| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Bergenin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.224026 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.12771 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0904073 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0705518 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0646083 |
| MYO1E | myosin IE | 0.0628894 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0625947 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0614755 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0613853 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0598976 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0580659 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0549544 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0542871 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0532563 |
| TOX3 | TOX high mobility group box family member 3 | 0.0523885 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0483037 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0478547 |
| SMAD3 | SMAD family member 3 | 0.0467302 |
| TMC5 | transmembrane channel-like 5 | 0.0430741 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0398554 |
| ASPH | aspartate beta-hydroxylase | 0.0383144 |
| UBC | ubiquitin C | 0.0380992 |
| EZR | ezrin | 0.0367506 |
| MLPH | melanophilin | 0.0362174 |
| ANXA2 | annexin A2 | 0.0359418 |
| FHL2 | four and a half LIM domains 2 | 0.0346831 |
| DPP4 | dipeptidyl-peptidase 4 | 0.032035 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0317109 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0315427 |
| PRSS3 | protease, serine, 3 | 0.0313737 |
| AREG | amphiregulin | 0.0311385 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0304677 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0304501 |
| PDZD8 | PDZ domain containing 8 | 0.0301034 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0293367 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0285784 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0284262 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0283172 |
| PTMA | prothymosin, alpha | 0.0274582 |
| DST | dystonin | 0.0274219 |
| KYNU | kynureninase | 0.0273831 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0270584 |
| DUSP10 | dual specificity phosphatase 10 | 0.0269798 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0266302 |
| EREG | epiregulin | 0.0263601 |
| TUT7 | terminal uridylyl transferase 7 | 0.0260233 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0248549 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0244922 |
| EFNB2 | ephrin-B2 | 0.0241952 |
| YAP1 | Yes-associated protein 1 | 0.0241073 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0240474 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.023572 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0230616 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0224761 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0223134 |
| PCBP2 | poly(rC) binding protein 2 | 0.0222573 |
| BCL2L1 | BCL2-like 1 | 0.0221142 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0220713 |
| FNIP2 | folliculin interacting protein 2 | 0.0219029 |
| RPL7L1 | ribosomal protein L7-like 1 | 0.0218798 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0217661 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0216686 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.021637 |
| SLK | STE20-like kinase | 0.021339 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0211183 |
| TMEM65 | transmembrane protein 65 | 0.0209632 |
| FTL | ferritin, light polypeptide | 0.0208225 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0203686 |
| TRIB1 | tribbles pseudokinase 1 | 0.0199575 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0198157 |
| RND3 | Rho family GTPase 3 | 0.0198131 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.019721 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0194346 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0191667 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0190826 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0190032 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0189629 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.018784 |
| SLTM | SAFB-like, transcription modulator | 0.0187719 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0186712 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0183374 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0181699 |
| USP54 | ubiquitin specific peptidase 54 | 0.0180183 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.0177359 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0176684 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0176594 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0172758 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0172209 |
| MYO5B | myosin VB | 0.0172005 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0169901 |
| CSTB | cystatin B (stefin B) | 0.0169585 |
| LIMA1 | LIM domain and actin binding 1 | 0.0168559 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0168447 |
| CAPN8 | calpain 8 | 0.0167458 |
| MYOF | myoferlin | 0.0167319 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0167142 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0164384 |
| CTBP2 | C-terminal binding protein 2 | 0.0164205 |
| LAMB3 | laminin, beta 3 | 0.0161113 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0160786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.172525 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.143864 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.122791 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.122474 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.117048 |
| MX1 | MX dynamin-like GTPase 1 | -0.110571 |
| RIGI | RNA sensor RIG-I | -0.0896555 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0878244 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0846629 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0823115 |
| PRKCA | protein kinase C, alpha | -0.075481 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0740261 |
| RNF213 | ring finger protein 213 | -0.0656216 |
| RAD51B | RAD51 paralog B | -0.063964 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0620299 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.061616 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0614024 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0605367 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0591225 |
| PLSCR1 | phospholipid scramblase 1 | -0.0588125 |
| NPSR1 | neuropeptide S receptor 1 | -0.0571866 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0514383 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0506274 |
| EPHB2 | EPH receptor B2 | -0.0497987 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0486309 |
| PLSCR2 | phospholipid scramblase 2 | -0.0482038 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.046113 |
| FOXP1 | forkhead box P1 | -0.0455488 |
| XAF1 | XIAP associated factor 1 | -0.0452754 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0450867 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0450199 |
| IRF1 | interferon regulatory factor 1 | -0.0447017 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0442569 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0430036 |
| SP100 | SP100 nuclear antigen | -0.0425895 |
| TXNIP | thioredoxin interacting protein | -0.042491 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0421602 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0420832 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.041581 |
| PKM | pyruvate kinase, muscle | -0.040577 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0404525 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0398748 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394335 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0392886 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0390013 |
| EGR1 | early growth response 1 | -0.0389933 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0385722 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0385451 |
| NDRG1 | N-myc downstream regulated 1 | -0.0378151 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0373158 |
| SSH2 | slingshot protein phosphatase 2 | -0.0367049 |
| DIAPH3 | diaphanous-related formin 3 | -0.0366449 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0365932 |
| TRIM25 | tripartite motif containing 25 | -0.0361838 |
| PHF3 | PHD finger protein 3 | -0.035821 |
| RUNX1 | runt-related transcription factor 1 | -0.0355304 |
| SPATA13 | spermatogenesis associated 13 | -0.0351473 |
| PRELID2 | PRELI domain containing 2 | -0.0334734 |
| VEGFA | vascular endothelial growth factor A | -0.0332173 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0329548 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.032585 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0323302 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0322959 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0317639 |
| PMP22 | peripheral myelin protein 22 | -0.0315884 |
| LYZ | lysozyme | -0.0315379 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0315182 |
| VCL | vinculin | -0.0313124 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0310978 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0304383 |
| MECOM | MDS1 and EVI1 complex locus | -0.0302423 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0296469 |
| CTSD | cathepsin D | -0.029128 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0287957 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0283521 |
| SQSTM1 | sequestosome 1 | -0.0281817 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0281673 |
| CLYBL | citrate lyase beta like | -0.0279438 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0278261 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027286 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.027248 |
| MSI2 | musashi RNA-binding protein 2 | -0.0272385 |
| ZNF207 | zinc finger protein 207 | -0.026859 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.026276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0260908 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0260318 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0258615 |
| CCNL1 | cyclin L1 | -0.025779 |
| MED13L | mediator complex subunit 13-like | -0.025732 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0256891 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0255269 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.02548 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0253169 |
| GRM8 | glutamate receptor, metabotropic 8 | -0.0252306 |
| SERINC5 | serine incorporator 5 | -0.0251467 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0251143 |
| PTEN | phosphatase and tensin homolog | -0.0250786 |
| PHF14 | PHD finger protein 14 | -0.0249926 |
| SETX | senataxin | -0.0249529 |
| COMMD10 | COMM domain containing 10 | -0.0248468 |
