| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMEM41B | transmembrane protein 41B | 0.0871758 |
| VIM | vimentin | 0.0730891 |
| RPS12 | ribosomal protein S12 | 0.0716082 |
| ACTG1 | actin gamma 1 | 0.0711525 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0706191 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.070158 |
| JMJD1C | jumonji domain containing 1C | 0.0567729 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0544416 |
| RPS2 | ribosomal protein S2 | 0.0526552 |
| RAB7A | RAB7A, member RAS oncogene family | 0.050957 |
| EHBP1 | EH domain binding protein 1 | 0.0506592 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0503299 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0497253 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0483298 |
| MTAP | methylthioadenosine phosphorylase | 0.0460551 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0459673 |
| HMGA2 | high mobility group AT-hook 2 | 0.0458466 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0437289 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0423539 |
| EDARADD | EDAR-associated death domain | 0.0404778 |
| ASPH | aspartate beta-hydroxylase | 0.0402566 |
| RPL26 | ribosomal protein L26 | 0.0393654 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.035483 |
| NHSL1 | NHS-like 1 | 0.0334455 |
| RRM2 | ribonucleotide reductase M2 | 0.0334207 |
| MYL12B | myosin, light chain 12B, regulatory | 0.032149 |
| RPL4 | ribosomal protein L4 | 0.0309003 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0302493 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0298045 |
| CAVIN1 | caveolae associated protein 1 | 0.0297094 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0290683 |
| RPL37A | ribosomal protein L37a | 0.028223 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0281039 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0280644 |
| XPOT | exportin, tRNA | 0.0280142 |
| RTN4 | reticulon 4 | 0.0279721 |
| NAV3 | neuron navigator 3 | 0.0279596 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0264937 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0263635 |
| RPL27 | ribosomal protein L27 | 0.0262933 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0255692 |
| BCHE | butyrylcholinesterase | 0.0255059 |
| RPS3 | ribosomal protein S3 | 0.025432 |
| PGK1 | phosphoglycerate kinase 1 | 0.0252006 |
| OSMR | oncostatin M receptor | 0.0251218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0245923 |
| PRDX1 | peroxiredoxin 1 | 0.023746 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0232254 |
| RPL37 | ribosomal protein L37 | 0.0228057 |
| ATF4 | activating transcription factor 4 | 0.0227427 |
| AREG | amphiregulin | 0.0222925 |
| ANK2 | ankyrin 2, neuronal | 0.0215013 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.0212984 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.0209135 |
| CUX1 | cut-like homeobox 1 | 0.020793 |
| PTMA | prothymosin, alpha | 0.0207199 |
| ENO1 | enolase 1, (alpha) | 0.0203624 |
| EZR | ezrin | 0.0200865 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0199682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0195364 |
| GCG | glucagon | 0.0187988 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.0185409 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0181368 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0180965 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0180653 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0180495 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0178097 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0177072 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0175778 |
| CENPF | centromere protein F, 350/400kDa | 0.0175651 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0173788 |
| FOSL1 | FOS-like antigen 1 | 0.0172704 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0170879 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0169805 |
| KLF6 | Kruppel-like factor 6 | 0.0169054 |
| RPS17 | ribosomal protein S17 | 0.0169003 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0167253 |
| TPM3 | tropomyosin 3 | 0.0166266 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0164871 |
| CANX | calnexin | 0.0162504 |
| RPS8 | ribosomal protein S8 | 0.0160687 |
| DUSP6 | dual specificity phosphatase 6 | 0.0157547 |
| RPL12 | ribosomal protein L12 | 0.0156434 |
| RPS7 | ribosomal protein S7 | 0.0155973 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) | 0.0154708 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0149788 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0149238 |
| OCIAD1 | OCIA domain containing 1 | 0.0147509 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0145861 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0145725 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.014524 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0144341 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0142655 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0142171 |
| SESN2 | sestrin 2 | 0.0141548 |
| NABP1 | nucleic acid binding protein 1 | 0.0141473 |
| RANBP17 | RAN binding protein 17 | 0.0141414 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0139913 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.013957 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.0139552 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109225 |
| TMSB10 | thymosin beta 10 | -0.0933804 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0932399 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0906386 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0890558 |
| TENM3 | teneurin transmembrane protein 3 | -0.0791391 |
| DST | dystonin | -0.0758991 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0750776 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0714491 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0713469 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0689507 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0660523 |
| SYT1 | synaptotagmin I | -0.0647239 |
| PFN1 | profilin 1 | -0.0643325 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.062227 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0605603 |
| YBX1 | Y box binding protein 1 | -0.0602523 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0597418 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0579347 |
| PCBP2 | poly(rC) binding protein 2 | -0.0575724 |
| PTMS | parathymosin | -0.0561593 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0561162 |
| CPOX | coproporphyrinogen oxidase | -0.0538456 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0528042 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0526599 |
| NF1 | neurofibromin 1 | -0.0525167 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0523934 |
| HMGA1 | high mobility group AT-hook 1 | -0.0517883 |
| MED13L | mediator complex subunit 13-like | -0.0511362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0503538 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0496606 |
| POTEF | POTE ankyrin domain family, member F | -0.0490172 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0484619 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0469195 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0459311 |
| ECT2 | epithelial cell transforming 2 | -0.0447714 |
| PRRC2C | proline-rich coiled-coil 2C | -0.044729 |
| XPO1 | exportin 1 | -0.0443591 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0442156 |
| FBXO11 | F-box protein 11 | -0.0438814 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0428941 |
| LDHB | lactate dehydrogenase B | -0.0426783 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0423297 |
| CDK6 | cyclin-dependent kinase 6 | -0.0422061 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.042047 |
| BPTF | bromodomain PHD finger transcription factor | -0.04139 |
| MGAT4C | MGAT4 family, member C | -0.0403214 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0401428 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0399775 |
| ZNF207 | zinc finger protein 207 | -0.0391294 |
| NLGN1 | neuroligin 1 | -0.0390785 |
| MATR3 | matrin 3 | -0.0388533 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.038812 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0386153 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0384769 |
| EDN1 | endothelin 1 | -0.0382065 |
| CCDC88A | coiled-coil domain containing 88A | -0.0376543 |
| CCNL1 | cyclin L1 | -0.0374844 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0373652 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0372697 |
| EPHA6 | EPH receptor A6 | -0.0362191 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0358899 |
| USP34 | ubiquitin specific peptidase 34 | -0.0358818 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0356442 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0353025 |
| RPS6 | ribosomal protein S6 | -0.0349182 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0347651 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0347498 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0347135 |
| SETD5 | SET domain containing 5 | -0.0344692 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0343053 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0337396 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0336088 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0335489 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0335193 |
| RPS19 | ribosomal protein S19 | -0.0333312 |
| PRKCI | protein kinase C, iota | -0.0329369 |
| TMEM131 | transmembrane protein 131 | -0.032503 |
| MED13 | mediator complex subunit 13 | -0.0324838 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0324336 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0321345 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0320957 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0319361 |
| SPAG9 | sperm associated antigen 9 | -0.0318513 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0317409 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0313231 |
| TBK1 | TANK-binding kinase 1 | -0.0312665 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0312655 |
| KLHL24 | kelch-like family member 24 | -0.0311931 |
| SEPTIN7 | septin 7 | -0.0311467 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0310782 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0309203 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0306676 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0306226 |
| CBX3 | chromobox homolog 3 | -0.0306047 |
| POU2F1 | POU class 2 homeobox 1 | -0.0304907 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0301724 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0301566 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0300174 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0299574 |
