| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.341317 |
| MT2A | metallothionein 2A | 0.110871 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.105857 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.102142 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0882503 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0799923 |
| CD44 | CD44 molecule (Indian blood group) | 0.0667117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0606717 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0586978 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0557444 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0534995 |
| STC1 | stanniocalcin 1 | 0.052265 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0476814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0427372 |
| ARRDC3 | arrestin domain containing 3 | 0.0424724 |
| MSN | moesin | 0.0360467 |
| ANXA2 | annexin A2 | 0.0360092 |
| SMAD3 | SMAD family member 3 | 0.0359923 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0346711 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.034414 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.034223 |
| RPL3 | ribosomal protein L3 | 0.0291875 |
| MLF1 | myeloid leukemia factor 1 | 0.0285776 |
| ENO1 | enolase 1, (alpha) | 0.0278495 |
| FOSL1 | FOS-like antigen 1 | 0.0263662 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0255483 |
| NOTCH2 | notch 2 | 0.0248349 |
| RPS2 | ribosomal protein S2 | 0.024721 |
| EFNA5 | ephrin-A5 | 0.0244424 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.024272 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.023174 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.023075 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0223921 |
| FAM13A | family with sequence similarity 13, member A | 0.0221169 |
| TPM3 | tropomyosin 3 | 0.021619 |
| PDE10A | phosphodiesterase 10A | 0.021026 |
| RUNX1 | runt-related transcription factor 1 | 0.0201872 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0199048 |
| PFKP | phosphofructokinase, platelet | 0.0198826 |
| HLA-A | major histocompatibility complex, class I, A | 0.0197408 |
| HSPA8 | heat shock 70kDa protein 8 | 0.01944 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0192407 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0191996 |
| DUSP6 | dual specificity phosphatase 6 | 0.0190624 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0190092 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0189883 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0179011 |
| NAV2 | neuron navigator 2 | 0.0178739 |
| H1-0 | H1.0 linker histone | 0.0177224 |
| H1-4 | H1.4 linker histone, cluster member | 0.0176528 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0175133 |
| MYO9B | myosin IXB | 0.017339 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0170378 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0170057 |
| TMEM165 | transmembrane protein 165 | 0.016877 |
| SYAP1 | synapse associated protein 1 | 0.016701 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0166604 |
| DCP1A | decapping mRNA 1A | 0.0164798 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0162466 |
| SUCO | SUN domain containing ossification factor | 0.0162331 |
| ARSJ | arylsulfatase family, member J | 0.0160022 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0159948 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0158713 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0158187 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0157337 |
| ATP13A3 | ATPase type 13A3 | 0.0156179 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0152256 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0150778 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0149762 |
| RPL4 | ribosomal protein L4 | 0.0148926 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0147133 |
| TMF1 | TATA element modulatory factor 1 | 0.0144859 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0143239 |
| VEGFC | vascular endothelial growth factor C | 0.0141497 |
| ANGPTL4 | angiopoietin-like 4 | 0.0141164 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0141153 |
| FSTL1 | follistatin-like 1 | 0.0140362 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0139822 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0138657 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0137582 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0137265 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0134875 |
| RND3 | Rho family GTPase 3 | 0.0134027 |
| CA12 | carbonic anhydrase XII | 0.0133632 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0133557 |
| ZNF706 | zinc finger protein 706 | 0.0132387 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0131485 |
| SEPTIN9 | septin 9 | 0.0131175 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 0.0131063 |
| MTSS1 | metastasis suppressor 1 | 0.0130905 |
| FYTTD1 | forty-two-three domain containing 1 | 0.0130642 |
| PCBP2 | poly(rC) binding protein 2 | 0.0129427 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0129274 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0127761 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0124734 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0122126 |
| OPTN | optineurin | 0.0122002 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0121567 |
| SLMAP | sarcolemma associated protein | 0.0121285 |
| TRAM2 | translocation associated membrane protein 2 | 0.0120834 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.230228 |
| COL1A2 | collagen, type I, alpha 2 | -0.173763 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.166211 |
| TMSB10 | thymosin beta 10 | -0.141806 |
| VIM | vimentin | -0.117501 |
| CADM1 | cell adhesion molecule 1 | -0.115473 |
| IER3 | immediate early response 3 | -0.104453 |
| CDH13 | cadherin 13 | -0.0981184 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0953157 |
| RPL35A | ribosomal protein L35a | -0.0842156 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0833483 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0809128 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0764943 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0742671 |
| COL5A1 | collagen, type V, alpha 1 | -0.0691468 |
| FBN1 | fibrillin 1 | -0.0635674 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0604727 |
| NDRG1 | N-myc downstream regulated 1 | -0.0587828 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0578003 |
| TPM4 | tropomyosin 4 | -0.0570905 |
| CALD1 | caldesmon 1 | -0.0551587 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0548168 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0512386 |
| PTMA | prothymosin, alpha | -0.0508546 |
| CALR | calreticulin | -0.0506217 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0502251 |
| RPS8 | ribosomal protein S8 | -0.0493242 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0491309 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0476114 |
| FTL | ferritin, light polypeptide | -0.0472503 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0453984 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0449636 |
| HLA-B | major histocompatibility complex, class I, B | -0.0436433 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0434779 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0424913 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0422309 |
| VCL | vinculin | -0.041726 |
| CAVIN1 | caveolae associated protein 1 | -0.041483 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.040921 |
| GLIS3 | GLIS family zinc finger 3 | -0.0397414 |
| RRBP1 | ribosome binding protein 1 | -0.0382859 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0382673 |
| S100A9 | S100 calcium binding protein A9 | -0.0381444 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0364656 |
| RPL11 | ribosomal protein L11 | -0.0355088 |
| RPL23 | ribosomal protein L23 | -0.0351839 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0350912 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0347443 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0343743 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0343413 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0341708 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0334921 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0329153 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0325533 |
| STC2 | stanniocalcin 2 | -0.0317766 |
| S100A6 | S100 calcium binding protein A6 | -0.0316062 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0315033 |
| RPS6 | ribosomal protein S6 | -0.0310725 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0309075 |
| MTDH | metadherin | -0.0305519 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0305239 |
| RPS24 | ribosomal protein S24 | -0.0304807 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0303213 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0303163 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0301332 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0300976 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0300038 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0292389 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0290994 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0289695 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0287729 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0284652 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0284491 |
| FN1 | fibronectin 1 | -0.0279407 |
| TENM3 | teneurin transmembrane protein 3 | -0.0278731 |
| TPM1 | tropomyosin 1 (alpha) | -0.027721 |
| GOLGB1 | golgin B1 | -0.0276902 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0275886 |
| TNRC6B | trinucleotide repeat containing 6B | -0.027484 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0273738 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0273402 |
| CLMP | CXADR-like membrane protein | -0.0272984 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0272278 |
| PALLD | palladin, cytoskeletal associated protein | -0.0271223 |
| TMSB4X | thymosin beta 4, X-linked | -0.0271186 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0271047 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0270625 |
| NEK10 | NIMA-related kinase 10 | -0.0270588 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0264593 |
| INHBA | inhibin, beta A | -0.026316 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0258511 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0258118 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0256543 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0255477 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0253778 |
| COL3A1 | collagen, type III, alpha 1 | -0.0252643 |
| ACTG1 | actin gamma 1 | -0.0251092 |
| LAMB3 | laminin, beta 3 | -0.0250039 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0249141 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0248025 |
