| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.151573 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.149432 |
| NAV3 | neuron navigator 3 | 0.136122 |
| HDAC9 | histone deacetylase 9 | 0.130052 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106393 |
| SET | SET nuclear proto-oncogene | 0.0988568 |
| ZNF438 | zinc finger protein 438 | 0.0985406 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.097946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0966411 |
| FRMD4A | FERM domain containing 4A | 0.0885805 |
| FRMD6 | FERM domain containing 6 | 0.0816242 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0774257 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0758694 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0701922 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.065334 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0652801 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0623062 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0614884 |
| NABP1 | nucleic acid binding protein 1 | 0.059737 |
| CANX | calnexin | 0.0578501 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.0574285 |
| RPS6 | ribosomal protein S6 | 0.0565761 |
| RPS2 | ribosomal protein S2 | 0.0542211 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0537893 |
| POTEF | POTE ankyrin domain family, member F | 0.0529369 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0514372 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.05024 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0486738 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0480054 |
| RPS12 | ribosomal protein S12 | 0.0479286 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0479174 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0476456 |
| GOLGA4 | golgin A4 | 0.0460612 |
| JMJD1C | jumonji domain containing 1C | 0.0441048 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0431139 |
| TPM4 | tropomyosin 4 | 0.0426484 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0403585 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0399299 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0396572 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0384979 |
| ENO1 | enolase 1, (alpha) | 0.0384473 |
| ASPH | aspartate beta-hydroxylase | 0.0374131 |
| CUX1 | cut-like homeobox 1 | 0.0374096 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0371536 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0361997 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0345273 |
| PGK1 | phosphoglycerate kinase 1 | 0.0344652 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0336796 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0336299 |
| TPM3 | tropomyosin 3 | 0.0333719 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0323948 |
| RPL3 | ribosomal protein L3 | 0.0322257 |
| LAMB3 | laminin, beta 3 | 0.0318583 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0316496 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0312505 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0310847 |
| BPTF | bromodomain PHD finger transcription factor | 0.0309766 |
| SETX | senataxin | 0.0305467 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.030169 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0294921 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0293191 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291444 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0291298 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0288545 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0287697 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0287626 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0284394 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0282422 |
| INTS6 | integrator complex subunit 6 | 0.0281927 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0279223 |
| TTR | transthyretin | 0.0277113 |
| MORF4L2 | mortality factor 4 like 2 | 0.0267307 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0263356 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0262338 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0260381 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0258449 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0258007 |
| GOLGB1 | golgin B1 | 0.0256141 |
| DGKI | diacylglycerol kinase, iota | 0.0254188 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0253812 |
| FLNB | filamin B, beta | 0.0252218 |
| VMP1 | vacuole membrane protein 1 | 0.0251311 |
| MCL1 | myeloid cell leukemia 1 | 0.0247107 |
| BNC2 | basonuclin 2 | 0.0246165 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0244477 |
| NRDC | nardilysin convertase | 0.0243133 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0241956 |
| PRKCE | protein kinase C, epsilon | 0.0241328 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0240949 |
| HMGA2 | high mobility group AT-hook 2 | 0.0239682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0239596 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0239504 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0234083 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0232856 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0229236 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0228824 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0227795 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0227744 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0227329 |
