| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Berberine (chloride hydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.138347 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0970314 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0887666 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0827195 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0773618 |
| CADM1 | cell adhesion molecule 1 | 0.0771505 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.067697 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0663706 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0659203 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0655015 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0653398 |
| HDAC9 | histone deacetylase 9 | 0.0615601 |
| PDE10A | phosphodiesterase 10A | 0.0598743 |
| NAV2 | neuron navigator 2 | 0.059515 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0591547 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0554326 |
| MYOF | myoferlin | 0.0541838 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0537548 |
| FMNL2 | formin-like 2 | 0.0534373 |
| VEGFA | vascular endothelial growth factor A | 0.0533975 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0524684 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0523591 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0522832 |
| GOLGA4 | golgin A4 | 0.0499166 |
| DST | dystonin | 0.0492147 |
| HELZ | helicase with zinc finger | 0.0479854 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0474859 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0455098 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0447569 |
| CDH13 | cadherin 13 | 0.0443567 |
| FNIP1 | folliculin interacting protein 1 | 0.0441154 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0441028 |
| ASPH | aspartate beta-hydroxylase | 0.0440253 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0436967 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0435067 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0431391 |
| ZNF292 | zinc finger protein 292 | 0.0427344 |
| PRELID2 | PRELI domain containing 2 | 0.0425222 |
| PCBP2 | poly(rC) binding protein 2 | 0.0421319 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0419598 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.041281 |
| MMP12 | matrix metallopeptidase 12 | 0.0410793 |
| INTS6 | integrator complex subunit 6 | 0.0404362 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0404185 |
| NDRG1 | N-myc downstream regulated 1 | 0.0394441 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0394201 |
| CANX | calnexin | 0.0389402 |
| HMGA2 | high mobility group AT-hook 2 | 0.0389302 |
| PLIN2 | perilipin 2 | 0.0382025 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0378946 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0371758 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0365772 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0357841 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0354799 |
| ATP13A3 | ATPase type 13A3 | 0.0351618 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0350574 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0349742 |
| MSN | moesin | 0.0348864 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0345077 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0343684 |
| CCNL1 | cyclin L1 | 0.0339331 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0338727 |
| MYO1B | myosin IB | 0.0334129 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0333949 |
| PHF21A | PHD finger protein 21A | 0.0330187 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0329618 |
| FBXO32 | F-box protein 32 | 0.0324147 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0322534 |
| OPTN | optineurin | 0.0322528 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0321832 |
| JMJD1C | jumonji domain containing 1C | 0.0320886 |
| EGFR | epidermal growth factor receptor | 0.0315781 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0311797 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0307794 |
| CDK19 | cyclin-dependent kinase 19 | 0.0305313 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0304246 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0303957 |
| STAG2 | stromal antigen 2 | 0.0301724 |
| FAM13A | family with sequence similarity 13, member A | 0.0299008 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0298204 |
| ATXN1 | ataxin 1 | 0.0294884 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0294432 |
| MED13L | mediator complex subunit 13-like | 0.0294371 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0286763 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0282854 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0282464 |
| PHF3 | PHD finger protein 3 | 0.0282154 |
| BBX | bobby sox homolog (Drosophila) | 0.0279445 |
| TMEM132D | transmembrane protein 132D | 0.0278662 |
| SPAG9 | sperm associated antigen 9 | 0.0278102 |
| MORF4L2 | mortality factor 4 like 2 | 0.0276238 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0276207 |
| EFNA5 | ephrin-A5 | 0.0275831 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.027482 |
| ZNF638 | zinc finger protein 638 | 0.0274767 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0274289 |
| CD109 | CD109 molecule | 0.0272687 |
| RYBP | RING1 and YY1 binding protein | 0.0271553 |
| KIF13A | kinesin family member 13A | 0.0271413 |
