| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.120949 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.109283 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.106011 |
| STC1 | stanniocalcin 1 | 0.102903 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0870178 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0735819 |
| EFNA5 | ephrin-A5 | 0.0679424 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0630768 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0604793 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0565531 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0528461 |
| LAMA4 | laminin, alpha 4 | 0.0522091 |
| AREG | amphiregulin | 0.0498333 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0489772 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0481105 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0477118 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0457933 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0452425 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0428766 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0428654 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0427098 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0410727 |
| ARRDC3 | arrestin domain containing 3 | 0.0402445 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0401837 |
| ENO1 | enolase 1, (alpha) | 0.0391957 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0383219 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.037487 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0362629 |
| YBX3 | Y box binding protein 3 | 0.0352687 |
| LAMC2 | laminin, gamma 2 | 0.0344742 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0331507 |
| CES1 | carboxylesterase 1 | 0.0328437 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0325906 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0325272 |
| SMAD3 | SMAD family member 3 | 0.0322755 |
| B2M | beta-2-microglobulin | 0.0305056 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303532 |
| EMP1 | epithelial membrane protein 1 | 0.0301839 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0293272 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0289434 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0285404 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0278689 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0274575 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.027085 |
| FOXP1 | forkhead box P1 | 0.0266739 |
| SLTM | SAFB-like, transcription modulator | 0.0265587 |
| TRIM56 | tripartite motif containing 56 | 0.026376 |
| EPAS1 | endothelial PAS domain protein 1 | 0.025886 |
| MACC1 | metastasis associated in colon cancer 1 | 0.024748 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0245126 |
| PDE8A | phosphodiesterase 8A | 0.0242623 |
| LAMB3 | laminin, beta 3 | 0.0236199 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0232297 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0227038 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0226676 |
| CDCP1 | CUB domain containing protein 1 | 0.0224911 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0223456 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0221262 |
| IFI44L | interferon-induced protein 44-like | 0.0221183 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0209622 |
| ACTG1 | actin gamma 1 | 0.0207686 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0206306 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0205186 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0203565 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0203159 |
| SMYD3 | SET and MYND domain containing 3 | 0.0202104 |
| RNF149 | ring finger protein 149 | 0.0197052 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0196027 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0194259 |
| SLMAP | sarcolemma associated protein | 0.0193155 |
| USP3 | ubiquitin specific peptidase 3 | 0.01897 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0189118 |
| DSG2 | desmoglein 2 | 0.0188258 |
| FOSL1 | FOS-like antigen 1 | 0.0188042 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0187318 |
| KIFC3 | kinesin family member C3 | 0.0185781 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.018263 |
| TPM3 | tropomyosin 3 | 0.0182371 |
| PGK1 | phosphoglycerate kinase 1 | 0.0181808 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0178509 |
| TMEM45B | transmembrane protein 45B | 0.0176269 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0175747 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0174958 |
| NCKAP1 | NCK-associated protein 1 | 0.0174853 |
| MLKL | mixed lineage kinase domain-like | 0.0174717 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0173954 |
| CRY1 | cryptochrome circadian clock 1 | 0.0172875 |
| FAM107B | family with sequence similarity 107, member B | 0.0169704 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0168984 |
| RPS2 | ribosomal protein S2 | 0.0168832 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0168318 |
| ABHD17C | abhydrolase domain containing 17C | 0.0168301 |
| H1-0 | H1.0 linker histone | 0.0164856 |
| S100A10 | S100 calcium binding protein A10 | 0.0163856 |
| MLF1 | myeloid leukemia factor 1 | 0.0163456 |
| MX1 | MX dynamin-like GTPase 1 | 0.0162715 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0161483 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0160082 |
| MSN | moesin | 0.0159056 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.0158476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.319153 |
| INTS6 | integrator complex subunit 6 | -0.106671 |
| RPL35A | ribosomal protein L35a | -0.0764047 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0679981 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0634974 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0626951 |
| TXNRD1 | thioredoxin reductase 1 | -0.062001 |
| TMSB10 | thymosin beta 10 | -0.0613365 |
| NABP1 | nucleic acid binding protein 1 | -0.0603259 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0593817 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0487413 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0479766 |
| USP34 | ubiquitin specific peptidase 34 | -0.0479164 |
| HDLBP | high density lipoprotein binding protein | -0.0460265 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0442326 |
| GSK3B | glycogen synthase kinase 3 beta | -0.043527 |
| PATJ | PATJ crumbs cell polarity complex component | -0.042173 |
| RPLP1 | ribosomal protein, large, P1 | -0.0415855 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0395455 |
| RPS23 | ribosomal protein S23 | -0.0384766 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0376733 |
| WASF2 | WAS protein family, member 2 | -0.0376511 |
| HOMER1 | homer scaffolding protein 1 | -0.0372134 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0363608 |
| MYOF | myoferlin | -0.0360402 |
| GOLGB1 | golgin B1 | -0.0354201 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0352368 |
| FTL | ferritin, light polypeptide | -0.0348372 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0341658 |
| RPS25 | ribosomal protein S25 | -0.0324489 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0322423 |
| RPL31 | ribosomal protein L31 | -0.0319201 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0317021 |
| VCL | vinculin | -0.0315799 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0313919 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0312133 |
| TOP1 | topoisomerase (DNA) I | -0.0308717 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0308312 |
| CANX | calnexin | -0.0297034 |
| ASPH | aspartate beta-hydroxylase | -0.0293449 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0289257 |
| SEPTIN2 | septin 2 | -0.0280301 |
| ZNF638 | zinc finger protein 638 | -0.0277966 |
| KRT8 | keratin 8, type II | -0.0277144 |
| RPS8 | ribosomal protein S8 | -0.0274923 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0271128 |
| AEBP2 | AE binding protein 2 | -0.0270738 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0268589 |
| FBXO11 | F-box protein 11 | -0.0267177 |
| RPS24 | ribosomal protein S24 | -0.0265488 |
| PKM | pyruvate kinase, muscle | -0.0264916 |
| TUFT1 | tuftelin 1 | -0.0264351 |
| RPL5 | ribosomal protein L5 | -0.0263609 |
| PTMA | prothymosin, alpha | -0.0262566 |
| RPL7 | ribosomal protein L7 | -0.0261718 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0258355 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.0255887 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0255359 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0254256 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0253103 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0252925 |
| FNIP1 | folliculin interacting protein 1 | -0.0248757 |
| ZNF207 | zinc finger protein 207 | -0.0248428 |
| RPL37A | ribosomal protein L37a | -0.0247356 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.0243406 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0240259 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0240101 |
| RPS6 | ribosomal protein S6 | -0.0238572 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0236601 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.02365 |
| GPATCH2L | G patch domain containing 2-like | -0.0235609 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0234844 |
| MKI67 | marker of proliferation Ki-67 | -0.0234817 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0234264 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0232091 |
| MORF4L2 | mortality factor 4 like 2 | -0.0231345 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0230623 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0229718 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0226502 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0225524 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.022148 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0221474 |
| FAM193A | family with sequence similarity 193, member A | -0.0221348 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0221091 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0220098 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.021629 |
| SCEL | sciellin | -0.0214824 |
| TES | testin LIM domain protein | -0.0214641 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0212947 |
| SPAG9 | sperm associated antigen 9 | -0.0212608 |
| RPS16 | ribosomal protein S16 | -0.0211968 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.021164 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0211052 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0210836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0210667 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0210218 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0208951 |
| WDR49 | WD repeat domain 49 | -0.0208883 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0207201 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0205559 |
