| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.148749 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.11138 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0997899 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0970466 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0937357 |
| HLA-B | major histocompatibility complex, class I, B | 0.0906863 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0797494 |
| CAPRIN2 | caprin family member 2 | 0.0779724 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0659862 |
| FMNL2 | formin-like 2 | 0.0650399 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0581548 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0576153 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0563943 |
| KLF6 | Kruppel-like factor 6 | 0.0558406 |
| JUN | jun proto-oncogene | 0.0543494 |
| EZR | ezrin | 0.0533102 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0531501 |
| ANGPTL4 | angiopoietin-like 4 | 0.0516205 |
| HLA-A | major histocompatibility complex, class I, A | 0.0493506 |
| JMJD1C | jumonji domain containing 1C | 0.0476628 |
| CD44 | CD44 molecule (Indian blood group) | 0.0460608 |
| EREG | epiregulin | 0.0449761 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0445602 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0444586 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0417398 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0412421 |
| DST | dystonin | 0.039613 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0388707 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0380621 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0376634 |
| B2M | beta-2-microglobulin | 0.037648 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0374154 |
| SEC24A | SEC24 family member A | 0.036947 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.036237 |
| H1-0 | H1.0 linker histone | 0.0359428 |
| SYAP1 | synapse associated protein 1 | 0.0356603 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0349403 |
| RUNX1 | runt-related transcription factor 1 | 0.0329984 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0328558 |
| RPS12 | ribosomal protein S12 | 0.0328364 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.032667 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.032565 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0323043 |
| STXBP1 | syntaxin binding protein 1 | 0.0321469 |
| RPL36 | ribosomal protein L36 | 0.0320641 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0319805 |
| VEGFC | vascular endothelial growth factor C | 0.0317959 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0304748 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0304627 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0297178 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0290624 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0288909 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0287092 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0286445 |
| RPL12 | ribosomal protein L12 | 0.0285801 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0275543 |
| SQSTM1 | sequestosome 1 | 0.027366 |
| TRIM56 | tripartite motif containing 56 | 0.0273462 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0269039 |
| PARD3 | par-3 family cell polarity regulator | 0.0266226 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0263772 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0260991 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0259331 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0256681 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0255949 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0252946 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0251165 |
| PDE8A | phosphodiesterase 8A | 0.0251047 |
| MT2A | metallothionein 2A | 0.0249845 |
| VMP1 | vacuole membrane protein 1 | 0.0243525 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.024126 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.024069 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0240288 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0240231 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240022 |
| PRKCE | protein kinase C, epsilon | 0.0239157 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0238106 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0234041 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.023344 |
| PGK1 | phosphoglycerate kinase 1 | 0.0230769 |
| IRS1 | insulin receptor substrate 1 | 0.0228652 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.022863 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0226921 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0224403 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0223793 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0222436 |
| AHI1 | Abelson helper integration site 1 | 0.0220123 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0219504 |
| PFKP | phosphofructokinase, platelet | 0.0218935 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0217584 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.02173 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0216766 |
| PHF10 | PHD finger protein 10 | 0.0216582 |
| WDR26 | WD repeat domain 26 | 0.0215411 |
| PHF21A | PHD finger protein 21A | 0.0213731 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0213034 |
| PRELID2 | PRELI domain containing 2 | 0.0211846 |
| ANXA2 | annexin A2 | 0.0207619 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0207126 |
| ARFGEF3 | ARFGEF family member 3 | 0.0206116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.295425 |
| POTEF | POTE ankyrin domain family, member F | -0.165922 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.114668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0966824 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0954109 |
| EGR1 | early growth response 1 | -0.0943821 |
| TMSB10 | thymosin beta 10 | -0.0866564 |
| HMGA1 | high mobility group AT-hook 1 | -0.0861471 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0817266 |
| LDHA | lactate dehydrogenase A | -0.0789751 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.074524 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0721183 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0695468 |
| PKM | pyruvate kinase, muscle | -0.0664254 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0659166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0616757 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0590054 |
| PTMA | prothymosin, alpha | -0.0585629 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0582084 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0564789 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.054883 |
| TAPBP | TAP binding protein (tapasin) | -0.0511059 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0492693 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0480552 |
| TNS3 | tensin 3 | -0.0474287 |
| YBX1 | Y box binding protein 1 | -0.0470716 |
| FTL | ferritin, light polypeptide | -0.0462007 |
| RPL5 | ribosomal protein L5 | -0.0439542 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0421695 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0411018 |
| CALR | calreticulin | -0.0395053 |
| USP34 | ubiquitin specific peptidase 34 | -0.0374924 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0369728 |
| CENPF | centromere protein F, 350/400kDa | -0.0368167 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0364108 |
| RPL23 | ribosomal protein L23 | -0.0363245 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0356126 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0352726 |
| EHBP1 | EH domain binding protein 1 | -0.0347053 |
| CMIP | c-Maf inducing protein | -0.0343787 |
| RPL35A | ribosomal protein L35a | -0.0337673 |
| EGFR | epidermal growth factor receptor | -0.0333295 |
| CANX | calnexin | -0.0331917 |
| ZNF207 | zinc finger protein 207 | -0.0325058 |
| CADM2 | cell adhesion molecule 2 | -0.0324825 |
| INTS6 | integrator complex subunit 6 | -0.0312101 |
| AEBP2 | AE binding protein 2 | -0.0308288 |
| MAP4 | microtubule-associated protein 4 | -0.0304361 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0302038 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0299017 |
| TXNRD1 | thioredoxin reductase 1 | -0.0290357 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0287298 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.02802 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0279556 |
| TUBB | tubulin, beta class I | -0.0279059 |
| FLNB | filamin B, beta | -0.0275991 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0275603 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0274686 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0273557 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0270208 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.026937 |
| TMSB4X | thymosin beta 4, X-linked | -0.0268572 |
| FBXO11 | F-box protein 11 | -0.0268435 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0266212 |
| RRM2 | ribonucleotide reductase M2 | -0.0265662 |
| UBC | ubiquitin C | -0.0262855 |
| MYO10 | myosin X | -0.0262258 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0252978 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.024815 |
| S100A10 | S100 calcium binding protein A10 | -0.0245965 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0245957 |
| MKI67 | marker of proliferation Ki-67 | -0.0245378 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0244643 |
| BSG | basigin (Ok blood group) | -0.0244191 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0244026 |
| BRD2 | bromodomain containing 2 | -0.0241269 |
| RPS4X | ribosomal protein S4, X-linked | -0.0239883 |
| OLA1 | Obg-like ATPase 1 | -0.023868 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0238354 |
| NEK10 | NIMA-related kinase 10 | -0.023799 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0237666 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0237395 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0231727 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0230255 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) | -0.0227147 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0224376 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0223506 |
| TPI1 | triosephosphate isomerase 1 | -0.0221311 |
| RPS24 | ribosomal protein S24 | -0.021997 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0215733 |
| FOXN3 | forkhead box N3 | -0.0215305 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0215224 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0213005 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0210913 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.021058 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0209013 |
| RPS20 | ribosomal protein S20 | -0.020888 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0208817 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0206875 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0206572 |
