| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.152607 |
| TENM3 | teneurin transmembrane protein 3 | 0.14259 |
| ZNF638 | zinc finger protein 638 | 0.141888 |
| ENO1 | enolase 1, (alpha) | 0.135529 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.11699 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.115124 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.108381 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.103263 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.100762 |
| TXNRD1 | thioredoxin reductase 1 | 0.0993799 |
| RPS12 | ribosomal protein S12 | 0.0992667 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0909984 |
| CARD16 | caspase recruitment domain family, member 16 | 0.089217 |
| IGF2 | insulin-like growth factor 2 | 0.0880231 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0879995 |
| RPS8 | ribosomal protein S8 | 0.0879051 |
| RPL31 | ribosomal protein L31 | 0.0867184 |
| MT2A | metallothionein 2A | 0.0849741 |
| CMIP | c-Maf inducing protein | 0.0844607 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0833782 |
| FTL | ferritin, light polypeptide | 0.0824272 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0815206 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0796784 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0756004 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0743189 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0739442 |
| DOCK5 | dedicator of cytokinesis 5 | 0.07106 |
| USP34 | ubiquitin specific peptidase 34 | 0.0668928 |
| TXNIP | thioredoxin interacting protein | 0.0668454 |
| SYT1 | synaptotagmin I | 0.0662026 |
| PKM | pyruvate kinase, muscle | 0.0660405 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0640488 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0617707 |
| INTS6 | integrator complex subunit 6 | 0.0577713 |
| SBF2 | SET binding factor 2 | 0.0552799 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0550517 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0545188 |
| PGK1 | phosphoglycerate kinase 1 | 0.0541804 |
| OXR1 | oxidation resistance 1 | 0.0539693 |
| RUNX1 | runt-related transcription factor 1 | 0.0529415 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0529406 |
| STK24 | serine/threonine kinase 24 | 0.0522591 |
| SQSTM1 | sequestosome 1 | 0.0521586 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0514278 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0508549 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0504092 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0465449 |
| MYOF | myoferlin | 0.044791 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0438823 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0435413 |
| RPS3 | ribosomal protein S3 | 0.0432297 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0430539 |
| EGR1 | early growth response 1 | 0.0428774 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0421923 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0415442 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0410627 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0404888 |
| DST | dystonin | 0.03962 |
| AHNAK | AHNAK nucleoprotein | 0.038968 |
| RPLP0 | ribosomal protein, large, P0 | 0.0388128 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0387629 |
| SMAD3 | SMAD family member 3 | 0.0383318 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0382501 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0380516 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0377662 |
| SPAG9 | sperm associated antigen 9 | 0.0376394 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0369892 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0357724 |
| RPS6 | ribosomal protein S6 | 0.0353029 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0341169 |
| FNIP1 | folliculin interacting protein 1 | 0.0335614 |
| GLG1 | golgi glycoprotein 1 | 0.0334345 |
| RPL26 | ribosomal protein L26 | 0.033427 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0311922 |
| LDHA | lactate dehydrogenase A | 0.0311769 |
| B2M | beta-2-microglobulin | 0.0306725 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0305218 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0302077 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0299859 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0287075 |
| EZR | ezrin | 0.0284623 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0276573 |
| INHBA | inhibin, beta A | 0.0271164 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.02673 |
| GOLGA4 | golgin A4 | 0.0264681 |
| ANXA2 | annexin A2 | 0.0264391 |
| TMSB10 | thymosin beta 10 | 0.026194 |
| OGA | O-GlcNAcase | 0.02435 |
| TPM4 | tropomyosin 4 | 0.0235666 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.023517 |
| FLNB | filamin B, beta | 0.023424 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0230576 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0229277 |
| EGFR | epidermal growth factor receptor | 0.0226504 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0221789 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0221029 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0217942 |
| RPL12 | ribosomal protein L12 | 0.0214249 |
| RPS24 | ribosomal protein S24 | 0.0213631 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0212392 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.153972 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.118528 |
| GPC6 | glypican 6 | -0.118417 |
| STC1 | stanniocalcin 1 | -0.116794 |
| EXT1 | exostosin glycosyltransferase 1 | -0.109574 |
| VIM | vimentin | -0.104398 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0994337 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0943443 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0922234 |
| MMP1 | matrix metallopeptidase 1 | -0.0831514 |
| JMJD1C | jumonji domain containing 1C | -0.082129 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0819768 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0763185 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0761798 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0738687 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.072391 |
| FRMD4A | FERM domain containing 4A | -0.0704798 |
| LAMB3 | laminin, beta 3 | -0.0700042 |
| MCL1 | myeloid cell leukemia 1 | -0.0684681 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0681705 |
| CDH13 | cadherin 13 | -0.0678908 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.066998 |
| RORA | RAR-related orphan receptor A | -0.0666713 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0644374 |
| PDE10A | phosphodiesterase 10A | -0.0637648 |
| PTK2 | protein tyrosine kinase 2 | -0.061956 |
| NDRG1 | N-myc downstream regulated 1 | -0.0615674 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.061535 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0608879 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0595764 |
| EFNA5 | ephrin-A5 | -0.0580629 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0569954 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0555636 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0525108 |
| VMP1 | vacuole membrane protein 1 | -0.0524574 |
| PTMA | prothymosin, alpha | -0.0524465 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0501344 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0490839 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.046619 |
| HDLBP | high density lipoprotein binding protein | -0.0465532 |
| PRKCA | protein kinase C, alpha | -0.0464646 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0462644 |
| FAM13A | family with sequence similarity 13, member A | -0.0462606 |
| SMYD3 | SET and MYND domain containing 3 | -0.0456148 |
| CLTC | clathrin, heavy chain (Hc) | -0.0449196 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0426557 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0425289 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0403785 |
| RCOR1 | REST corepressor 1 | -0.0383377 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0374455 |
| ATXN1 | ataxin 1 | -0.0355214 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0354584 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.034884 |
| PARD3 | par-3 family cell polarity regulator | -0.0344593 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0343474 |
| HELZ | helicase with zinc finger | -0.0336964 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0330501 |
| GLIS3 | GLIS family zinc finger 3 | -0.032918 |
| RPS19 | ribosomal protein S19 | -0.0322677 |
| MYO1E | myosin IE | -0.0317153 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0312624 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0311335 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0310714 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0296676 |
| MYO10 | myosin X | -0.0290181 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0290125 |
| RNF213 | ring finger protein 213 | -0.0284891 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0276741 |
| TES | testin LIM domain protein | -0.0272837 |
| SETD5 | SET domain containing 5 | -0.0263896 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.026334 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0262023 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0260184 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0257971 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0254408 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.025061 |
| RPL35A | ribosomal protein L35a | -0.0245946 |
| CUX1 | cut-like homeobox 1 | -0.02277 |
| LMNA | lamin A/C | -0.0215631 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0209629 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0203579 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0202898 |
| RBM39 | RNA binding motif protein 39 | -0.0202456 |
| DYM | dymeclin | -0.0190153 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0186538 |
| CD44 | CD44 molecule (Indian blood group) | -0.0184873 |
| CCNI | cyclin I | -0.018401 |
| FNDC3A | fibronectin type III domain containing 3A | -0.018087 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0176454 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0171749 |
| USP15 | ubiquitin specific peptidase 15 | -0.0165897 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0163034 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0160961 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0130549 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0129015 |
| CALR | calreticulin | -0.0124086 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0124056 |
| VCL | vinculin | -0.010962 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0104705 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0102869 |
