| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HMGA2 | high mobility group AT-hook 2 | 0.0576758 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0526928 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0523063 |
| NAV2 | neuron navigator 2 | 0.0498171 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0473413 |
| MT2A | metallothionein 2A | 0.0439969 |
| SMAD3 | SMAD family member 3 | 0.0435049 |
| ANKRD28 | ankyrin repeat domain 28 | 0.040526 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0385002 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0370005 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0363156 |
| PRELID2 | PRELI domain containing 2 | 0.036079 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0355886 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0354346 |
| ZNF638 | zinc finger protein 638 | 0.0349497 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0341202 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0339676 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0335153 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0330592 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0314411 |
| INTS6 | integrator complex subunit 6 | 0.0313913 |
| AADAC | arylacetamide deacetylase | 0.0313027 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.030447 |
| EFNA5 | ephrin-A5 | 0.0278255 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0252537 |
| EHBP1 | EH domain binding protein 1 | 0.0252138 |
| RAD51B | RAD51 paralog B | 0.0251208 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.024996 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0244721 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0243185 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0233752 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0233362 |
| TUT7 | terminal uridylyl transferase 7 | 0.0232593 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0230289 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0226644 |
| NTN4 | netrin 4 | 0.0219281 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0214012 |
| PHF14 | PHD finger protein 14 | 0.0205722 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0203963 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.020077 |
| ATXN1 | ataxin 1 | 0.0193437 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0189631 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0186668 |
| NEBL | nebulette | 0.018663 |
| RHCG | Rh family, C glycoprotein | 0.0184575 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0183627 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0180986 |
| WLS | wntless Wnt ligand secretion mediator | 0.0179481 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0176025 |
| SUMF1 | sulfatase modifying factor 1 | 0.0175812 |
| SYT1 | synaptotagmin I | 0.0174487 |
| MIPOL1 | mirror-image polydactyly 1 | 0.0171125 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0169466 |
| MYOF | myoferlin | 0.0168334 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0168055 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0166601 |
| GPC6 | glypican 6 | 0.0166433 |
| GPHN | gephyrin | 0.0166106 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0164495 |
| DST | dystonin | 0.0163722 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0163515 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0162138 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0161201 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0160551 |
| ANO6 | anoctamin 6 | 0.0160038 |
| RUNX1 | runt-related transcription factor 1 | 0.0159616 |
| UTRN | utrophin | 0.0159037 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0158909 |
| NABP1 | nucleic acid binding protein 1 | 0.0157953 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0157735 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0157712 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0157315 |
| SMYD3 | SET and MYND domain containing 3 | 0.0156745 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0156643 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0156473 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.015624 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0153287 |
| CAPRIN2 | caprin family member 2 | 0.0152213 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.0149894 |
| STK38L | serine/threonine kinase 38 like | 0.014878 |
| EGFR | epidermal growth factor receptor | 0.0148579 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0146096 |
| FNDC3A | fibronectin type III domain containing 3A | 0.014594 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0144926 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0144443 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0143971 |
| EZR | ezrin | 0.0143597 |
| KSR1 | kinase suppressor of ras 1 | 0.0143229 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0143102 |
| WWOX | WW domain containing oxidoreductase | 0.0142262 |
| USP53 | ubiquitin specific peptidase 53 | 0.0141375 |
| MEIS1 | Meis homeobox 1 | 0.0139804 |
| LOXL2 | lysyl oxidase-like 2 | 0.0139632 |
| NOTCH2 | notch 2 | 0.0138587 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0137141 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0131652 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0131579 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0130578 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0130043 |
| FHIT | fragile histidine triad | 0.0127634 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.197994 |
| TMSB10 | thymosin beta 10 | -0.138165 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113468 |
| UBC | ubiquitin C | -0.0928247 |
| PCBP2 | poly(rC) binding protein 2 | -0.0840129 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.08134 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0809692 |
| LOX | lysyl oxidase | -0.0755843 |
| STC1 | stanniocalcin 1 | -0.0733696 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0714587 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0711953 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0697847 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0665706 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0648024 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0639884 |
| ENO1 | enolase 1, (alpha) | -0.0626205 |
| PTMA | prothymosin, alpha | -0.0609521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0603873 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0513133 |
| CD44 | CD44 molecule (Indian blood group) | -0.0497283 |
| NDRG1 | N-myc downstream regulated 1 | -0.0485662 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0481166 |
| S100A6 | S100 calcium binding protein A6 | -0.0469976 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0448238 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0448221 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0430225 |
| OSMR | oncostatin M receptor | -0.0424562 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417488 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.040505 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.040308 |
| CDCP1 | CUB domain containing protein 1 | -0.0391806 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0378909 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0374635 |
| B2M | beta-2-microglobulin | -0.0373941 |
| MTSS1 | metastasis suppressor 1 | -0.0368144 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0366388 |
| CANX | calnexin | -0.036516 |
| RPS12 | ribosomal protein S12 | -0.0356914 |
| RAB1A | RAB1A, member RAS oncogene family | -0.035044 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0340394 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0339956 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0337706 |
| RAB27B | RAB27B, member RAS oncogene family | -0.033631 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0333332 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0332716 |
| MEF2A | myocyte enhancer factor 2A | -0.0314301 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.031399 |
| ATP13A3 | ATPase type 13A3 | -0.0313698 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0312949 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0312087 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0311522 |
| TMSB4X | thymosin beta 4, X-linked | -0.0310593 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0307823 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0307579 |
| NRG1 | neuregulin 1 | -0.0306851 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0303894 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0302192 |
| GOLGA4 | golgin A4 | -0.0301603 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0295383 |
| IL1B | interleukin 1, beta | -0.0292572 |
| LDHA | lactate dehydrogenase A | -0.029113 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0290823 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0288288 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0286406 |
| CALR | calreticulin | -0.0284051 |
| FTL | ferritin, light polypeptide | -0.0275521 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0274216 |
| HDLBP | high density lipoprotein binding protein | -0.0273797 |
| NAV3 | neuron navigator 3 | -0.0272397 |
| SNX9 | sorting nexin 9 | -0.0269987 |
| PKM | pyruvate kinase, muscle | -0.0269431 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0268412 |
| FN1 | fibronectin 1 | -0.0266772 |
| PGK1 | phosphoglycerate kinase 1 | -0.0266593 |
| CALU | calumenin | -0.0264719 |
| ETV6 | ets variant 6 | -0.0263821 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0263359 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | -0.0260964 |
| CLMP | CXADR-like membrane protein | -0.0258959 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0258137 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0258014 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0256788 |
| HPCAL1 | hippocalcin-like 1 | -0.0254957 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0254449 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0251951 |
| APP | amyloid beta (A4) precursor protein | -0.0251122 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0251042 |
| PRRX1 | paired related homeobox 1 | -0.0250936 |
| GLCCI1 | glucocorticoid induced 1 | -0.0247701 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245062 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0244617 |
| RIOK3 | RIO kinase 3 | -0.0243778 |
| RPS17 | ribosomal protein S17 | -0.0243264 |
| HMGA1 | high mobility group AT-hook 1 | -0.024116 |
| RPS3 | ribosomal protein S3 | -0.0239914 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0234632 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0233199 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0227235 |
| RAI14 | retinoic acid induced 14 | -0.0226226 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0225455 |
