| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111433 |
| DST | dystonin | 0.108628 |
| TENM3 | teneurin transmembrane protein 3 | 0.086433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0699832 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0673608 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0653129 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0646059 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0556377 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0547963 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.054039 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.05276 |
| NTM | neurotrimin | 0.0510819 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0497469 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0476992 |
| CDK6 | cyclin-dependent kinase 6 | 0.0475888 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0449026 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0444698 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0428254 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0424084 |
| JMJD1C | jumonji domain containing 1C | 0.0422507 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.041537 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0404484 |
| PRR16 | proline rich 16 | 0.0378969 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0378949 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0371465 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.036975 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0366653 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0362243 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0359391 |
| WDR43 | WD repeat domain 43 | 0.0356988 |
| KIF5B | kinesin family member 5B | 0.0355616 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0352398 |
| SHROOM3 | shroom family member 3 | 0.0343641 |
| ZNF608 | zinc finger protein 608 | 0.034096 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0338548 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0337822 |
| FNBP1L | formin binding protein 1-like | 0.0334041 |
| MPG | N-methylpurine-DNA glycosylase | 0.0333871 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0333736 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0328679 |
| PDGFC | platelet derived growth factor C | 0.0323283 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0318865 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0313092 |
| MED13L | mediator complex subunit 13-like | 0.0310162 |
| MED12L | mediator complex subunit 12-like | 0.0307994 |
| RBM39 | RNA binding motif protein 39 | 0.030542 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0304746 |
| TNRC6A | trinucleotide repeat containing 6A | 0.030439 |
| FMNL2 | formin-like 2 | 0.0303467 |
| MEMO1 | mediator of cell motility 1 | 0.0300325 |
| RBM33 | RNA binding motif protein 33 | 0.0299605 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0296465 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0295985 |
| METAP2 | methionyl aminopeptidase 2 | 0.0295195 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0294453 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0292557 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0290203 |
| QKI | QKI, KH domain containing, RNA binding | 0.0288234 |
| SRPK2 | SRSF protein kinase 2 | 0.0285766 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0279912 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0277204 |
| CENPE | centromere protein E, 312kDa | 0.0276672 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0276294 |
| FBXO11 | F-box protein 11 | 0.0274964 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0274233 |
| POTEF | POTE ankyrin domain family, member F | 0.027421 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0272643 |
| CCDC102B | coiled-coil domain containing 102B | 0.0271648 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0271404 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0269867 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0269296 |
| PHF3 | PHD finger protein 3 | 0.0268486 |
| YAP1 | Yes-associated protein 1 | 0.0268033 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0266886 |
| RASAL2 | RAS protein activator like 2 | 0.0265796 |
| USP3 | ubiquitin specific peptidase 3 | 0.0265105 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0264191 |
| MKI67 | marker of proliferation Ki-67 | 0.0263632 |
| THBS1 | thrombospondin 1 | 0.0263387 |
| ENAH | enabled homolog (Drosophila) | 0.0262082 |
| FN1 | fibronectin 1 | 0.0259655 |
| NCKAP1 | NCK-associated protein 1 | 0.0259555 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0259379 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0259269 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0257895 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0257057 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0252769 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.025233 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0250292 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0249664 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0246409 |
| EVI5 | ecotropic viral integration site 5 | 0.0245418 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0244188 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0242877 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0242277 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0242029 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0240579 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 0.0240301 |
| PCDH7 | protocadherin 7 | 0.0238245 |
| PEG10 | paternally expressed 10 | 0.0237817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.12789 |
| VIM | vimentin | -0.126329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.125461 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10261 |
| TMSB10 | thymosin beta 10 | -0.0965115 |
| PCDH9 | protocadherin 9 | -0.0932211 |
| COL1A2 | collagen, type I, alpha 2 | -0.078766 |
| RPS16 | ribosomal protein S16 | -0.0747011 |
| COL3A1 | collagen, type III, alpha 1 | -0.0737721 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.065247 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0647396 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0639345 |
| SNX6 | sorting nexin 6 | -0.062688 |
| GPC3 | glypican 3 | -0.0626648 |
| RPS8 | ribosomal protein S8 | -0.0615898 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0584243 |
| CALR | calreticulin | -0.0583685 |
| PTMA | prothymosin, alpha | -0.0578391 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.057342 |
| RPS12 | ribosomal protein S12 | -0.0549638 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.054915 |
| UPP1 | uridine phosphorylase 1 | -0.0546634 |
| PGK1 | phosphoglycerate kinase 1 | -0.0536408 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0533995 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0508681 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0477387 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0475002 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0472586 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0471793 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0467781 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0467375 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0464345 |
| ACTG1 | actin gamma 1 | -0.0459504 |
| LPIN2 | lipin 2 | -0.0454465 |
| ENO1 | enolase 1, (alpha) | -0.0454433 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0452068 |
| MYO10 | myosin X | -0.043738 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0432136 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0431919 |
| ATXN2 | ataxin 2 | -0.0429382 |
| TNRC6B | trinucleotide repeat containing 6B | -0.042743 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0426865 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0402733 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0400853 |
| NEBL | nebulette | -0.0398264 |
| RPS3 | ribosomal protein S3 | -0.0396592 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0389996 |
| RPS6 | ribosomal protein S6 | -0.0389791 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0388465 |
| RPLP1 | ribosomal protein, large, P1 | -0.0387211 |
| PLPP1 | phospholipid phosphatase 1 | -0.0385465 |
| MYL12B | myosin, light chain 12B, regulatory | -0.038503 |
| APOE | apolipoprotein E | -0.0374461 |
| GSE1 | Gse1 coiled-coil protein | -0.0374076 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0369312 |
| MEIS2 | Meis homeobox 2 | -0.0365606 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0363848 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0359098 |
| ITGAV | integrin, alpha V | -0.035909 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0357869 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354163 |
| RPS27A | ribosomal protein S27a | -0.0340733 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0339899 |
| LRRC4C | leucine rich repeat containing 4C | -0.0339079 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0330753 |
| RPS13 | ribosomal protein S13 | -0.0330657 |
| ANK2 | ankyrin 2, neuronal | -0.0325697 |
| B2M | beta-2-microglobulin | -0.0322379 |
| HDAC9 | histone deacetylase 9 | -0.0321112 |
| FST | follistatin | -0.0320002 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.031146 |
| RPS19 | ribosomal protein S19 | -0.0310768 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0310264 |
| RPL35A | ribosomal protein L35a | -0.030749 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0306801 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0306083 |
| TUBA1B | tubulin, alpha 1b | -0.0304324 |
| TUT4 | terminal uridylyl transferase 4 | -0.0286909 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0286616 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0285855 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0284617 |
| TENM2 | teneurin transmembrane protein 2 | -0.0281691 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0281562 |
| PCDH11Y | protocadherin 11 Y-linked | -0.0280721 |
| RPL36A | ribosomal protein L36a | -0.0279374 |
| PRELID2 | PRELI domain containing 2 | -0.0271862 |
| NXN | nucleoredoxin | -0.0270243 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0265111 |
| RPLP0 | ribosomal protein, large, P0 | -0.0264191 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0262615 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0262376 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.026099 |
| RPL37 | ribosomal protein L37 | -0.0260413 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259669 |
| RPS23 | ribosomal protein S23 | -0.0257312 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0257292 |
| RAI1 | retinoic acid induced 1 | -0.0256711 |
| RPL23 | ribosomal protein L23 | -0.0256513 |
| RPL26 | ribosomal protein L26 | -0.0256475 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0256265 |
