| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Berberine (chloride hydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Berberine (chloride hydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.116801 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.111024 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0994896 |
| NAV2 | neuron navigator 2 | 0.0953629 |
| ASPH | aspartate beta-hydroxylase | 0.0878968 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0840468 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0682193 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0635246 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0603508 |
| AHNAK | AHNAK nucleoprotein | 0.0548684 |
| POTEF | POTE ankyrin domain family, member F | 0.0526255 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0521284 |
| CCND1 | cyclin D1 | 0.0490108 |
| RAD51B | RAD51 paralog B | 0.0474381 |
| PTMA | prothymosin, alpha | 0.046197 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0459773 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0458731 |
| CD44 | CD44 molecule (Indian blood group) | 0.0451831 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.043701 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0429176 |
| INTS6 | integrator complex subunit 6 | 0.0405649 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0404887 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0401635 |
| WWOX | WW domain containing oxidoreductase | 0.0363754 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0347926 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0325884 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0311185 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0308982 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0305132 |
| FHIT | fragile histidine triad | 0.029452 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0286438 |
| EGFR | epidermal growth factor receptor | 0.0275369 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0274456 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0272397 |
| RBP1 | retinol binding protein 1, cellular | 0.0270549 |
| EXOC4 | exocyst complex component 4 | 0.0264433 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.026335 |
| TPM3 | tropomyosin 3 | 0.0252555 |
| ENO1 | enolase 1, (alpha) | 0.0249645 |
| SET | SET nuclear proto-oncogene | 0.0248515 |
| LDHA | lactate dehydrogenase A | 0.0247189 |
| CADM1 | cell adhesion molecule 1 | 0.0244022 |
| PKM | pyruvate kinase, muscle | 0.0240523 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0235954 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0227601 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0226131 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0225852 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0223513 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0218268 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0216049 |
| CLSTN2 | calsyntenin 2 | 0.0215676 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0213369 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0213276 |
| SKAP1 | src kinase associated phosphoprotein 1 | 0.0207695 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.020704 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0206107 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0203507 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0201174 |
| ZNF704 | zinc finger protein 704 | 0.020081 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0193516 |
| MKI67 | marker of proliferation Ki-67 | 0.0191478 |
| IGF2 | insulin-like growth factor 2 | 0.0190356 |
| KIZ | kizuna centrosomal protein | 0.0189739 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0189583 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.018627 |
| CUX1 | cut-like homeobox 1 | 0.0185731 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0184572 |
| FNIP1 | folliculin interacting protein 1 | 0.0183413 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0182922 |
| GLI3 | GLI family zinc finger 3 | 0.0182358 |
| FOXN3 | forkhead box N3 | 0.0181681 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0180733 |
| DEK | DEK proto-oncogene | 0.0177758 |
| NPAS2 | neuronal PAS domain protein 2 | 0.017652 |
| EMP1 | epithelial membrane protein 1 | 0.0176218 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.017483 |
| IPO7 | importin 7 | 0.0174271 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0171319 |
| MYOF | myoferlin | 0.0167246 |
| PUS7 | pseudouridylate synthase 7 (putative) | 0.0167202 |
| FAT1 | FAT atypical cadherin 1 | 0.0167029 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A | 0.0166687 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0166361 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0165417 |
| AATF | apoptosis antagonizing transcription factor | 0.0162392 |
| HIP1 | huntingtin interacting protein 1 | 0.0159795 |
| MSN | moesin | 0.0158045 |
| CEP112 | centrosomal protein 112kDa | 0.0157725 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0157013 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0156772 |
| ANLN | anillin, actin binding protein | 0.0155637 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0154314 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0154247 |
| RPS8 | ribosomal protein S8 | 0.0152107 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0147082 |
| MYO10 | myosin X | 0.0146054 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.0145758 |
| PRELID2 | PRELI domain containing 2 | 0.0144582 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0143829 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0143134 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.141232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.124022 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0873897 |
| TMSB10 | thymosin beta 10 | -0.0767299 |
| SYT1 | synaptotagmin I | -0.0694826 |
| EGR1 | early growth response 1 | -0.0631572 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.063058 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0601871 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0586307 |
| RUNX1 | runt-related transcription factor 1 | -0.0583991 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0566748 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0525398 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0511854 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0502431 |
| BCL2L1 | BCL2-like 1 | -0.0501249 |
| RPS3 | ribosomal protein S3 | -0.0494488 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0488941 |
| ETNK1 | ethanolamine kinase 1 | -0.04771 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0461565 |
| LMO7 | LIM domain 7 | -0.0455545 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0446952 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0433943 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0433708 |
| NF1 | neurofibromin 1 | -0.0420284 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0403569 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0399415 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0389338 |
| THOC2 | THO complex 2 | -0.0386992 |
| PROX1 | prospero homeobox 1 | -0.0385456 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0378994 |
| RPS19 | ribosomal protein S19 | -0.0376536 |
| SPATA13 | spermatogenesis associated 13 | -0.0376228 |
| RBM39 | RNA binding motif protein 39 | -0.0374345 |
| JMJD1C | jumonji domain containing 1C | -0.037307 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0368613 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0364521 |
| KLF6 | Kruppel-like factor 6 | -0.036435 |
| ACTN4 | actinin, alpha 4 | -0.0359619 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0353371 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0348035 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0343661 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0335317 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | -0.0330968 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0325958 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0325563 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0324118 |
| CCDC82 | coiled-coil domain containing 82 | -0.0324063 |
| TMEM41B | transmembrane protein 41B | -0.0322402 |
| RACK1 | receptor for activated C kinase 1 | -0.0321044 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0318515 |
| ACTG1 | actin gamma 1 | -0.0318237 |
| ATXN1 | ataxin 1 | -0.0318069 |
| EFNB2 | ephrin-B2 | -0.0316033 |
| RPL18 | ribosomal protein L18 | -0.0311316 |
| OGA | O-GlcNAcase | -0.0308248 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304856 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0303276 |
| AOPEP | aminopeptidase O (putative) | -0.0301942 |
| RPL12 | ribosomal protein L12 | -0.029833 |
| CEP95 | centrosomal protein 95kDa | -0.0297742 |
| SETD5 | SET domain containing 5 | -0.0293352 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0292788 |
| ABHD2 | abhydrolase domain containing 2 | -0.0292749 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0292581 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0289374 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0284375 |
| FOXP1 | forkhead box P1 | -0.0283001 |
| TMEM123 | transmembrane protein 123 | -0.0273975 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0273296 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0273039 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0273019 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0272633 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0271258 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0270456 |
| NKTR | natural killer cell triggering receptor | -0.0269726 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0268943 |
| DUSP6 | dual specificity phosphatase 6 | -0.026742 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0267124 |
| GLG1 | golgi glycoprotein 1 | -0.0267023 |
| RPL32 | ribosomal protein L32 | -0.0264494 |
| RPS12 | ribosomal protein S12 | -0.0264298 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0263383 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0262833 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0260545 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0259535 |
| RPS4X | ribosomal protein S4, X-linked | -0.0256418 |
| RPL23 | ribosomal protein L23 | -0.0256066 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0255775 |
| SON | SON DNA binding protein | -0.0255376 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0253884 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0252784 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0251848 |
| UTRN | utrophin | -0.0250385 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0248523 |
| DST | dystonin | -0.0248085 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0247678 |
| ATF4 | activating transcription factor 4 | -0.0247425 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.024537 |
| VMP1 | vacuole membrane protein 1 | -0.0244347 |
| SH3D19 | SH3 domain containing 19 | -0.0240164 |
