRAMD1B | GRAM domain containing 1B | 0.0433544 |
| MT2A | metallothionein 2A | 0.0429764 |
| LAMC2 | laminin, gamma 2 | 0.041818 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0415898 |
| AHNAK | AHNAK nucleoprotein | 0.0409912 |
| TES | testin LIM domain protein | 0.0407532 |
| SMYD3 | SET and MYND domain containing 3 | 0.0396326 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0392459 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0390436 |
| DSPP | dentin sialophosphoprotein | 0.0360544 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0357649 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.034123 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0336643 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0329482 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.032459 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0324092 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0311093 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0304512 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0301323 |
| ASPH | aspartate beta-hydroxylase | 0.0300933 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0296697 |
| TOP1 | topoisomerase (DNA) I | 0.0291791 |
| OSMR | oncostatin M receptor | 0.0280603 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0279725 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0274322 |
| EFNA5 | ephrin-A5 | 0.0273577 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0271819 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0271718 |
| SLTM | SAFB-like, transcription modulator | 0.0267174 |
| LMO7 | LIM domain 7 | 0.0265507 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0260066 |
| FOXP1 | forkhead box P1 | 0.0248508 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.024748 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0241982 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0240926 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240709 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0239677 |
| YBX3 | Y box binding protein 3 | 0.0238664 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0235778 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0234027 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0232839 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0231677 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0221859 |
| NRDC | nardilysin convertase | 0.0213414 |
| LIPH | lipase, member H | 0.0206682 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0201954 |
| ANXA1 | annexin A1 | 0.0201831 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0195866 |
| NTN4 | netrin 4 | 0.0195681 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0195089 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0193981 |
| SON | SON DNA binding protein | 0.0193256 |
| OXSR1 | oxidative stress responsive 1 | 0.0192777 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0192395 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0191516 |
| EXOC6B | exocyst complex component 6B | 0.0190906 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0189938 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0189585 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0186418 |
| RNF213 | ring finger protein 213 | 0.018402 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0183714 |
| EMP1 | epithelial membrane protein 1 | 0.0182379 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0182078 |
| VMP1 | vacuole membrane protein 1 | 0.018041 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0177553 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0176947 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0176011 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0175832 |
| FMN1 | formin 1 | 0.0175062 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0174833 |
| TRIM56 | tripartite motif containing 56 | 0.0174522 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0173284 |
| RAB10 | RAB10, member RAS oncogene family | 0.0172907 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0172807 |
| SYAP1 | synapse associated protein 1 | 0.0172155 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0170492 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0166942 |
| CANX | calnexin | 0.0166482 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0164245 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0163634 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0163488 |
| RBM25 | RNA binding motif protein 25 | 0.0162518 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0160358 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0160122 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0159712 |
| DST | dystonin | 0.0158183 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.0158096 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0157508 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0157005 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0156355 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.0155983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.420795 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.179909 |
| EGFR | epidermal growth factor receptor | -0.165605 |
| NDRG1 | N-myc downstream regulated 1 | -0.148264 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0983733 |
| TMSB10 | thymosin beta 10 | -0.0881295 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0775669 |
| EGR1 | early growth response 1 | -0.0759771 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0748223 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0742444 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0686968 |
| SMAD3 | SMAD family member 3 | -0.0639006 |
| S100A10 | S100 calcium binding protein A10 | -0.0600778 |
| PTMA | prothymosin, alpha | -0.0592536 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0576091 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0548871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0525893 |
| FAM13A | family with sequence similarity 13, member A | -0.052508 |
| PKM | pyruvate kinase, muscle | -0.0515198 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0494453 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0481303 |
| WASF2 | WAS protein family, member 2 | -0.0468477 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0454531 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0445114 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0441193 |
| ARRDC3 | arrestin domain containing 3 | -0.0438227 |
| TMEM165 | transmembrane protein 165 | -0.0423518 |
| RPS25 | ribosomal protein S25 | -0.0420491 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0416869 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0407779 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0404843 |
| PDE8A | phosphodiesterase 8A | -0.040405 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0397633 |
| RPS24 | ribosomal protein S24 | -0.0392053 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0390738 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0378285 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0375984 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0375419 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0373649 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0350697 |
| H1-0 | H1.0 linker histone | -0.0347789 |
| RPL35A | ribosomal protein L35a | -0.0346616 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.034623 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0346137 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345445 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0345302 |
| UBC | ubiquitin C | -0.0343335 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.03411 |
| ACTG1 | actin gamma 1 | -0.0340939 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.034044 |
| GPC6 | glypican 6 | -0.0323874 |
| NGLY1 | N-glycanase 1 | -0.0320619 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0318436 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0307686 |
| WDR45B | WD repeat domain 45B | -0.0302845 |
| TPD52 | tumor protein D52 | -0.0300302 |
| SQSTM1 | sequestosome 1 | -0.0298831 |
| HLA-B | major histocompatibility complex, class I, B | -0.0291972 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0291363 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0288705 |
| HELZ | helicase with zinc finger | -0.0287005 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0278196 |
| MCL1 | myeloid cell leukemia 1 | -0.0275603 |
| RPS23 | ribosomal protein S23 | -0.0273875 |
| HOOK2 | hook microtubule-tethering protein 2 | -0.0273439 |
| RPL34 | ribosomal protein L34 | -0.0266435 |
| CST3 | cystatin C | -0.0266275 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0265609 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0257669 |
| PLEC | plectin | -0.0257478 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0253025 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0252822 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0251944 |
| IER3 | immediate early response 3 | -0.0249722 |
| HBP1 | HMG-box transcription factor 1 | -0.0247611 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0247598 |
| ENSA | endosulfine alpha | -0.0246492 |
| SEPTIN2 | septin 2 | -0.0246276 |
| S100A6 | S100 calcium binding protein A6 | -0.02418 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0238535 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0235295 |
| FUS | FUS RNA binding protein | -0.0230723 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0228564 |
| ANXA2 | annexin A2 | -0.0228522 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0227636 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0220391 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0219395 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0218356 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0216738 |
| UVRAG | UV radiation resistance associated | -0.0214139 |
| RPS29 | ribosomal protein S29 | -0.0213125 |
| HDLBP | high density lipoprotein binding protein | -0.0213105 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0211987 |
| SBF2 | SET binding factor 2 | -0.0211543 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0211258 |
| RPS21 | ribosomal protein S21 | -0.0210561 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0209177 |
| FNIP1 | folliculin interacting protein 1 | -0.0208131 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0206576 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0206539 |
