| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.184673 |
| TGM2 | transglutaminase 2 | 0.0950659 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0766104 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0737889 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0724299 |
| RAI14 | retinoic acid induced 14 | 0.0700541 |
| LMO7 | LIM domain 7 | 0.0605304 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0532825 |
| MTSS1 | metastasis suppressor 1 | 0.0530721 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0523444 |
| PODXL | podocalyxin-like | 0.051971 |
| EFNA5 | ephrin-A5 | 0.0482225 |
| RPS2 | ribosomal protein S2 | 0.0480978 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0475216 |
| DOK5 | docking protein 5 | 0.045924 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0443187 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0429018 |
| OSMR | oncostatin M receptor | 0.0427515 |
| EMP1 | epithelial membrane protein 1 | 0.0411995 |
| LAMC2 | laminin, gamma 2 | 0.0408992 |
| MSN | moesin | 0.0395373 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391673 |
| CD44 | CD44 molecule (Indian blood group) | 0.0390052 |
| DPYD | dihydropyrimidine dehydrogenase | 0.038643 |
| DIAPH1 | diaphanous-related formin 1 | 0.0369571 |
| SMAD3 | SMAD family member 3 | 0.0353074 |
| LUZP1 | leucine zipper protein 1 | 0.0348912 |
| HLA-E | major histocompatibility complex, class I, E | 0.0339016 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0329425 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0325227 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.032129 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.031945 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0313431 |
| DUSP6 | dual specificity phosphatase 6 | 0.0309167 |
| RASAL2 | RAS protein activator like 2 | 0.0308833 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0308705 |
| MCL1 | myeloid cell leukemia 1 | 0.0299836 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0295645 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0293946 |
| CDCP1 | CUB domain containing protein 1 | 0.0284737 |
| SIK3 | SIK family kinase 3 | 0.0280466 |
| SMYD3 | SET and MYND domain containing 3 | 0.0268832 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0267562 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0267354 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.02594 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.025681 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.025372 |
| LDLR | low density lipoprotein receptor | 0.0253014 |
| EHF | ets homologous factor | 0.0252268 |
| UBC | ubiquitin C | 0.0251934 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0251881 |
| ENO1 | enolase 1, (alpha) | 0.0250869 |
| IFI44L | interferon-induced protein 44-like | 0.0250735 |
| RPL3 | ribosomal protein L3 | 0.025038 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.024777 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0237531 |
| TPM3 | tropomyosin 3 | 0.0234709 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0233182 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0233026 |
| OXSR1 | oxidative stress responsive 1 | 0.0231846 |
| TSPAN3 | tetraspanin 3 | 0.0229629 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0227523 |
| AHNAK | AHNAK nucleoprotein | 0.0224066 |
| CSTB | cystatin B (stefin B) | 0.0223853 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0221863 |
| MX1 | MX dynamin-like GTPase 1 | 0.021996 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0218124 |
| MYO9A | myosin IXA | 0.0215228 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0212051 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0210697 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0209588 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.020911 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.0208195 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0205681 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0203625 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0201678 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0201421 |
| SET | SET nuclear proto-oncogene | 0.0201321 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0199872 |
| TMC5 | transmembrane channel-like 5 | 0.0197749 |
| FAM107B | family with sequence similarity 107, member B | 0.0196547 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0195122 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0192188 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0186506 |
| APP | amyloid beta (A4) precursor protein | 0.0185406 |
| MECOM | MDS1 and EVI1 complex locus | 0.0184208 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0183416 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.017905 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0179034 |
| FN1 | fibronectin 1 | 0.0178159 |
| RPS8 | ribosomal protein S8 | 0.0178082 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0177081 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0175912 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0175849 |
| CEP250 | centrosomal protein 250kDa | 0.0175465 |
| RIN2 | Ras and Rab interactor 2 | 0.0173693 |
| TRIM56 | tripartite motif containing 56 | 0.0172784 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0172458 |
| FER | fer (fps/fes related) tyrosine kinase | 0.017098 |