| SETD5 | SET domain containing 5 | 0.0271147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.159653 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.144759 |
| VIM | vimentin | -0.140374 |
| VCL | vinculin | -0.125037 |
| HLA-B | major histocompatibility complex, class I, B | -0.110757 |
| TMSB10 | thymosin beta 10 | -0.0886476 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.081616 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0803883 |
| BICC1 | BicC family RNA binding protein 1 | -0.076546 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0739294 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0710392 |
| CD44 | CD44 molecule (Indian blood group) | -0.0562361 |
| OSMR | oncostatin M receptor | -0.0520926 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0501315 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0499842 |
| IER3 | immediate early response 3 | -0.0493491 |
| THBS1 | thrombospondin 1 | -0.0472642 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.046385 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458109 |
| MKI67 | marker of proliferation Ki-67 | -0.0444785 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0440757 |
| ANXA2 | annexin A2 | -0.0429479 |
| MT2A | metallothionein 2A | -0.0426041 |
| RIGI | RNA sensor RIG-I | -0.0420514 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0401919 |
| CDCP1 | CUB domain containing protein 1 | -0.039869 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0389614 |
| PALLD | palladin, cytoskeletal associated protein | -0.0375995 |
| FN1 | fibronectin 1 | -0.0375188 |
| RPL35A | ribosomal protein L35a | -0.0367737 |
| SMAD3 | SMAD family member 3 | -0.0360422 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0359912 |
| RPL23 | ribosomal protein L23 | -0.0356651 |
| KLF6 | Kruppel-like factor 6 | -0.0354432 |
| EGR1 | early growth response 1 | -0.0342785 |
| RPS24 | ribosomal protein S24 | -0.0336797 |
| RPL36A | ribosomal protein L36a | -0.0331412 |
| RPL26 | ribosomal protein L26 | -0.0325096 |
| HLA-E | major histocompatibility complex, class I, E | -0.0322359 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0321931 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0321193 |
| HLA-C | major histocompatibility complex, class I, C | -0.0320427 |
| THBS2 | thrombospondin 2 | -0.0314946 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0314535 |
| RTN4 | reticulon 4 | -0.0308457 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0308001 |
| ACTG1 | actin gamma 1 | -0.0306236 |
| GLIS3 | GLIS family zinc finger 3 | -0.0304313 |
| TUBB | tubulin, beta class I | -0.0300205 |
| CTSB | cathepsin B | -0.0296258 |
| RRBP1 | ribosome binding protein 1 | -0.0292116 |
| NABP1 | nucleic acid binding protein 1 | -0.0291813 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0290496 |
| HLA-A | major histocompatibility complex, class I, A | -0.0289426 |
| TPM4 | tropomyosin 4 | -0.0282796 |
| GNAS | GNAS complex locus | -0.0281411 |
| FTL | ferritin, light polypeptide | -0.0279412 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0277392 |
| TNNC1 | troponin C type 1 (slow) | -0.0275863 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274794 |
| ACTN1 | actinin, alpha 1 | -0.0272581 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0269502 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0263995 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260415 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0259874 |
| RPS21 | ribosomal protein S21 | -0.0244408 |
| CENPF | centromere protein F, 350/400kDa | -0.0237243 |
| DENND5A | DENN/MADD domain containing 5A | -0.0231308 |
| RPS3 | ribosomal protein S3 | -0.0230938 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0230028 |
| RPL36 | ribosomal protein L36 | -0.0229233 |
| WDR1 | WD repeat domain 1 | -0.0227391 |
| RPS19 | ribosomal protein S19 | -0.0226175 |
| KRT19 | keratin 19, type I | -0.0224601 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0224226 |
| RPL37A | ribosomal protein L37a | -0.0222751 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0222706 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0222279 |
| RPL12 | ribosomal protein L12 | -0.0221223 |
| RPL34 | ribosomal protein L34 | -0.0217888 |
| RPS4X | ribosomal protein S4, X-linked | -0.0216809 |
| KIF4A | kinesin family member 4A | -0.0215325 |
| LOXL2 | lysyl oxidase-like 2 | -0.021442 |
| PRR11 | proline rich 11 | -0.0213221 |
| RPL19 | ribosomal protein L19 | -0.0210836 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0209842 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.020983 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.020888 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0206943 |
| XAF1 | XIAP associated factor 1 | -0.0206782 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0205927 |
| RPL32 | ribosomal protein L32 | -0.0205758 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.020425 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0203544 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.020095 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0200511 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0200506 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0199049 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0198326 |
| CTSD | cathepsin D | -0.0197771 |