| HM13 | histocompatibility (minor) 13 | 0.0227057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.135344 |
| ACTG1 | actin gamma 1 | -0.127682 |
| MT2A | metallothionein 2A | -0.0911683 |
| RPS21 | ribosomal protein S21 | -0.0712266 |
| RPL8 | ribosomal protein L8 | -0.0656062 |
| TMSB10 | thymosin beta 10 | -0.0552117 |
| RPLP2 | ribosomal protein, large, P2 | -0.0511441 |
| RPL35A | ribosomal protein L35a | -0.0475127 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0451261 |
| RPL32 | ribosomal protein L32 | -0.0446604 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0392779 |
| RPL34 | ribosomal protein L34 | -0.0384363 |
| RPLP1 | ribosomal protein, large, P1 | -0.0380789 |
| S100A2 | S100 calcium binding protein A2 | -0.037789 |
| HMGA1 | high mobility group AT-hook 1 | -0.0370081 |
| RPL36 | ribosomal protein L36 | -0.0361905 |
| RPL19 | ribosomal protein L19 | -0.0360235 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0355518 |
| USP3 | ubiquitin specific peptidase 3 | -0.0347173 |
| RPL12 | ribosomal protein L12 | -0.0345802 |
| SBF2 | SET binding factor 2 | -0.0328007 |
| RPLP0 | ribosomal protein, large, P0 | -0.0318644 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0312682 |
| RPS4X | ribosomal protein S4, X-linked | -0.0307758 |
| RPL13A | ribosomal protein L13a | -0.0299636 |
| RPL7A | ribosomal protein L7a | -0.0297759 |
| RPL23 | ribosomal protein L23 | -0.0296213 |
| RPS19 | ribosomal protein S19 | -0.0288836 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.028662 |
| HLA-C | major histocompatibility complex, class I, C | -0.0284476 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.028341 |
| RPL38 | ribosomal protein L38 | -0.0277222 |
| RPS23 | ribosomal protein S23 | -0.027577 |
| RPS24 | ribosomal protein S24 | -0.0269861 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0268858 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0264199 |
| RPL28 | ribosomal protein L28 | -0.0256953 |
| LOC112694756 | uncharaterized LOC112694756 | -0.025197 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0250503 |
| RPS11 | ribosomal protein S11 | -0.0247736 |
| RPS16 | ribosomal protein S16 | -0.0247311 |
| PHIP | pleckstrin homology domain interacting protein | -0.0237405 |
| PFN1 | profilin 1 | -0.0234653 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0233291 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0228429 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0227142 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0220005 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0213598 |
| RBM39 | RNA binding motif protein 39 | -0.0209559 |
| RPL36A | ribosomal protein L36a | -0.0208925 |
| OLA1 | Obg-like ATPase 1 | -0.0202913 |
| S100A9 | S100 calcium binding protein A9 | -0.0201202 |
| RPS15 | ribosomal protein S15 | -0.0200403 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0199195 |
| RPS29 | ribosomal protein S29 | -0.0199156 |
| RPL35 | ribosomal protein L35 | -0.0198701 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0194606 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0194419 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0193872 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.019221 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0192146 |
| RPS25 | ribosomal protein S25 | -0.0190999 |
| OGA | O-GlcNAcase | -0.0186824 |
| RPL27A | ribosomal protein L27a | -0.0184909 |
| MT1X | metallothionein 1X | -0.0183312 |
| CDK17 | cyclin-dependent kinase 17 | -0.0183035 |
| FHIT | fragile histidine triad | -0.0179336 |
| CD68 | CD68 molecule | -0.0179171 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0177847 |
| ATP13A3 | ATPase type 13A3 | -0.0172372 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0171473 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0170837 |
| HLA-B | major histocompatibility complex, class I, B | -0.0169179 |
| RPL23A | ribosomal protein L23a | -0.0168679 |
| RPS13 | ribosomal protein S13 | -0.016858 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0167302 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0165319 |
| RPS5 | ribosomal protein S5 | -0.0164621 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0161678 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0160978 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0160155 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0158885 |
| CAPRIN2 | caprin family member 2 | -0.0158602 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0155917 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0155819 |
| G0S2 | G0/G1 switch 2 | -0.0153667 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0153508 |
| TPI1 | triosephosphate isomerase 1 | -0.0153209 |
| RPL36AL | ribosomal protein L36a-like | -0.0149446 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.014645 |
| COPS2 | COP9 signalosome subunit 2 | -0.0146261 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor | -0.0145731 |
| HSF1 | heat shock transcription factor 1 | -0.0145301 |
| XPO7 | exportin 7 | -0.0144856 |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide | -0.0144679 |
| KIF20B | kinesin family member 20B | -0.0144466 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0143463 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0143278 |
| MTF2 | metal response element binding transcription factor 2 | -0.0142839 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0142664 |