| EZR | ezrin | 0.0170322 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.163755 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.160025 |
| PTMA | prothymosin, alpha | -0.119961 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.100148 |
| RPS21 | ribosomal protein S21 | -0.0960451 |
| NDRG1 | N-myc downstream regulated 1 | -0.0883115 |
| POTEF | POTE ankyrin domain family, member F | -0.0848607 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.082156 |
| S100A10 | S100 calcium binding protein A10 | -0.0799188 |
| RPLP2 | ribosomal protein, large, P2 | -0.0797993 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0791971 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0771553 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0751358 |
| CLU | clusterin | -0.0683701 |
| GNAS | GNAS complex locus | -0.063236 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0631319 |
| RPLP1 | ribosomal protein, large, P1 | -0.0629245 |
| ITGA6 | integrin, alpha 6 | -0.0604666 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0572927 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0564726 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0560523 |
| S100A2 | S100 calcium binding protein A2 | -0.0556951 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0552708 |
| RPS6 | ribosomal protein S6 | -0.0537087 |
| MORF4L2 | mortality factor 4 like 2 | -0.0533672 |
| S100A6 | S100 calcium binding protein A6 | -0.0527763 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0505358 |
| PLS3 | plastin 3 | -0.0503515 |
| KRT17 | keratin 17, type I | -0.0502874 |
| GRB10 | growth factor receptor-bound protein 10 | -0.050075 |
| LDHA | lactate dehydrogenase A | -0.0499862 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0484965 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0484764 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0477131 |
| RPL35A | ribosomal protein L35a | -0.0475018 |
| RBM39 | RNA binding motif protein 39 | -0.0471216 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0470863 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0461909 |
| MT1X | metallothionein 1X | -0.0454451 |
| CALR | calreticulin | -0.0451729 |
| TAGLN2 | transgelin 2 | -0.044712 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0442331 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0438779 |
| B2M | beta-2-microglobulin | -0.0432699 |
| TMSB4X | thymosin beta 4, X-linked | -0.042944 |
| MT2A | metallothionein 2A | -0.0428285 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0425476 |
| RPS13 | ribosomal protein S13 | -0.0423191 |
| VCL | vinculin | -0.0419537 |
| IGF2 | insulin-like growth factor 2 | -0.0412323 |
| GOLGA4 | golgin A4 | -0.0409861 |
| RPS4X | ribosomal protein S4, X-linked | -0.0409328 |
| PKM | pyruvate kinase, muscle | -0.0405971 |
| RPL11 | ribosomal protein L11 | -0.0405313 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0401875 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0400548 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0399381 |
| PFN1 | profilin 1 | -0.0390714 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.038283 |
| RIGI | RNA sensor RIG-I | -0.0380906 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0379025 |
| RPS23 | ribosomal protein S23 | -0.0374078 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.037243 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0371501 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0370399 |
| SPAG9 | sperm associated antigen 9 | -0.037018 |
| RPS11 | ribosomal protein S11 | -0.0369671 |
| LAMA5 | laminin, alpha 5 | -0.0354867 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0352582 |
| COG5 | component of oligomeric golgi complex 5 | -0.0345147 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0342241 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0341935 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0341568 |
| TOP1 | topoisomerase (DNA) I | -0.0340995 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0337947 |
| RPS24 | ribosomal protein S24 | -0.0335921 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0334651 |
| RNF145 | ring finger protein 145 | -0.0331272 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0330999 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0329582 |
| FLNB | filamin B, beta | -0.0328152 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0327737 |
| CANX | calnexin | -0.0326295 |
| RPL23 | ribosomal protein L23 | -0.0323011 |
| SERTAD2 | SERTA domain containing 2 | -0.0322631 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0321421 |
| GLYAT | glycine-N-acyltransferase | -0.0320746 |
| WASF2 | WAS protein family, member 2 | -0.0316889 |
| EFHD2 | EF-hand domain family, member D2 | -0.0316093 |
| SRPK2 | SRSF protein kinase 2 | -0.0315657 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0315544 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0312144 |
| SCFD1 | sec1 family domain containing 1 | -0.0312141 |
| PHF21A | PHD finger protein 21A | -0.03091 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0305583 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0304774 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0302393 |
| RPL19 | ribosomal protein L19 | -0.0301953 |
| S100A9 | S100 calcium binding protein A9 | -0.0301564 |
| RIOK3 | RIO kinase 3 | -0.0300241 |
