| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.16586 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.126952 |
| MYO1E | myosin IE | 0.0882059 |
| EZR | ezrin | 0.0876867 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.081621 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0674318 |
| LMO7 | LIM domain 7 | 0.0669247 |
| H1-0 | H1.0 linker histone | 0.0633933 |
| AHNAK | AHNAK nucleoprotein | 0.0594481 |
| DSPP | dentin sialophosphoprotein | 0.0576554 |
| ENO1 | enolase 1, (alpha) | 0.0534439 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0529301 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0523267 |
| EMP1 | epithelial membrane protein 1 | 0.0488131 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0479507 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0477094 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.046531 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0451491 |
| SVIL | supervillin | 0.0448867 |
| ANXA2 | annexin A2 | 0.0426764 |
| ASPH | aspartate beta-hydroxylase | 0.0416278 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0412059 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0406079 |
| RPL4 | ribosomal protein L4 | 0.0404314 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0403892 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0400229 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0400066 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0392632 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0386997 |
| SMYD3 | SET and MYND domain containing 3 | 0.0385116 |
| MUC17 | mucin 17, cell surface associated | 0.0379245 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0360112 |
| ANXA1 | annexin A1 | 0.0359997 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0357737 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0357415 |
| MUC13 | mucin 13, cell surface associated | 0.0356464 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0356038 |
| DSG2 | desmoglein 2 | 0.0354871 |
| NEBL | nebulette | 0.0342348 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0339602 |
| EGFR | epidermal growth factor receptor | 0.0332691 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0330936 |
| RNF217 | ring finger protein 217 | 0.0329114 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0323943 |
| PCDH9 | protocadherin 9 | 0.032091 |
| MT2A | metallothionein 2A | 0.0317436 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.03075 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0307481 |
| LAMC2 | laminin, gamma 2 | 0.0305572 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0299745 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0297758 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0286624 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0285592 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0282913 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0282904 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0282105 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0281379 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0277691 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0274999 |
| FRMD5 | FERM domain containing 5 | 0.0272086 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0270255 |
| RORA | RAR-related orphan receptor A | 0.0269081 |
| PIGR | polymeric immunoglobulin receptor | 0.0268375 |
| JUN | jun proto-oncogene | 0.0268167 |
| VCAN | versican | 0.0267808 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0265908 |
| AUTS2 | autism susceptibility candidate 2 | 0.0264044 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0263563 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0260556 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0259959 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0258009 |
| USP6NL | USP6 N-terminal like | 0.0255317 |
| APP | amyloid beta (A4) precursor protein | 0.025478 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0252511 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0252399 |
| EHBP1 | EH domain binding protein 1 | 0.0249747 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0245917 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0241966 |
| FOXP1 | forkhead box P1 | 0.0241774 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0237987 |
| FHIT | fragile histidine triad | 0.0237411 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0237308 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0236376 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0235198 |
| PCBP1 | poly(rC) binding protein 1 | 0.022708 |
| TJP1 | tight junction protein 1 | 0.0225043 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0222904 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0222123 |
| HMGA2 | high mobility group AT-hook 2 | 0.0220275 |
| RIGI | RNA sensor RIG-I | 0.021925 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0218014 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0217285 |
| CCDC146 | coiled-coil domain containing 146 | 0.0216234 |
| ATXN1 | ataxin 1 | 0.021603 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0214931 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0214141 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0213657 |
| TMC5 | transmembrane channel-like 5 | 0.0213646 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0213156 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.148327 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132691 |
| TMSB10 | thymosin beta 10 | -0.13031 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.120998 |
| GOLGA4 | golgin A4 | -0.0899229 |
| PTMA | prothymosin, alpha | -0.0773305 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0757724 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0710761 |
| RNF145 | ring finger protein 145 | -0.0696381 |
| HMGA1 | high mobility group AT-hook 1 | -0.065411 |
| RPL23 | ribosomal protein L23 | -0.0645421 |
| RNF43 | ring finger protein 43 | -0.0638229 |
| VEGFA | vascular endothelial growth factor A | -0.0625942 |
| TNS4 | tensin 4 | -0.0617559 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.058914 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0569403 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0558952 |
| NDRG1 | N-myc downstream regulated 1 | -0.0551613 |
| RBM39 | RNA binding motif protein 39 | -0.0550999 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0550371 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0543437 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0538836 |
| MED13L | mediator complex subunit 13-like | -0.0537699 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0514662 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0503615 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0499491 |
| SETD5 | SET domain containing 5 | -0.0497266 |
| COG5 | component of oligomeric golgi complex 5 | -0.0494652 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.047136 |
| GPHN | gephyrin | -0.0468445 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0467941 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0466471 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0457851 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0436809 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0436115 |
| RPL35A | ribosomal protein L35a | -0.0426018 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0423564 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0419548 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0417381 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0414196 |
| S100P | S100 calcium binding protein P | -0.0409904 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0409372 |
| TFG | TRK-fused gene | -0.040794 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0407361 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0404518 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0402647 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0399735 |
| RPS19 | ribosomal protein S19 | -0.0395434 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0392893 |
| INSIG1 | insulin induced gene 1 | -0.0392348 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0387996 |
| RPS6 | ribosomal protein S6 | -0.0387082 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0384978 |
| POTEF | POTE ankyrin domain family, member F | -0.0375594 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0372134 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0370797 |
| WDR43 | WD repeat domain 43 | -0.0368969 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0367049 |
| RPS24 | ribosomal protein S24 | -0.0364702 |
| TOP1 | topoisomerase (DNA) I | -0.0362473 |
| OGA | O-GlcNAcase | -0.0355642 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0355376 |
| KRT8 | keratin 8, type II | -0.0353989 |
| VCL | vinculin | -0.0353892 |
| PKM | pyruvate kinase, muscle | -0.035218 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0348904 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0348168 |
| CALR | calreticulin | -0.0348155 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0347946 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0344348 |
| RBM25 | RNA binding motif protein 25 | -0.0341512 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0340168 |
| RPLP1 | ribosomal protein, large, P1 | -0.0340122 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0339765 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0337623 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0337475 |
| RPLP2 | ribosomal protein, large, P2 | -0.0331657 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0326495 |
| RPL5 | ribosomal protein L5 | -0.0326226 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.032178 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0320639 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0319508 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0317895 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0313491 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309716 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0308666 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0305251 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0304153 |
| CCNL1 | cyclin L1 | -0.0304055 |
| PCDHB16 | protocadherin beta 16 | -0.0299207 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0298758 |
| RPS3 | ribosomal protein S3 | -0.0295785 |
| NUP58 | nucleoporin 58 | -0.029484 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0289973 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0289304 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0289071 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0288215 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0284946 |
| COPA | coatomer protein complex, subunit alpha | -0.028431 |
| NBAS | neuroblastoma amplified sequence | -0.028248 |
