| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Bergenin perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Bergenin_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.0921177 |
| PDE10A | phosphodiesterase 10A | 0.0824644 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0788962 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0760597 |
| ATOSA | atos homolog A | 0.0711634 |
| HMGA2 | high mobility group AT-hook 2 | 0.0678966 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0676287 |
| PRKCA | protein kinase C, alpha | 0.0670972 |
| RORA | RAR-related orphan receptor A | 0.0652452 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.062725 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0616492 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0567897 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0560352 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0554345 |
| PCBP3 | poly(rC) binding protein 3 | 0.0550221 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0533877 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0528398 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0517331 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0511237 |
| SETX | senataxin | 0.0510774 |
| VCL | vinculin | 0.0507894 |
| MYOF | myoferlin | 0.0489159 |
| GPC6 | glypican 6 | 0.0484758 |
| KYNU | kynureninase | 0.0477083 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0470358 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0468152 |
| GLIS3 | GLIS family zinc finger 3 | 0.0457061 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0452731 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0434049 |
| MAP1B | microtubule-associated protein 1B | 0.0431147 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0429793 |
| INHBA | inhibin, beta A | 0.0421902 |
| RNF149 | ring finger protein 149 | 0.0421423 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0419703 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0416814 |
| LAMA4 | laminin, alpha 4 | 0.0416752 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0413836 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0412842 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0407711 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0405644 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0393246 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0387138 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0387105 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0384837 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0381396 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0375182 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0374143 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0372289 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0366736 |
| STK4 | serine/threonine kinase 4 | 0.0366278 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0363515 |
| MYO10 | myosin X | 0.0362153 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0360324 |
| NBEAL1 | neurobeachin-like 1 | 0.0358297 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0358128 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0357349 |
| USP34 | ubiquitin specific peptidase 34 | 0.0350165 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.034995 |
| VGF | VGF nerve growth factor inducible | 0.0349441 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0349256 |
| NABP1 | nucleic acid binding protein 1 | 0.03473 |
| MEIS1 | Meis homeobox 1 | 0.0345745 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0345257 |
| RASA2 | RAS p21 protein activator 2 | 0.0343959 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0341934 |
| EHBP1 | EH domain binding protein 1 | 0.0338418 |
| PLAUR | plasminogen activator, urokinase receptor | 0.03382 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0328803 |
| EXOC4 | exocyst complex component 4 | 0.0327956 |
| UBXN4 | UBX domain protein 4 | 0.0326903 |
| PMM2 | phosphomannomutase 2 | 0.0324423 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0324338 |
| RAD51B | RAD51 paralog B | 0.0320866 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0318603 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0317191 |
| CUL3 | cullin 3 | 0.0315207 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0314198 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0312129 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0312116 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0308964 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0304743 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.0303092 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0301467 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0301239 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0300597 |
| INSIG1 | insulin induced gene 1 | 0.030023 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0299747 |
| CD44 | CD44 molecule (Indian blood group) | 0.0299037 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0297981 |
| FMNL2 | formin-like 2 | 0.0297696 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0296845 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0293435 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0293237 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0291379 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0290919 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0290817 |
| SSR1 | signal sequence receptor, alpha | 0.0289725 |
| CPE | carboxypeptidase E | 0.0289146 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0288897 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0288297 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207099 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.169939 |
| PTMA | prothymosin, alpha | -0.168498 |
| TMSB10 | thymosin beta 10 | -0.15641 |
| LMO7 | LIM domain 7 | -0.119907 |
| VIM | vimentin | -0.0957421 |
| POTEF | POTE ankyrin domain family, member F | -0.0873825 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.086964 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0817771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.080995 |
| FTL | ferritin, light polypeptide | -0.0770646 |
| PKM | pyruvate kinase, muscle | -0.0720344 |
| RPL35A | ribosomal protein L35a | -0.071892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0696897 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0678666 |
| PGK1 | phosphoglycerate kinase 1 | -0.0654695 |
| RPS6 | ribosomal protein S6 | -0.0643042 |
| ACTG1 | actin gamma 1 | -0.0615046 |
| LAMB3 | laminin, beta 3 | -0.0587533 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0579364 |
| S100A10 | S100 calcium binding protein A10 | -0.0572868 |
| KRT17 | keratin 17, type I | -0.0571975 |
| RPL19 | ribosomal protein L19 | -0.0569265 |
| CALR | calreticulin | -0.0565334 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0549695 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.054153 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0538878 |
| RPLP1 | ribosomal protein, large, P1 | -0.0538075 |
| RPS19 | ribosomal protein S19 | -0.0521063 |
| B2M | beta-2-microglobulin | -0.0511447 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.050648 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0493699 |
| S100A6 | S100 calcium binding protein A6 | -0.0490529 |
| RBM25 | RNA binding motif protein 25 | -0.0482009 |
| AHNAK | AHNAK nucleoprotein | -0.0480849 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0477229 |
| LDHA | lactate dehydrogenase A | -0.0474994 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0474944 |
| RPL31 | ribosomal protein L31 | -0.0467254 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0458602 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0448023 |
| HLA-B | major histocompatibility complex, class I, B | -0.0447611 |
| TFG | TRK-fused gene | -0.0431643 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0430948 |
| RPS8 | ribosomal protein S8 | -0.0427591 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0421996 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0407329 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0400198 |
| RPL23 | ribosomal protein L23 | -0.040003 |
| RPL37 | ribosomal protein L37 | -0.039736 |
| UBC | ubiquitin C | -0.0395061 |
| WASF2 | WAS protein family, member 2 | -0.0390671 |
| RPL7A | ribosomal protein L7a | -0.0390426 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0387793 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0386003 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0384591 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0383893 |
| NDRG1 | N-myc downstream regulated 1 | -0.038075 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0380268 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0379989 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0373392 |
| RPS15 | ribosomal protein S15 | -0.0368009 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0367615 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0360746 |
| FUS | FUS RNA binding protein | -0.0358845 |
| CANX | calnexin | -0.0358681 |
| RPL9 | ribosomal protein L9 | -0.0358237 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0357523 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0354837 |
| RPL11 | ribosomal protein L11 | -0.0354092 |
| SETD5 | SET domain containing 5 | -0.035363 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0351839 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0347013 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0344314 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.034352 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0338474 |
| RPL12 | ribosomal protein L12 | -0.0337178 |
| FMN1 | formin 1 | -0.0336054 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.03321 |
| RPS27 | ribosomal protein S27 | -0.0331803 |
| ETNK1 | ethanolamine kinase 1 | -0.0331237 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0323325 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | -0.0321294 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0321254 |
| RPS3 | ribosomal protein S3 | -0.0320977 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.032021 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0315544 |
| RPS10 | ribosomal protein S10 | -0.0314931 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0313084 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0310089 |
| RPL21 | ribosomal protein L21 | -0.0305076 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0302245 |
| PCBP2 | poly(rC) binding protein 2 | -0.0302232 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0300978 |
| RPS25 | ribosomal protein S25 | -0.0298259 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0296309 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0291559 |
| RRBP1 | ribosome binding protein 1 | -0.0289629 |
| RPS11 | ribosomal protein S11 | -0.0289317 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0289273 |
