| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0697055 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0624209 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0493132 |
| ZNF292 | zinc finger protein 292 | 0.0464172 |
| GOLGA4 | golgin A4 | 0.0449915 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0408037 |
| RBM39 | RNA binding motif protein 39 | 0.0385058 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.037271 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0356805 |
| TFG | TRK-fused gene | 0.0347633 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0345709 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0319248 |
| QKI | QKI, KH domain containing, RNA binding | 0.0292126 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0289098 |
| RNF145 | ring finger protein 145 | 0.0272234 |
| TXNIP | thioredoxin interacting protein | 0.0254038 |
| NBAS | neuroblastoma amplified sequence | 0.025062 |
| RLF | rearranged L-myc fusion | 0.0246921 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0243313 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0238051 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.022593 |
| CCNL1 | cyclin L1 | 0.0223274 |
| VMP1 | vacuole membrane protein 1 | 0.0219768 |
| SRP54 | signal recognition particle 54kDa | 0.0218334 |
| NUP58 | nucleoporin 58 | 0.0218047 |
| TPR | translocated promoter region, nuclear basket protein | 0.0211042 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0210854 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0210578 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0210042 |
| RTN4 | reticulon 4 | 0.0209689 |
| COG5 | component of oligomeric golgi complex 5 | 0.0209214 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0205896 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0205218 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0202805 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0199392 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0197605 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0197079 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0192733 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0191658 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.019105 |
| CDC73 | cell division cycle 73 | 0.0188804 |
| USP3 | ubiquitin specific peptidase 3 | 0.0188553 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0186126 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0185415 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0181534 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0180173 |
| FBXO11 | F-box protein 11 | 0.0178316 |
| MORF4L2 | mortality factor 4 like 2 | 0.0177934 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0177468 |
| FAM13A | family with sequence similarity 13, member A | 0.0177236 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0174659 |
| NCKAP1 | NCK-associated protein 1 | 0.0173797 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0173348 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0172873 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0172322 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.017194 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0171516 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0170306 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0168979 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0168245 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0167125 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0162764 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0159719 |
| NEK7 | NIMA-related kinase 7 | 0.0158607 |
| PTK2 | protein tyrosine kinase 2 | 0.015778 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0157007 |
| CASC3 | cancer susceptibility candidate 3 | 0.0155642 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0155641 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0154584 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0153975 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0153458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0153411 |
| TMF1 | TATA element modulatory factor 1 | 0.0152088 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.015173 |
| SLMAP | sarcolemma associated protein | 0.015109 |
| DENND4A | DENN/MADD domain containing 4A | 0.0151014 |
| TBK1 | TANK-binding kinase 1 | 0.0148291 |
| SPAG9 | sperm associated antigen 9 | 0.0148031 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0147757 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.014715 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.014652 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0144116 |
| RAB18 | RAB18, member RAS oncogene family | 0.014362 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0143497 |
| SFXN1 | sideroflexin 1 | 0.0142811 |
| ATOSA | atos homolog A | 0.0142733 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0141429 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0140879 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0140722 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0140699 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0140449 |
| HELZ | helicase with zinc finger | 0.0140223 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0139369 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0138762 |
| KLHL24 | kelch-like family member 24 | 0.0138674 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0137948 |
| OGA | O-GlcNAcase | 0.0137947 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0137082 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0137021 |
| XPO1 | exportin 1 | 0.0136733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.233095 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.218537 |
| VCL | vinculin | -0.194431 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.19434 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.161146 |
| PTMA | prothymosin, alpha | -0.146021 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.140136 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.131269 |
| FOXP1 | forkhead box P1 | -0.109461 |
| BMP10 | bone morphogenetic protein 10 | -0.10505 |
| EGFR | epidermal growth factor receptor | -0.103933 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.101587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0987548 |
| NBEA | neurobeachin | -0.0882637 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0718075 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0677376 |
| CCND1 | cyclin D1 | -0.0674836 |
| AHNAK | AHNAK nucleoprotein | -0.067207 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0628425 |
| GLI3 | GLI family zinc finger 3 | -0.0613111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0605395 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.057922 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0569265 |
| ACTG1 | actin gamma 1 | -0.0568611 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0559013 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0557248 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0556073 |
| TJP1 | tight junction protein 1 | -0.055525 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0528335 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0527024 |
| GLI2 | GLI family zinc finger 2 | -0.0520684 |
| EFNA5 | ephrin-A5 | -0.0518073 |
| PKM | pyruvate kinase, muscle | -0.0506452 |
| RPS8 | ribosomal protein S8 | -0.050424 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0500741 |
| RPLP0 | ribosomal protein, large, P0 | -0.0491713 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0478407 |
| RPL34 | ribosomal protein L34 | -0.0476017 |
| RPL35A | ribosomal protein L35a | -0.0467818 |
| HDAC9 | histone deacetylase 9 | -0.0463786 |
| DUSP4 | dual specificity phosphatase 4 | -0.0444853 |
| MKI67 | marker of proliferation Ki-67 | -0.0441402 |
| RPL12 | ribosomal protein L12 | -0.042401 |
| RPS13 | ribosomal protein S13 | -0.0419425 |
| ENO1 | enolase 1, (alpha) | -0.0409943 |
| GSE1 | Gse1 coiled-coil protein | -0.040225 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0402044 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0400507 |
| RPS21 | ribosomal protein S21 | -0.0392082 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.039162 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0389619 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0382764 |
| RPS23 | ribosomal protein S23 | -0.0379941 |
| S100A4 | S100 calcium binding protein A4 | -0.0378051 |
| RPLP2 | ribosomal protein, large, P2 | -0.0375879 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0372282 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0372077 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0370945 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.037 |
| DIAPH3 | diaphanous-related formin 3 | -0.0367021 |
| MYO5C | myosin VC | -0.0365698 |
| RPL26 | ribosomal protein L26 | -0.0358847 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0356045 |
| CUX1 | cut-like homeobox 1 | -0.0355684 |
| RPS6 | ribosomal protein S6 | -0.0355459 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0348035 |
| RPLP1 | ribosomal protein, large, P1 | -0.0343067 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0337009 |
| RPL11 | ribosomal protein L11 | -0.0336274 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0331821 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0331549 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.033047 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0328592 |
| PDGFC | platelet derived growth factor C | -0.0326723 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.03258 |
| ZNF438 | zinc finger protein 438 | -0.0317205 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0316292 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0305511 |
| PYGB | phosphorylase, glycogen; brain | -0.0297722 |
| NFIA | nuclear factor I/A | -0.029739 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.029669 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0296465 |
| RPS24 | ribosomal protein S24 | -0.0294305 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.028656 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0286012 |
| RPL7A | ribosomal protein L7a | -0.0282352 |
| RPL19 | ribosomal protein L19 | -0.0281298 |
| FLNB | filamin B, beta | -0.0280792 |
| RPS25 | ribosomal protein S25 | -0.0277591 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0276088 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0275169 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0274745 |
| TPI1 | triosephosphate isomerase 1 | -0.0272592 |
| GPHN | gephyrin | -0.0270279 |
| S100A9 | S100 calcium binding protein A9 | -0.0265578 |
| RPL9 | ribosomal protein L9 | -0.0264896 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0259442 |
| FUS | FUS RNA binding protein | -0.0259101 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0256099 |
| PFN1 | profilin 1 | -0.0255601 |
